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UniProtKB - V6F4Q0 (V6F4Q0_MAGGM)
Protein
Ferric uptake regulation protein
Gene
Fur
Organism
Magnetospirillum gryphiswaldense (strain DSM 6361 / JCM 21280 / NBRC 15271 / MSR-1)
Status
Functioni
Acts as a global negative controlling element, employing Fe2+ as a cofactor to bind the operator of the repressed genes.
ARBA annotationSites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 33 | Manganese 1; via tele nitrogenCombined sources | 1 | |
Metal bindingi | 81 | Manganese 1Combined sources | 1 | |
Metal bindingi | 87 | Manganese 2; via tele nitrogenCombined sources | 1 | |
Metal bindingi | 88 | Manganese 1; via tele nitrogenCombined sources | 1 | |
Metal bindingi | 89 | Manganese 2Combined sources | 1 | |
Metal bindingi | 90 | Manganese 1; via tele nitrogenCombined sources | 1 | |
Metal bindingi | 101 | Manganese 1Combined sources | 1 | |
Metal bindingi | 108 | Manganese 2Combined sources | 1 | |
Metal bindingi | 125 | Manganese 2; via tele nitrogenCombined sources | 1 |
GO - Molecular functioni
- DNA binding Source: UniProtKB-UniRule
- DNA-binding transcription factor activity Source: UniProtKB-UniRule
- metal ion binding Source: UniProtKB-KW
Keywordsi
Molecular function | DNA-bindingUniRule annotationImported, RepressorUniRule annotation |
Biological process | Transcription, Transcription regulationUniRule annotation |
Ligand | IronUniRule annotation, ManganeseCombined sources, Metal-bindingUniRule annotationCombined sources, ZincUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Ferric uptake regulation proteinUniRule annotationARBA annotation |
Gene namesi | Name:FurImported Synonyms:furUniRule annotation ORF Names:MGMSRv2__3137Imported |
Organismi | Magnetospirillum gryphiswaldense (strain DSM 6361 / JCM 21280 / NBRC 15271 / MSR-1)Imported |
Taxonomic identifieri | 431944 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Rhodospirillaceae › Magnetospirillum › |
Proteomesi |
|
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm UniRule annotation
Other locations
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmUniRule annotationInteractioni
Subunit structurei
Homodimer.
UniRule annotationProtein-protein interaction databases
STRINGi | 1430440.MGMSRv2_3137 |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | COG0735, Bacteria |
HOGENOMi | CLU_096072_3_2_5 |
OrthoDBi | 1630127at2 |
Family and domain databases
CDDi | cd07153, Fur_like, 1 hit |
Gene3Di | 1.10.10.10, 1 hit 3.30.1490.190, 1 hit |
InterProi | View protein in InterPro IPR002481, FUR IPR043135, Fur_C IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
PANTHERi | PTHR33202, PTHR33202, 1 hit |
Pfami | View protein in Pfam PF01475, FUR, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
i Sequence
Sequence statusi: Complete.
V6F4Q0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVSRIEQRCI DKGMKMTDQR RVIAQVLSDS ADHPDVEEVY RRATAKDPRI
60 70 80 90 100
SIATVYRTVR LFEEESILER HDFGDGRARY EEAPSEHHDH LIDVNSARVI
110 120 130 140
EFTSPEIEAL QREIARKHGF RLVGHRLELY GVPLTSGGDS DDK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | HG794546 Genomic DNA Translation: CDL00352.1 |
RefSeqi | WP_024081295.1, NZ_CP027526.1 |
Genome annotation databases
EnsemblBacteriai | CDL00352; CDL00352; MGMSRv2__3137 |
KEGGi | mgry:MSR1_28680 mgy:MGMSRv2__3137 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | HG794546 Genomic DNA Translation: CDL00352.1 |
RefSeqi | WP_024081295.1, NZ_CP027526.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
4RAY | X-ray | 1.55 | A/B | 1-143 | [»] | |
4RAZ | X-ray | 1.90 | A/B | 1-143 | [»] | |
4RB0 | X-ray | 1.85 | A/B | 1-143 | [»] | |
4RB1 | X-ray | 2.75 | A/B | 1-143 | [»] | |
4RB2 | X-ray | 2.82 | C/D | 1-143 | [»] | |
4RB3 | X-ray | 2.60 | C/D | 1-143 | [»] | |
SMRi | V6F4Q0 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 1430440.MGMSRv2_3137 |
Genome annotation databases
EnsemblBacteriai | CDL00352; CDL00352; MGMSRv2__3137 |
KEGGi | mgry:MSR1_28680 mgy:MGMSRv2__3137 |
Phylogenomic databases
eggNOGi | COG0735, Bacteria |
HOGENOMi | CLU_096072_3_2_5 |
OrthoDBi | 1630127at2 |
Family and domain databases
CDDi | cd07153, Fur_like, 1 hit |
Gene3Di | 1.10.10.10, 1 hit 3.30.1490.190, 1 hit |
InterProi | View protein in InterPro IPR002481, FUR IPR043135, Fur_C IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
PANTHERi | PTHR33202, PTHR33202, 1 hit |
Pfami | View protein in Pfam PF01475, FUR, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | V6F4Q0_MAGGM | |
Accessioni | V6F4Q0Primary (citable) accession number: V6F4Q0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 19, 2014 |
Last sequence update: | February 19, 2014 | |
Last modified: | January 19, 2022 | |
This is version 57 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |