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Protein
Submitted name:

Low affinity immunoglobulin gamma Fc region receptor II-a

Gene

FCGR2A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Low affinity immunoglobulin gamma Fc region receptor II-aImported
Gene namesi
Name:FCGR2AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000143226.13
HGNCiHGNC:3616 FCGR2A

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000143226

PTM / Processingi

Proteomic databases

PeptideAtlasiV9GY83
PRIDEiV9GY83

Expressioni

Gene expression databases

BgeeiENSG00000143226 Expressed in 106 organ(s), highest expression level in blood
ExpressionAtlasiV9GY83 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliV9GY83
SMRiV9GY83
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 83Ig-likeInterPro annotationAdd BLAST80
Domaini87 – 169Ig-likeInterPro annotationAdd BLAST83

Phylogenomic databases

eggNOGiENOG410J9AP Eukaryota
ENOG410YXNK LUCA
GeneTreeiENSGT00760000119130

Family and domain databases

Gene3Di2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR003598 Ig_sub2
PfamiView protein in Pfam
PF13895 Ig_2, 2 hits
SMARTiView protein in SMART
SM00409 IG, 2 hits
SM00408 IGc2, 2 hits
SUPFAMiSSF48726 SSF48726, 2 hits
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 2 hits

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

V9GY83-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
AAPPKAVLKL EPPWINVLQE DSVTLTCQGA RSPESDSIQW FHNGNLIPTH
60 70 80 90 100
TQPSYRFKAN NNDSGEYTCQ TGQTSLSDPV HLTVLSEWLV LQTPHLEFQE
110 120 130 140 150
GETIMLRCHS WKDKPLVKVT FFQNGKSQKF SHLDPTFSIP QANHSHSGDY
160 170 180 190
HCTGNIGYTL FSSKPVTITV QAWAALHQWG SLWLWSLRLL
Length:190
Mass (Da):21,467
Last modified:February 19, 2014 - v1
Checksum:i732F4D20EB3C7B04
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P12318FCG2A_HUMAN
Low affinity immunoglobulin gamma F...
FCGR2A CD32, FCG2, FCGR2A1, IGFR2
317Annotation score:
F5GX41F5GX41_HUMAN
Low affinity immunoglobulin gamma F...
FCGR2A
137Annotation score:
F5GXY9F5GXY9_HUMAN
Low affinity immunoglobulin gamma F...
FCGR2A
136Annotation score:
V9GY55V9GY55_HUMAN
Low affinity immunoglobulin gamma F...
FCGR2A
86Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590385 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000467525; ENSP00000476495; ENSG00000143226
UCSCiuc057mse.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590385 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliV9GY83
SMRiV9GY83
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiV9GY83
PRIDEiV9GY83

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000467525; ENSP00000476495; ENSG00000143226
UCSCiuc057mse.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000143226.13
HGNCiHGNC:3616 FCGR2A
OpenTargetsiENSG00000143226
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410J9AP Eukaryota
ENOG410YXNK LUCA
GeneTreeiENSGT00760000119130

Miscellaneous databases

ChiTaRSiFCGR2A human

Gene expression databases

BgeeiENSG00000143226 Expressed in 106 organ(s), highest expression level in blood
ExpressionAtlasiV9GY83 baseline and differential

Family and domain databases

Gene3Di2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR003598 Ig_sub2
PfamiView protein in Pfam
PF13895 Ig_2, 2 hits
SMARTiView protein in SMART
SM00409 IG, 2 hits
SM00408 IGc2, 2 hits
SUPFAMiSSF48726 SSF48726, 2 hits
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiV9GY83_HUMAN
AccessioniPrimary (citable) accession number: V9GY83
Entry historyiIntegrated into UniProtKB/TrEMBL: February 19, 2014
Last sequence update: February 19, 2014
Last modified: September 12, 2018
This is version 31 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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