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Protein

6-carboxyhexanoate--CoA ligase

Gene

bioW

Organism
Veillonella dispar DORA_11
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

ATP + 6-carboxyhexanoate + CoA = AMP + diphosphate + 6-carboxyhexanoyl-CoA.UniRule annotation

Cofactori

Mg2+UniRule annotation

Pathwayi: pimeloyl-CoA biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes pimeloyl-CoA from pimelate.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. 6-carboxyhexanoate--CoA ligase (bioW)
This subpathway is part of the pathway pimeloyl-CoA biosynthesis, which is itself part of Metabolic intermediate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pimeloyl-CoA from pimelate, the pathway pimeloyl-CoA biosynthesis and in Metabolic intermediate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotationImported
Biological processBiotin biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, MagnesiumUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00999; UER00351

Names & Taxonomyi

Protein namesi
Recommended name:
6-carboxyhexanoate--CoA ligaseUniRule annotation (EC:6.2.1.14UniRule annotation)
Alternative name(s):
Pimeloyl-CoA synthaseUniRule annotation
Gene namesi
Name:bioWUniRule annotation
ORF Names:Q619_VDC00599G0026Imported
OrganismiVeillonella dispar DORA_11Imported
Taxonomic identifieri1403949 [NCBI]
Taxonomic lineageiBacteriaFirmicutesNegativicutesVeillonellalesVeillonellaceaeVeillonella
Proteomesi
  • UP000018855 Componenti: Unassembled WGS sequence

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the BioW family.UniRule annotation

Family and domain databases

HAMAPiMF_00668 BioW, 1 hit
InterProiView protein in InterPro
IPR005499 BioW
PfamiView protein in Pfam
PF03744 BioW, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD017229 BioW, 1 hit
TIGRFAMsiTIGR01204 bioW, 1 hit

Sequencei

Sequence statusi: Complete.

W1UX54-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDELYSVRMR AAQGGPHENG GHHISGAERI VTLNQVGSIA QSLAERALHH
60 70 80 90 100
SKGTADFINI TVDLIPAETI TYIECLKVNE HLANTVAEAH QLAVELLQGA
110 120 130 140 150
DISETAVKHA IFLLEGLDSS MRGAMLVDAI SGERIDSGNR GVRVSHMDSF
160 170 180 190 200
DSEKLGENEH MREALVLASK VQSAEGIVGE LCWSDDPDYT VGYVACNDIY
210 220 230 240
HRIPSMKEFG SNLGGRVFFV KPNTDVDCVI KYLEKAPVLV QR
Length:242
Mass (Da):26,413
Last modified:March 19, 2014 - v1
Checksum:i961032E3B0E42BED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AZMJ01000599 Genomic DNA Translation: ETI97259.1

Genome annotation databases

PATRICifig|1403949.3.peg.1731

Similar proteinsi

Entry informationi

Entry nameiW1UX54_9FIRM
AccessioniPrimary (citable) accession number: W1UX54
Entry historyiIntegrated into UniProtKB/TrEMBL: March 19, 2014
Last sequence update: March 19, 2014
Last modified: June 20, 2018
This is version 17 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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