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Protein
Submitted name:

CUB and Sushi multiple domains 2

Gene

Csmd2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
CUB and Sushi multiple domains 2Imported
Gene namesi
Name:Csmd2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:2386401 Csmd2

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei3535 – 3556HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi592 ↔ 619PROSITE-ProRule annotation
Disulfide bondi938 ↔ 965PROSITE-ProRule annotation
Disulfide bondi1316 ↔ 1343PROSITE-ProRule annotation
Disulfide bondi2687 ↔ 2714PROSITE-ProRule annotation
Disulfide bondi2745 ↔ 2772PROSITE-ProRule annotation
Disulfide bondi2803 ↔ 2830PROSITE-ProRule annotation
Disulfide bondi2866 ↔ 2893PROSITE-ProRule annotation
Disulfide bondi2924 ↔ 2951PROSITE-ProRule annotation
Disulfide bondi2985 ↔ 3012PROSITE-ProRule annotation
Disulfide bondi3044 ↔ 3071PROSITE-ProRule annotation
Disulfide bondi3162 ↔ 3189PROSITE-ProRule annotation
Disulfide bondi3220 ↔ 3247PROSITE-ProRule annotation
Disulfide bondi3282 ↔ 3309PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

PaxDbiV9GX34
PeptideAtlasiV9GX34
PRIDEiV9GX34

PTM databases

PhosphoSitePlusiV9GX34

Expressioni

Gene expression databases

BgeeiENSMUSG00000028804 Expressed in 68 organ(s), highest expression level in brain
ExpressionAtlasiV9GX34 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000137727

Structurei

3D structure databases

SMRiV9GX34
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini71 – 179CUBInterPro annotationAdd BLAST109
Domaini182 – 243SushiInterPro annotationAdd BLAST62
Domaini247 – 351CUBInterPro annotationAdd BLAST105
Domaini386 – 447SushiInterPro annotationAdd BLAST62
Domaini450 – 561CUBInterPro annotationAdd BLAST112
Domaini564 – 621SushiInterPro annotationAdd BLAST58
Domaini623 – 731CUBInterPro annotationAdd BLAST109
Domaini734 – 795SushiInterPro annotationAdd BLAST62
Domaini797 – 905CUBInterPro annotationAdd BLAST109
Domaini910 – 967SushiInterPro annotationAdd BLAST58
Domaini969 – 1079CUBInterPro annotationAdd BLAST111
Domaini1082 – 1141SushiInterPro annotationAdd BLAST60
Domaini1143 – 1251CUBInterPro annotationAdd BLAST109
Domaini1254 – 1314SushiInterPro annotationAdd BLAST61
Domaini1316 – 1425CUBInterPro annotationAdd BLAST110
Domaini1428 – 1488SushiInterPro annotationAdd BLAST61
Domaini1490 – 1598CUBInterPro annotationAdd BLAST109
Domaini1601 – 1662SushiInterPro annotationAdd BLAST62
Domaini1664 – 1772CUBInterPro annotationAdd BLAST109
Domaini1778 – 1839SushiInterPro annotationAdd BLAST62
Domaini1841 – 1949CUBInterPro annotationAdd BLAST109
Domaini1952 – 2011SushiInterPro annotationAdd BLAST60
Domaini2013 – 2121CUBInterPro annotationAdd BLAST109
Domaini2124 – 2183SushiInterPro annotationAdd BLAST60
Domaini2185 – 2292CUBInterPro annotationAdd BLAST108
Domaini2295 – 2356SushiInterPro annotationAdd BLAST62
Domaini2358 – 2469CUBInterPro annotationAdd BLAST112
Domaini2469 – 2531SushiInterPro annotationAdd BLAST63
Domaini2532 – 2593SushiInterPro annotationAdd BLAST62
Domaini2594 – 2658SushiInterPro annotationAdd BLAST65
Domaini2659 – 2716SushiInterPro annotationAdd BLAST58
Domaini2717 – 2774SushiInterPro annotationAdd BLAST58
Domaini2775 – 2832SushiInterPro annotationAdd BLAST58
Domaini2833 – 2895SushiInterPro annotationAdd BLAST63
Domaini2896 – 2953SushiInterPro annotationAdd BLAST58
Domaini2957 – 3014SushiInterPro annotationAdd BLAST58
Domaini3015 – 3073SushiInterPro annotationAdd BLAST59
Domaini3074 – 3133SushiInterPro annotationAdd BLAST60
Domaini3134 – 3191SushiInterPro annotationAdd BLAST58
Domaini3192 – 3249SushiInterPro annotationAdd BLAST58
Domaini3253 – 3311SushiInterPro annotationAdd BLAST59
Domaini3312 – 3371SushiInterPro annotationAdd BLAST60

