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Entry version 41 (05 Jun 2019)
Sequence version 1 (19 Feb 2014)
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Protein
Submitted name:

KETtiN (Drosophila actin-binding) homolog

Gene

ketn-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • actin filament binding Source: GO_Central

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
KETtiN (Drosophila actin-binding) homologImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ketn-1Imported
ORF Names:CELE_F54E2.3Imported, F54E2.3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome V

Organism-specific databases

WormBase

More...
WormBasei
F54E2.3e ; CE38607 ; WBGene00004130 ; ketn-1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
V6CLU0

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
V6CLU0

PeptideAtlas

More...
PeptideAtlasi
V6CLU0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00004130 Expressed in 8 organ(s), highest expression level in material anatomical entity

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
V6CLU0 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
6239.F54E2.3a

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini18 – 105Ig-likeInterPro annotationAdd BLAST88
Domaini133 – 220Ig-likeInterPro annotationAdd BLAST88
Domaini303 – 392Ig-likeInterPro annotationAdd BLAST90
Domaini706 – 796Ig-likeInterPro annotationAdd BLAST91
Domaini806 – 893Ig-likeInterPro annotationAdd BLAST88
Domaini937 – 1027Ig-likeInterPro annotationAdd BLAST91
Domaini1065 – 1155Ig-likeInterPro annotationAdd BLAST91
Domaini1199 – 1281Ig-likeInterPro annotationAdd BLAST83
Domaini1462 – 1554Ig-likeInterPro annotationAdd BLAST93
Domaini1594 – 1687Ig-likeInterPro annotationAdd BLAST94
Domaini1728 – 1819Ig-likeInterPro annotationAdd BLAST92
Domaini1992 – 2085Ig-likeInterPro annotationAdd BLAST94
Domaini2126 – 2217Ig-likeInterPro annotationAdd BLAST92
Domaini2258 – 2350Ig-likeInterPro annotationAdd BLAST93
Domaini2391 – 2481Ig-likeInterPro annotationAdd BLAST91
Domaini2522 – 2613Ig-likeInterPro annotationAdd BLAST92
Domaini2654 – 2745Ig-likeInterPro annotationAdd BLAST92
Domaini2787 – 2878Ig-likeInterPro annotationAdd BLAST92
Domaini2919 – 3010Ig-likeInterPro annotationAdd BLAST92
Domaini3051 – 3141Ig-likeInterPro annotationAdd BLAST91
Domaini3182 – 3273Ig-likeInterPro annotationAdd BLAST92
Domaini3314 – 3407Ig-likeInterPro annotationAdd BLAST94
Domaini3448 – 3539Ig-likeInterPro annotationAdd BLAST92
Domaini3584 – 3677Ig-likeInterPro annotationAdd BLAST94
Domaini3720 – 3811Ig-likeInterPro annotationAdd BLAST92
Domaini3821 – 3913Ig-likeInterPro annotationAdd BLAST93
Domaini3962 – 4052Ig-likeInterPro annotationAdd BLAST91
Domaini4098 – 4185Ig-likeInterPro annotationAdd BLAST88
Domaini4472 – 4560Ig-likeInterPro annotationAdd BLAST89
Domaini4571 – 4659Ig-likeInterPro annotationAdd BLAST89
Domaini4678 – 4768Ig-likeInterPro annotationAdd BLAST91
Domaini4798 – 4886Ig-likeInterPro annotationAdd BLAST89

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni396 – 420DisorderedSequence analysisAdd BLAST25
Regioni466 – 501DisorderedSequence analysisAdd BLAST36
Regioni557 – 578DisorderedSequence analysisAdd BLAST22
Regioni598 – 622DisorderedSequence analysisAdd BLAST25
Regioni652 – 696DisorderedSequence analysisAdd BLAST45
Regioni3567 – 3590DisorderedSequence analysisAdd BLAST24
Regioni4319 – 4357DisorderedSequence analysisAdd BLAST39

