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Protein

V-type proton ATPase subunit a

Gene

PFICI_09323

Organism
Pestalotiopsis fici (strain W106-1 / CGMCC3.15140)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processHydrogen ion transportUniRule annotation, Ion transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
V-type proton ATPase subunit aUniRule annotation
Gene namesi
ORF Names:PFICI_09323Imported
OrganismiPestalotiopsis fici (strain W106-1 / CGMCC3.15140)Imported
Taxonomic identifieri1229662 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesXylariomycetidaeXylarialesSporocadaceaePestalotiopsis
Proteomesi
  • UP000030651 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei456 – 480HelicalUniRule annotationAdd BLAST25
Transmembranei492 – 517HelicalUniRule annotationAdd BLAST26
Transmembranei581 – 599HelicalUniRule annotationAdd BLAST19
Transmembranei611 – 636HelicalUniRule annotationAdd BLAST26
Transmembranei673 – 693HelicalUniRule annotationAdd BLAST21
Transmembranei792 – 815HelicalUniRule annotationAdd BLAST24
Transmembranei821 – 844HelicalUniRule annotationAdd BLAST24

Keywords - Cellular componenti

Membrane

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili135 – 162Sequence analysisAdd BLAST28
Coiled coili313 – 340Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the V-ATPase 116 kDa subunit family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

KOiK02154
OMAiLHWVEAN

Family and domain databases

InterProiView protein in InterPro
IPR002490 V-ATPase_116kDa_su
IPR026028 V-type_ATPase_116kDa_su_euka
PANTHERiPTHR11629 PTHR11629, 1 hit
PfamiView protein in Pfam
PF01496 V_ATPase_I, 1 hit
PIRSFiPIRSF001293 ATP6V0A1, 1 hit

Sequencei

Sequence statusi: Complete.

W3X040-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTLRCYGQAC NNLNITYDNL HLVKTRSFGA ISPIMAPNQT SMFRSADMSM
60 70 80 90 100
VQLYISNEIG REVVNALGEL GLVQFRDLNG DVSAFQRTFT QEIRRLDNVE
110 120 130 140 150
RQLRYFHSQM EKSNIPLRKL DLDVESLASP TTHEIDELAE RSQSLETRVA
160 170 180 190 200
SLNESYETLK KREVELTEWR WVLKEAGGFF DRAHGNVEEI RHSTEDDDAP
210 220 230 240 250
LLQDVEQNGQ AADADRSFSG MNIGFVAGVI PRDRVGPFER ILWRTLRGNL
260 270 280 290 300
YMNQSEIPEP LVDPTTNETV NKNVFVIFAH GKEILAKIRK ISESMGAELY
310 320 330 340 350
KVDEDGNERR DQVHEVNVRL NDLQNVLRNT QNTLEAELTQ IAQSLSAWMI
360 370 380 390 400
LVTKEKAAYQ TLNLFSFDKQ RRTLIAEGWC PTNDLPLIRS TLQDVTNRAG
410 420 430 440 450
LSVPSIINEI RTNKTPPTYL KTNKFTEAFQ TIINAYGTAT YQEVNPALPA
460 470 480 490 500
IVTFPFLFAV MFGDFGHAVI MFLASLAMIY WEKPLKKVTF ELFAMVYYGR
510 520 530 540 550
YIALVMSIFS LYTGLIYNDV FSKSLTLFDS AWKWNVPDDW KEGQTLDAQL
560 570 580 590 600
VSDYRYPFGI DWRWHGAEND LLFSNSYKMK MSIILGWFHM TYSLCLSYFN
610 620 630 640 650
ARHFKKPIDI WGNFVPGMIF FQSIFGYLVI CIIYKWSIDW SKADSSPPGL
660 670 680 690 700
LNMLIYMFLR PGFVDEQLYP GQGTVQVILL LLAFVQVPIL LFLKPFYLRW
710 720 730 740 750
EHNQARAKGY RGIGEHSRVS ALDEDEDGDG HVGNGRASFD TDDGQGGATG
760 770 780 790 800
QGDDDEEGHH EFEFSEIMIH QVIHTIEFCL NCISHTASYL RLWALSLAHQ
810 820 830 840 850
QLSVVLWSMT IGGVLSKTGA LGVIMIVIAF YLWFFLTCAI LIAMEGCSAM
860 870 880 890
LHSLRLQWVE AQSKYAEFAG HMFTPFSYGT LLEEDEGLAE FRG
Length:893
Mass (Da):101,871
Last modified:March 19, 2014 - v1
Checksum:i3C48BD369C6F5FF5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KI912114 Genomic DNA Translation: ETS79470.1
RefSeqiXP_007836095.1, XM_007837904.1

Genome annotation databases

EnsemblFungiiETS79470; ETS79470; PFICI_09323
GeneIDi19274336
KEGGipfy:PFICI_09323

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KI912114 Genomic DNA Translation: ETS79470.1
RefSeqiXP_007836095.1, XM_007837904.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiETS79470; ETS79470; PFICI_09323
GeneIDi19274336
KEGGipfy:PFICI_09323

Phylogenomic databases

KOiK02154
OMAiLHWVEAN

Family and domain databases

InterProiView protein in InterPro
IPR002490 V-ATPase_116kDa_su
IPR026028 V-type_ATPase_116kDa_su_euka
PANTHERiPTHR11629 PTHR11629, 1 hit
PfamiView protein in Pfam
PF01496 V_ATPase_I, 1 hit
PIRSFiPIRSF001293 ATP6V0A1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiW3X040_PESFW
AccessioniPrimary (citable) accession number: W3X040
Entry historyiIntegrated into UniProtKB/TrEMBL: March 19, 2014
Last sequence update: March 19, 2014
Last modified: November 7, 2018
This is version 19 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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