Keywords - Domaini

SushiPROSITE-ProRule annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG4297 Eukaryota
ENOG410XPJ1 LUCA
GeneTreeiENSGT00760000118803
KOiK17495
OMAiYQCNHGF
OrthoDBiEOG091G00EH

Family and domain databases

CDDicd00033 CCP, 28 hits
cd00041 CUB, 14 hits
Gene3Di2.60.120.290, 14 hits
InterProiView protein in InterPro
IPR000859 CUB_dom
IPR035914 Sperma_CUB_dom_sf
IPR035976 Sushi/SCR/CCP_sf
IPR000436 Sushi_SCR_CCP_dom
PfamiView protein in Pfam
PF00431 CUB, 14 hits
PF00084 Sushi, 27 hits
SMARTiView protein in SMART
SM00032 CCP, 28 hits
SM00042 CUB, 14 hits
SUPFAMiSSF49854 SSF49854, 14 hits
SSF57535 SSF57535, 28 hits
PROSITEiView protein in PROSITE
PS01180 CUB, 14 hits
PS50923 SUSHI, 28 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

V9GX34-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPRSRGPEQG CCGCPAVRAR GEIGIWALVP GTGSRWGRPP PPPPPPPPPP
60 70 80 90 100
PLLLLLGWGL LSASAAAGQN CTFHLQGPNG TVESPGFPYG YPNYANCTWT
110 120 130 140 150
ITAEDQHRIQ LVFQSFALEE DFDVLSVFDG PPQAENLRTR LTGFQLPATI
160 170 180 190 200
VSAASTLSLS LISDYAVSAQ GFRASYEVLP SHTCGNPGRL PNGIQQGSTF
210 220 230 240 250
NLGDKVRYSC NPGFFLEGHA VLTCHASSEN SATWDFPLPS CRADDACGGT
260 270 280 290 300
LRGQSGIISS PHFPAEYHNN ADCTWTILAE LGDTIALVFI DFQLEDGYDF
310 320 330 340 350
LEVTGTEGSS LWFTGASLPA PVISSKNWLR LHFTSDGNHR QRGFSAQYQV
360 370 380 390 400
KKQIELKSRG VKLMPSKDNN QKTSVLTQVG VSQGHNMCPD PGIPEKGKRL
410 420 430 440 450
GSDFRLGSSV QFTCNEGYDL QGSKRITCMK VSDMFAAWSD HRPVCRARMC
460 470 480 490 500
DAHLRGPSGI ITSPNFPIQY DNNAHCVWII TALNPAKVIK LAFEEFDLER
510 520 530 540 550
GYDTLTVGDG GQDGDQKTVL YILTGTSVPD LIVSTHHQMW LLFQSDSSGS
560 570 580 590 600
SLGFKASYEE IEQGSCGDPG IPAYGQREGS RFRHGDTLEF ECQPAFELVG
610 620 630 640 650
QKSITCQKNN QWSAKKPGCV FSCFFNFTSP SGIVLSPNYP EDYGNHLHCV
660 670 680 690 700
WLILARPESR IHLAFNDIDV EPQFDFLVIK DGATAEAPVL GTFSGNQLPS
710 720 730 740 750
SITSSGHVAR LEFQTDHSTG KRGFNITFTT FRHNECPDPG VPVNGKRFGD
760 770 780 790 800
SLQLGSSISF LCDEGFLGTQ GSETITCVLK EGSVVWNSAV LRCEAPCGGH
810 820 830 840 850
LTSPSGTILS PGWPGFYKDA LSCAWVIEAQ PGYPIKITFD RFKTEVNYDT
860 870 880 890 900
LEVRDGRTYS APLIGVYHGT QVPQFLISTS NYLYLLFSTD KSHSDIGFQL
910 920 930 940 950
RYETITLQSD HCLDPGIPVN GQRHGNDFYV GALVTFSCDS GYTLSDGEPL
960 970 980 990 1000
ECEPNFQWSH ALPSCEALCG GFIQGSSGTI LSPGFPDFYP NNLNCTWVIE
1010 1020 1030 1040 1050
TSHGKGVFFT FHTFHLESGH DYLLITENGS FSQPLRQLTG SRLPAPISAG