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1331 – 1351Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi396 – 416PolyampholyteSequence analysisAdd BLAST21
Compositional biasi652 – 690PolarSequence analysisAdd BLAST39
Compositional biasi3567 – 3581PolyampholyteSequence analysisAdd BLAST15

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410KCW9 Eukaryota
ENOG410XTJ8 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000169215

Database of Orthologous Groups

More...
OrthoDBi
184at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 34 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
IPR010939 Titin-rpts

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07679 I-set, 34 hits
PF06582 Titin_Ig-rpts, 5 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00409 IG, 34 hits
SM00408 IGc2, 25 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48726 SSF48726, 34 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50835 IG_LIKE, 32 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 11 potential isoforms that are computationally mapped.Show allAlign All

V6CLU0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPFKQPLGER DAANRVAPTF IRPLADKRAV VGETIILECQ LEGHPDPAIK
60 70 80 90 100
WLKDGHNVSM CPDYRIEEDG LKHRLVIPQV QAADSGRFTA QASNSAGTKQ
110 120 130 140 150
STCILICAPA PTPVPGAKSA VASPAPPQTP VGPSAPIFLK ELRHQPLKPG
160 170 180 190 200
AGVTFEGRVI AVPPPNIEWM KNGKPLQNYR AKIEHDQKTG IISLIIPQMF
210 220 230 240 250
NDDAGEYTIK ATNVHGEAIS GAQLLPREQY DRWFSNEQTR LTKDRKQGLL
260 270 280 290 300
SQTLRPSSVA QKQMQKQGYD TDQGSVDMHW TISESETEPE LSALDARGVG
310 320 330 340 350
TKPIIRTPLR GLRLTEGTDA ILQANIVGNP KPRIQWLFNG RPLQVSGPRM
360 370 380 390 400
QMTYKGSMAV LKISMVTTEE AGDYTVASEN RFGKVESSAR IEVYPLSVPD
410 420 430 440 450
ERRKENQLRE QQERDRQQQQ QALVEASLAR ERQRDAENRR IREEQDRLRV
460 470 480 490 500
LFEREKAERE RLEEERRQLE HEKRLRQQQQ QQLFEREKSE KEERARLEEE
510 520 530 540 550
RRRLEHEKHL RQQQQTQPYN LHYQQHHQPH QAWQDLDLVR RPQYASDEYQ
560 570 580 590 600
EPHYAQIRPH QQQQQHYQQQ QQSPRQEVTH QNLYEQHRRQ QQLIREQQLY
610 620 630 640 650
QHQHQQHQQQ QQQPQEQQQQ RFHHFNQYQQ HIREQHQNTM PVFRQQQPTQ
660 670 680 690 700
VTNGGIKAAN GSAKTANGSA NGSANGSAVH AANGGPSSQQ ARGHEHGAAL
710 720 730 740 750
VNARPPQFLV HPQSVAAKAF ETVTFSAKVV GTPTPSLTWQ KSDGTVIQSG
760 770 780 790 800
GKYKIENGPD GSGRLIIEKV DAHDADMYML VARNDGGSFQ SRFSLNVLQA
810 820 830 840 850
KSPEAPEFTG KFQSTTLYDG DSVKLYCKAA GEGVSFKWFK DNEPISSGGS
860 870 880 890 900
YAVDNKGNET TLHINNATMK EGGWYRCDAT NKHGTTTLKG RVVVNSRQKF
910 920 930 940 950
NGPAHREMIT LRKVDKVERS RTPVNQLQDV SASKSSPKFE GSLQSQQLVE
960 970 980 990 1000
GQSARLEIKY TPVEDPNLRI AWLLNGKGIL ASSRIVTFTD FGIAALEINP
1010 1020 1030 1040 1050
