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Protein
Submitted name:

Transforming growth factor beta-1

Gene

TGFB1

Organism
Ophiophagus hannah (King cobra) (Naja hannah)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

GO - Molecular functioni

Keywordsi

Molecular functionGrowth factorSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Transforming growth factor beta-1Imported
Gene namesi
Name:TGFB1Imported
ORF Names:L345_17071Imported
OrganismiOphiophagus hannah (King cobra) (Naja hannah)Imported
Taxonomic identifieri8665 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaSerpentesColubroideaElapidaeElapinaeOphiophagus
Proteomesi
  • UP000018936 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

TopDownProteomicsiV8N6N3

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini51 – 101TGF_BETA_2InterPro annotationAdd BLAST51

Sequence similaritiesi

Belongs to the TGF-beta family.SAAS annotation

Family and domain databases

Gene3Di2.10.90.10, 1 hit
InterProiView protein in InterPro
IPR029034 Cystine-knot_cytokine
IPR001839 TGF-b_C
IPR015615 TGF-beta-rel
PANTHERiPTHR11848 PTHR11848, 1 hit
SUPFAMiSSF57501 SSF57501, 1 hit
PROSITEiView protein in PROSITE
PS51362 TGF_BETA_2, 1 hit

Sequencei

Sequence statusi: Fragment.

V8N6N3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTYKAFNRPS CSSLRFSQSL SLFLVTWGPK LDVVLTKKSC ISKQAVLVSF
60 70 80 90 100
AQVLALYNFH NPSASAAPCC VPDELEPLGI IYYVGRQAKL RKKIRVGLGE
110 120 130 140 150
RLLRSADSVF PPHLLCSPGK GKNNNPPLAK RSRRKQFAAR WQKKINKELK
160 170 180 190 200
FDRGWELSNR IIKPLKDCHA DFGTESRIVE SRRSFQRDVL HMAKLLGESS
210 220 230 240 250
GRRTMPDSLI LDLMGSPNRI NPALDFSLPA QKKKKSPKLH GVNDSCPTLT
260 270 280 290 300
LCSTSSAPLW GQGFFGAHIV LAYNLGKGGV DGLFQLGKQY SSHSTNLACR
310 320 330 340 350
KPAVKGLDVD LVAMGDPDIV ISVRTRRKTF PPSPCLPHPH IREGSSKINV
360 370 380
SFLPLTLMVS AGNSVTANWT GKVPIYPQLS QGQTWAVH
Length:388
Mass (Da):42,838
Last modified:February 19, 2014 - v1
Checksum:i024C02E0D509655E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AZIM01009249 Genomic DNA Translation: ETE57217.1

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AZIM01009249 Genomic DNA Translation: ETE57217.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

TopDownProteomicsiV8N6N3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.10.90.10, 1 hit
InterProiView protein in InterPro
IPR029034 Cystine-knot_cytokine
IPR001839 TGF-b_C
IPR015615 TGF-beta-rel
PANTHERiPTHR11848 PTHR11848, 1 hit
SUPFAMiSSF57501 SSF57501, 1 hit
PROSITEiView protein in PROSITE
PS51362 TGF_BETA_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiV8N6N3_OPHHA
AccessioniPrimary (citable) accession number: V8N6N3
Entry historyiIntegrated into UniProtKB/TrEMBL: February 19, 2014
Last sequence update: February 19, 2014
Last modified: May 10, 2017
This is version 17 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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