1060 1070 1080 1090 1100
LYGNFTAQVR FISDFSMSYE GFNITFSEYD LEPCEEPEVP AYSIRKGLQF
1110 1120 1130 1140 1150
GVGDTLTFSC FPGYRLEGTA RITCLGGRRR LWSSPLPRCV AECGNSVTGT
1160 1170 1180 1190 1200
QGTLLSPNFP VNYNNNHECI YSIQTQPGKG IQLKAKAFEL AEGDLLKVYD
1210 1220 1230 1240 1250
GTNNSARLLG VFSRSEMLGV TLNSTSSSLW LDFITDAENT SKGFELQFSS
1260 1270 1280 1290 1300
FELIRCEDPG TPQFGYKVHD GGHFAGSSVT FSCDPGYSLR GSEELMCLSG
1310 1320 1330 1340 1350
ERRTWDRPLP TCVAECGGTV RGEVSGQVLS PGYPAPYEHN LNCIWTIEAD
1360 1370 1380 1390 1400
AGCTIGLHFL VFDTEEVHDV LRIWDGPVES GVLLKELSGP MLPKDLHSTF
1410 1420 1430 1440 1450
NSVVLQFSTD FFTSKQGFAI QFSVSTATSC NDPGVPQNGS RSGDSWEAGD
1460 1470 1480 1490 1500
STVFQCDPGY ALQGSAEISC VKIQNRFFWQ PSPPTCIAPC GGDLTGPSGV
1510 1520 1530 1540 1550
ILSPNYPEPY PPGKECDWKV TVSPDYVIAL VFNTFNLEPG YDFLHIYDGR
1560 1570 1580 1590 1600
DSLSPLIGSF YGSQLPSRIE SSSNSLFLAF RSDASVSNAG FVIDYTENPR
1610 1620 1630 1640 1650
ESCFDPGSIK NGTRVGSDLK LGSSVTYYCH GGYEVEGAST LSCILGPDGK
1660 1670 1680 1690 1700
PMWNNPRPVC TAPCGGQYVG SDGVVLSPNY PQNYTSGQTC LYFVTVPKDY
1710 1720 1730 1740 1750
VVFGQFAFFH TALNDIVEVH DGYSQHSRLL SSLSGSHTGE SLPLATSNQV
1760 1770 1780 1790 1800
LIKFSAKGQV SARGFHFVYQ AVPRTSATQC SSVPEPRYGK RLGSDFSVGA
1810 1820 1830 1840 1850
IIRFECNSGY ALQGSPEIEC LPVPGALAQW NVSAPTCVVP CGGNLTERRG
1860 1870 1880 1890 1900
TILSPGFPEP YLNSLNCVWK IMVPEGAGIQ IQVISFVTEQ NWDSLEVFDG
1910 1920 1930 1940 1950
ADNTVTMLGS FSGTTVPALL NSTSNQLYLH FYSDISVSAA GFHLEYKTVG
1960 1970 1980 1990 2000
LSSCPEPAVP SNGVKTGERY LVNDVVSFQC EPGYALQGHA HISCMPGTVR
2010 2020 2030 2040 2050
RWNYPPPLCI AQCGGAVEEM EGVILSPGFP GNYPSNMDCS WKISLPVGFG
2060 2070 2080 2090 2100
AHIQFLNFST EPNHDFLEIR SGPSETSRMM GRFSGSELPG SLLSTSHDSI
2110 2120 2130 2140 2150
VYFHSDHSQN RPGFKLEYQA YELQECPDPE PFANGIVRGA GYNVGQSVTF
2160 2170 2180 2190 2200
ECLPGYQLTG QPVLTCQHGT NRNWDHPLPR CEVPCGGNIT SFNGTVYSPG
2210 2220 2230 2240 2250
YPSPYSSSQD CVWQITVPIG HGVHLNLSLL QIEPFGDYIT VWDGPQQTSL
2260 2270 2280 2290 2300
QLGVFTRSLS KKIAHSSSNQ VLLKFHRDTA TGGIFAIAFS AYPLTKCPPP
2310 2320 2330 2340 2350
TILPNAEVVT ENEEFNIGDI VRYRCLPGFT LVGSEILTCK LGTYLQFEGP
2360 2370 2380 2390 2400
PPICEVHCPT NELLTDSTGV ILSQSYPGSY PQFQTCSWLV RVEPEYNISI
2410 2420 2430 2440 2450
TVEYFLSEKQ YDEFEIFDGP SGQSPLLKAL SGNYSAPLIV TSSSNSVYLR
2460 2470 2480 2490 2500
WSSDHAYNRK GFKIRYSAPY CSLPKAPLHG FILGQTTTQP GGSIHFGCNT
2510 2520 2530 2540 2550