VNVFDQGEYT VVAVNPLGEA RVSANIAVIG HGSFIQQQQS GSQFGGTAYQ
1060 1070 1080 1090 1100
SKGAQAPAGT HLDLPNFHSD LRSQEVFEGQ QIHLETKLTP INDPDLRVVW
1110 1120 1130 1140 1150
LLDGNELPSN DKYRQTLSHG FASLDIPQTS SNDSGLYSCR AFNKLGESEN
1160 1170 1180 1190 1200
QATIIIVPKS DLQQFEQHRQ LDVEDVREIQ FAHSSQDLTP KFLSQIQPFH
1210 1220 1230 1240 1250
CEQELGRSFF EARIQPINDP TLRVSWLKDG QPLPNANRIQ IFQNFGVVSL
1260 1270 1280 1290 1300
SLHPTYPEDA GVYTCVLFNS HGQAQSSAEL TTVWIDTLQL DSKHADSLPI
1310 1320 1330 1340 1350
IGYLDSHQIH IGPQSVERPE EFNSLEAPKF ARELAGKIEV MENERVHFEA
1360 1370 1380 1390 1400
RILPANDVKM TVEWYHNGNP LPAAHRFHPM FDFGYVALDL LYAYPQDSGT
1410 1420 1430 1440 1450
YTLVARNELG EARSNVELVV GTEKVLYLEP HHPEGLERIK ELEQDRRQGI
1460 1470 1480 1490 1500
AEVEDRTCDA APKFLNDLPD IQLNEHENIH VDLRATPVND PTMVIEWFVN
1510 1520 1530 1540 1550
GRPLLTGSRV KTLNEFGFIA LDIKGAIAED SGTYSVRASN LLGEAIRQCV
1560 1570 1580 1590 1600
ITVTPAGQIL SDTQHQESLG KINYLENLNK YGRVEIEDKG PQEPPTFVVP
1610 1620 1630 1640 1650
LQADLGDVEE GEPIHLECQV NPINDNSLKI IWLRDGQSLP HGHRFRTFYD
1660 1670 1680 1690 1700
FGFVSLDILG FYAQDAGTYT CRAENSLGQA ETVATIRCAP KDAILGAVQH
1710 1720 1730 1740 1750
PRSYARIQEI EAPKPAPQEV PDLPHQPPAF VKQLGPAIQC MEGDNVYLEA
1760 1770 1780 1790 1800
QVTPTDDNSL TYEWLVNGQP LMKAHRFVLS QDFGYIALNI LYCYPEDNGT
1810 1820 1830 1840 1850
YTLVVRNRAG EAQSTVDINC GHTGGNFTDS FHPNSLHRIA ELETPIQRAE
1860 1870 1880 1890 1900
PLPDKEKEVP TIAKPLPATI DSVHESQTLH LEAQVTPIDD NTLRYEWLFN
1910 1920 1930 1940 1950
GNPLKASSRY RVLNDFGFVS LDIDYIIAED SGKYTLVVYN SAGRAETSCE
1960 1970 1980 1990 2000
FQVDRLKSIL SDTAHPESLR RIREMEQLQP AKPSDDDAAA QPPVFTQQLT
2010 2020 2030 2040 2050
GPTEPLKEGQ SVHMDCVVQP INDPSLRIEW FHDGRPLMFG SRIRTIHDFG
2060 2070 2080 2090 2100
YVGLEFLHIH PEDTGTYTCK ATNLIGEATT DIFLECKPRR NIYLDTHHES
2110 2120 2130 2140 2150
SWQKIQEIEN RVDEREPTPE LTFQPPTFTE NLADKEDAQE GQSIRLECRL
2160 2170 2180 2190 2200
IPVNDPTMRV TWTRNGQPLP EASRFMPARN FDYVNLDILA LYGEDSGVYT
2210 2220 2230 2240 2250
CKAVSAFGEA ATSCTVKCAA GKSLLLDTMH DASWKRVQEI ENREKLEAVD
2260 2270 2280 2290 2300
AEPEKTAPKF VTQLNSSLGE LQEGVPIHLE AQVEPTNDNQ LTVQWFHNGQ
2310 2320 2330 2340 2350
PLANGHRFRT RHDFGYVALD ILYAFAQDTG EWACVARNSL GEAQTIANFT
2360 2370 2380 2390 2400
VLPRGTIYTD SQHPESWQKI QVLEAPRAAA PEKPDAEHDA PQFIEPLDSI
2410 2420 2430 2440 2450
DRMEFQSAHF QTKVTPQTDP NLRIQWFKDG QPLMNSNRFK LTTDFGYISL
2460 2470 2480 2490 2500
DIAHTVPEDS GVYSVKASNA KGDAEVQAQL TVTGNAVILG DTQHEQSWQK
2510 2520 2530 2540 2550
IQLIEAPRAP GEEEPDVKHG PPKFVTQLHS LDGVVEGQPS HFEAQFIPFS
2560 2570 2580 2590 2600
DPKTSVQWYL NGNPLSASSR RILRNDFGLV SLDLQYTLGE DAGEYSVVVK
2610 2620 2630 2640 2650
NSEGEDRTSG QLSCTTRAAI LGDTQHEQSW QRIQEIEAPR APGAEPEGPV
2660 2670 2680 2690 2700
YEKPSFVQPL QSVGDLPEGS VALLEARLVP VNDPNLRVQW FYNDQPLMES
