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Protein

Triosephosphate isomerase

Gene

PFNF135_05901

Organism
Plasmodium falciparum NF135/5.C10
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glyceraldehyde 3-phosphate = glycerone phosphate.UniRule annotation

Pathwayi: gluconeogenesis

This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

Pathwayi: glycolysis

This protein is involved in step 1 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate from glycerone phosphate.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Triosephosphate isomerase (PFNF135_00605), Triosephosphate isomerase (PFNF135_05901)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate from glycerone phosphate, the pathway glycolysis and in Carbohydrate degradation.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationImported
Biological processGluconeogenesisUniRule annotation, GlycolysisUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00109; UER00189
UPA00138

Names & Taxonomyi

Protein namesi
Recommended name:
Triosephosphate isomeraseUniRule annotation (EC:5.3.1.1UniRule annotation)
Gene namesi
ORF Names:PFNF135_05901Imported
OrganismiPlasmodium falciparum NF135/5.C10Imported
Taxonomic identifieri1036726 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000019114 Componenti: Unassembled WGS sequence

Structurei

3D structure databases

ProteinModelPortaliW4IA04
SMRiW4IA04
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the triosephosphate isomerase family.UniRule annotation

Family and domain databases

CDDicd00311 TIM, 1 hit
Gene3Di3.20.20.70, 1 hit
HAMAPiMF_00147_B TIM_B, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR035990 TIM_sf
IPR022896 TrioseP_Isoase_bac/euk
IPR000652 Triosephosphate_isomerase
IPR020861 Triosephosphate_isomerase_AS
PANTHERiPTHR21139 PTHR21139, 1 hit
PfamiView protein in Pfam
PF00121 TIM, 1 hit
SUPFAMiSSF51351 SSF51351, 1 hit
TIGRFAMsiTIGR00419 tim, 1 hit
PROSITEiView protein in PROSITE
PS00171 TIM_1, 1 hit
PS51440 TIM_2, 1 hit

Sequencei

Sequence statusi: Complete.

W4IA04-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARKYFVAAN WKCNGTLESI KSLTNSFNNL DFDPSKLDVV VFPVSVHYDH
60 70 80 90 100
TRKLLQSKFS TGIQNVSKFG NGSYTGEVSA EIAKDLNIEY VIIGHFERRK
110 120 130 140 150
YFHETDEDVR EKLQASLKNN LKAVVCFGES LEQREQNKTI EVITKQVKAF
160 170 180 190 200
VDLIDNFDNV ILAYEPLWAI GTGKTATPEQ AQLVHKEIRK IVKDTCGEKQ
210 220 230 240
ANQIRILYGG SVNTENCSSL IQQEDIDGFL VGNASLKESF VDIIKSAM
Length:248
Mass (Da):27,935
Last modified:March 19, 2014 - v1
Checksum:iEFC8A4373EA9BED1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KI926126 Genomic DNA Translation: ETW39874.1

Genome annotation databases

EnsemblProtistsiETW39874; ETW39874; PFNF135_05901

Similar proteinsi

Entry informationi

Entry nameiW4IA04_PLAFA
AccessioniPrimary (citable) accession number: W4IA04
Entry historyiIntegrated into UniProtKB/TrEMBL: March 19, 2014
Last sequence update: March 19, 2014
Last modified: June 20, 2018
This is version 21 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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