GYRLVGHSMA ICTRHPQGYH LWSEAIPLCQ ALSCGLPDAP KNGIVFGKEY
2560 2570 2580 2590 2600
TVGTKAVYSC NEGYHLQAGA EATAECLDTG LWSNSNVPPQ CVPVTCPDIS
2610 2620 2630 2640 2650
SISVEHGRWR LIFETQYQFQ AQLMLICDPG YYYTGQRVIR CQANGRWSLG
2660 2670 2680 2690 2700
ESMPTCQIIS CGELPTPPSG HRIGTMSVYG ATAIFSCNSG YTLVGSRVRE
2710 2720 2730 2740 2750
CMANGLWSGS EVRCLAGHCG TPEPIVNGHI NGENFNYRGS VVYQCRAGFR
2760 2770 2780 2790 2800
LIGMSVRICQ QDHHWSGKTP FCVPITCGHP GNPVNGLTQG SQFNLNDVVK
2810 2820 2830 2840 2850
FICNPGYIAE GAARSQCLAS GQWSDTLPTC RIINCTDPGH QENSVRQVHT
2860 2870 2880 2890 2900
SGPHRFSFGT TVSYQCNHGF YLLGTPALSC QGDGTWDRPR PQCLLVSCGH
2910 2920 2930 2940 2950
PGSPPHAQMS GDSYIVGAVV RYSCTGKRTL VGNSTRMCGL DGHWTGSLPH
2960 2970 2980 2990 3000
CSGTSTGVCG DPGIPAHGIR LGDSFAPGSV MRFSCDAGHV LRGSSERMCQ
3010 3020 3030 3040 3050
ANGSWSGSQP ECGVISCGNP GTPSNARVVF SDGLVFSSSV VYECREGYYA
3060 3070 3080 3090 3100
TGLLSRHCSV NGTWTGSDPE CTVINCGDPG IPANGIRLGN DFRYNKTVTY
3110 3120 3130 3140 3150
QCVPGYVMES HRVSVLSCTK DRTWNGTKPV CKAIMCKPPQ LIPNGKVVGS
3160 3170 3180 3190 3200
DFTWGSSVSY ACLEGYQLSL PAVLTCEGNG SWTGELPQCF PVFCGDPGVP
3210 3220 3230 3240 3250
PRGRREDRGF SYRSSVSFSC HAPLVLVGSP RRFCQSDGTW SGTQPSCIDP
3260 3270 3280 3290 3300
TLTTCADPGM PQFGIQNSSQ GYQVGSTVLF RCQKGYLLQG STTRTCLPNL
3310 3320 3330 3340 3350
TWSGTPPDCV PHHCKQPETP THANVGALDL PSMGYTLIYS CQEGFSLRGG
3360 3370 3380 3390 3400
SEHRTCKADG SWTGKPPVCL EVRPSGRPIN TAREPMLTQA SVPGDVFAKN
3410 3420 3430 3440 3450
SLWKGAYEYQ GKKQPAMLRV TGFQVANSKV NATMIDHSGV ELHLAGNYKK
3460 3470 3480 3490 3500
EDFRLLLQVY QVTGPVESFV NKFKDDHWAL DGHVSSESSG GTFVYQGSVK
3510 3520 3530 3540 3550
GQGFGQFGFQ RLDLRLLESD PESIGRHFAS NSSSVAAAIL VPFIALIIAG
3560 3570 3580 3590 3600
FVLYLYKHRR RPKVPFNGYA GHENTNVRAT FENPMYDRNI QPTDIMSNEA
3610
EFTVSTVCTA V
Length:3,611
Mass (Da):392,479
Last modified:October 5, 2016 - v2
Checksum:iFA7D92528098FD32
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1Y7VP35A0A1Y7VP35_MOUSE
CUB and Sushi multiple domains 2
Csmd2
302Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL611934 Genomic DNA No translation available.
AL611969 Genomic DNA No translation available.
AL627093 Genomic DNA No translation available.
AL807807 Genomic DNA No translation available.
AL928698 Genomic DNA No translation available.
AL954639 Genomic DNA No translation available.
RefSeqiNP_001268884.1, NM_001281955.1
UniGeneiMm.421342
Mm.491309