2710 2720 2730 2740 2750
NWISTSNDFG CVSLRIAPVY ARHTGVYSCK AWNDSGNAVT SANVGVQGSE
2760 2770 2780 2790 2800
GLLLDTSHPA SLQKIQELEA IDKYARLDAP EREYEKPQWV QGFENYENVG
2810 2820 2830 2840 2850
EGQTVTLHGL VEPSGDPHLR LEWLLNGTPL RNANRFRQEY EFGNAILTIV
2860 2870 2880 2890 2900
HVLPHDSGVY TCRAWNTQGE ASTSATVTTA GYEKILYDSQ HPVSWERIQE
2910 2920 2930 2940 2950
LEAPKIVEEI EEIVQKEKPN FLTQLESAEN VPEGVPLHLE STFQPARDPE
2960 2970 2980 2990 3000
LKVVWQKNGQ PLGASQLVQT KHELGWATLD ISSANEDHNG VYTLTITNSE
3010 3020 3030 3040 3050
GEAVSTASIR VAGTGPILGN TRHEESWKRI QILEAPKEAE PEAPAPVYDH
3060 3070 3080 3090 3100
PAITTQIDDK ECNEGDHVHF EALITPVNDP RLQVQWIRNG VPLAHGSKYA
3110 3120 3130 3140 3150
IQQDFGICTL DVAYTYPEDE GVYQLRIWNP EGEAVSSATL KCHGKDAILG
3160 3170 3180 3190 3200
DVQHQESWKR IQEIEAPKQK LEEADPEPKG PPRFIQQLTS PGSLVENQPA
3210 3220 3230 3240 3250
HFEATVEPVD DPTLTINWFL NGEPMSASSR VKMINDFGWV IMDIAQTEPR
3260 3270 3280 3290 3300
DSGEWKCVAK NAAGEAVSTA TIEVQGKEVI LQDSLQPQSL DRIRQIEAGK
3310 3320 3330 3340 3350
PAPEERPDQQ FEAPAIVNAL QVQGALEEGG SAHLQTQFTP VADPSIKVEW
3360 3370 3380 3390 3400
LKDGQPIFHS NRYKMVHDFG FAVLDILHLL KHDAGEYTFR VSNNSGEAST
3410 3420 3430 3440 3450
STSFEVSESS GLILQPQNEQ KAKAVEILED NLRRRPEEIE QELKEATPVF
3460 3470 3480 3490 3500
IEPLSAPVET EEGGRAHFTA RYEPVNDNQL QVQWYHDGRP LKNGSRIKTI
3510 3520 3530 3540 3550
NSFGYVVLEI SPTYPEDNGE YICRAVNRVG EAVTSTKLTC TPKEGIISAT
3560 3570 3580 3590 3600
QLPERMANAG RRIAEIEAPR PAREDAPDAD HGPPKFTSAL AGPPELQEGQ
3610 3620 3630 3640 3650
QAHLECQVTP VADPRLVIEW FHNGQPVNHT NRMKAIHDFG FVVLQLTPAE
3660 3670 3680 3690 3700
PQDSGTWTCR ATNQHGSDEV STELKVVGGG GVSYEWQSTA ERKERITELE
3710 3720 3730 3740 3750
DWIHRPKEDL NLPAVDYPAP SFSQGLTDLG QLNEADATAF VCVLEPIGDP
3760 3770 3780 3790 3800
TLRVQWEHNG HPIPYSNRIS CTNEFGVATL LIKHLIAADA GEYKCVATNV
3810 3820 3830 3840 3850
KGSATSVGKI AVESSTQIDA PQVVQQLVDS VENILEGDSI HLECRVTPIN
3860 3870 3880 3890 3900
DPRLHVEWLR NGAPLPEASR FKPTFEFGFV SLDILYAYPE DNGDYELVVR
3910 3920 3930 3940 3950
NDKGEARSKT KITVLPRPSL DYTSQTHGNQ QDSLESHFKQ HSQAKLQLTA
3960 3970 3980 3990 4000
NDIYNESDKR APEFRTQLQN IGVLEGEFCR FETQVAPIND PYLKVEWFKD
4010 4020 4030 4040 4050
KKPVLLGHRF RSTLDFGFAC LDLLYALPDD TGEYHCVATN RHGQTMISAK
4060 4070 4080 4090 4100
LACQGASHVI TDSQMPQGLR VSNVKKDNKN IYWSEQGGAV QPKQKQAPQF
4110 4120 4130 4140 4150
TIPLRNLQVT ENQPARFECA VTGYPRPKVT WFINGNQCLH GHRFKLNFDG
4160 4170 4180 4190 4200
LHYLTVSKSR ISDAGEVVAI ARNTEGETIS TATLDIFQND DFRQTKLRPA
4210 4220 4230 4240 4250
NFKTSDELRE RELQWQRDTL GSLGPAFEAA PKPDAQKLMH VERAQSPIEP
4260 4270 4280 4290 4300
MESQELIQKF TRPRDDNFYN KLSYVELQKP QFKGMELEEV NLKAGKVEKY
4310 4320 4330 4340 4350
QPPVEEMERV NLKAIPEKDQ QEVGWERPDW AGQDGTSKLP GADEGRFKKL
4360 4370 4380 4390 4400
PTPAPELDVP ARDQVKLKTA KPTRGKDLEA GEKVKLKTEK AKIKEIQQKP
4410 4420 4430 4440 4450
EQPKEEPIVH KDAVQLKTQQ LPKTGIKGDH FTVDREKDLK ETPAVVKPVI
4460 4470 4480 4490 4500
EETRISNKPQ PTKIGQSKQA PPTISQQLKP LQGELGKAAK FVIEFAGAAP
4510 4520 4530 4540 4550
VKVTWLKDGK EIKSTFRTLI TTTPTNSSLH IGRLENSHAG EYTVRLENAA
4560 4570 4580 4590 4600
GTVESLANLT VAPPTTQGKA PDFSARLNDL RIQQNGPAEF SCQIGGEPKP
4610 4620 4630 4640 4650
TIQWFKDGQP LPNDDRFQVV EEGGAYKLKF SNIISTDAGI YEIVAKNGVG
4660 4670 4680 4690 4700
EARCKARLNV NLQKTGKGAE EGPRYEAPRF TSQIQPIVVD EGKGAQFSAQ
4710 4720 4730 4740 4750
FSGFPDPTIR WYRNNEPVKH ADGYEISQSK GEAILRISAA RNEDVAEYKV
4760 4770 4780 4790 4800
EASNPAGKAS SVANLVLTPR SGRIAKSTIS RGGSASYQSS DKAAADSPHF
4810 4820 4830 4840 4850
IAKLSDISAR QGHTVKFSAE VDGNPEPTVQ WQFKGKPISA SNNVKISRDG
4860 4870 4880
KRAILELARV TPDSAGEYQI VIRNDKGAAT SQAKLTLSR
Length:4,889
Mass (Da):546,256
Last modified:February 19, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i24E11F4122EDCF3C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 11 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5PY59Q5PY59_CAEEL
KETtiN (Drosophila actin-binding) h...
ketn-1 CELE_F54E2.3, F54E2.3
4,250Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q8MXD8Q8MXD8_CAEEL
KETtiN (Drosophila actin-binding) h...
ketn-1 CELE_F54E2.3, F54E2.3
4,209Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H2L075H2L075_CAEEL
KETtiN (Drosophila actin-binding) h...
ketn-1 CELE_F54E2.3, F54E2.3
4,131Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q9NL87Q9NL87_CAEEL
KETtiN (Drosophila actin-binding) h...
ketn-1 CELE_F54E2.3, F54E2.3
4,219Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
V6CLT3V6CLT3_CAEEL
KETtiN (Drosophila actin-binding) h...
ketn-1 CELE_F54E2.3, F54E2.3
4,848Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
V6CLP5V6CLP5_CAEEL
KETtiN (Drosophila actin-binding) h...
ketn-1 CELE_F54E2.3, F54E2.3
4,963Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
V6CJB8V6CJB8_CAEEL
KETtiN (Drosophila actin-binding) h...
ketn-1 CELE_F54E2.3, F54E2.3
4,922Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
V6CLU5V6CLU5_CAEEL
KETtiN (Drosophila actin-binding) h...
ketn-1 CELE_F54E2.3, F54E2.3
4,283Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
V6CKH1V6CKH1_CAEEL
KETtiN (Drosophila actin-binding) h...
ketn-1 CELE_F54E2.3, F54E2.3
4,324Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0M7RDU5A0A0M7RDU5_CAEEL
KETtiN (Drosophila actin-binding) h...
ketn-1 CELE_F54E2.3, F54E2.3
3,397Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There is more potential isoformShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
BX284605 Genomic DNA Translation: CDK13527.1