Genome annotation databases

EnsembliENSMUST00000184063; ENSMUSP00000138958; ENSMUSG00000028804
GeneIDi329942
KEGGimmu:329942
UCSCiuc033ies.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL611934 Genomic DNA No translation available.
AL611969 Genomic DNA No translation available.
AL627093 Genomic DNA No translation available.
AL807807 Genomic DNA No translation available.
AL928698 Genomic DNA No translation available.
AL954639 Genomic DNA No translation available.
RefSeqiNP_001268884.1, NM_001281955.1
UniGeneiMm.421342
Mm.491309

3D structure databases

SMRiV9GX34
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000137727

PTM databases

PhosphoSitePlusiV9GX34

Proteomic databases

PaxDbiV9GX34
PeptideAtlasiV9GX34
PRIDEiV9GX34

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000184063; ENSMUSP00000138958; ENSMUSG00000028804
GeneIDi329942
KEGGimmu:329942
UCSCiuc033ies.1 mouse

Organism-specific databases

CTDi114784
MGIiMGI:2386401 Csmd2

Phylogenomic databases

eggNOGiKOG4297 Eukaryota
ENOG410XPJ1 LUCA
GeneTreeiENSGT00760000118803
KOiK17495
OMAiYQCNHGF
OrthoDBiEOG091G00EH

Miscellaneous databases

ChiTaRSiCsmd2 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000028804 Expressed in 68 organ(s), highest expression level in brain
ExpressionAtlasiV9GX34 baseline and differential

Family and domain databases

CDDicd00033 CCP, 28 hits
cd00041 CUB, 14 hits
Gene3Di2.60.120.290, 14 hits
InterProiView protein in InterPro
IPR000859 CUB_dom
IPR035914 Sperma_CUB_dom_sf
IPR035976 Sushi/SCR/CCP_sf
IPR000436 Sushi_SCR_CCP_dom
PfamiView protein in Pfam
PF00431 CUB, 14 hits
PF00084 Sushi, 27 hits
SMARTiView protein in SMART
SM00032 CCP, 28 hits
SM00042 CUB, 14 hits
SUPFAMiSSF49854 SSF49854, 14 hits
SSF57535 SSF57535, 28 hits
PROSITEiView protein in PROSITE
PS01180 CUB, 14 hits
PS50923 SUSHI, 28 hits
ProtoNetiSearch...

Entry informationi

Entry nameiV9GX34_MOUSE
AccessioniPrimary (citable) accession number: V9GX34
Entry historyiIntegrated into UniProtKB/TrEMBL: February 19, 2014
Last sequence update: October 5, 2016
Last modified: November 7, 2018
This is version 39 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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