NCBI Reference Sequences

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RefSeqi
NP_001294666.1, NM_001307737.1

Genome annotation databases

Ensembl metazoan genome annotation project

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EnsemblMetazoai
F54E2.3e; F54E2.3e; WBGene00004130

Database of genes from NCBI RefSeq genomes

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GeneIDi
178740

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA Translation: CDK13527.1
RefSeqiNP_001294666.1, NM_001307737.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi6239.F54E2.3a

Proteomic databases

EPDiV6CLU0
PaxDbiV6CLU0
PeptideAtlasiV6CLU0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF54E2.3e; F54E2.3e; WBGene00004130
GeneIDi178740

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
178740
WormBaseiF54E2.3e ; CE38607 ; WBGene00004130 ; ketn-1

Phylogenomic databases

eggNOGiENOG410KCW9 Eukaryota
ENOG410XTJ8 LUCA
GeneTreeiENSGT00940000169215
OrthoDBi184at2759

Gene expression databases

BgeeiWBGene00004130 Expressed in 8 organ(s), highest expression level in material anatomical entity
ExpressionAtlasiV6CLU0 baseline and differential

Family and domain databases

Gene3Di2.60.40.10, 34 hits
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
IPR010939 Titin-rpts
PfamiView protein in Pfam
PF07679 I-set, 34 hits
PF06582 Titin_Ig-rpts, 5 hits
SMARTiView protein in SMART
SM00409 IG, 34 hits
SM00408 IGc2, 25 hits
SUPFAMiSSF48726 SSF48726, 34 hits
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 32 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiV6CLU0_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: V6CLU0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 19, 2014
Last sequence update: February 19, 2014
Last modified: June 5, 2019
This is version 41 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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