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Entry version 65 (12 Aug 2020)
Sequence version 1 (19 Feb 2014)
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Protein
Submitted name:

DotU family type IV / VI secretion system protein

Gene

dotU1_1

Organism
Acinetobacter baumannii
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
DotU family type IV / VI secretion system proteinImported
Submitted name:
DotU family type IV/VI secretion system proteinImported
Submitted name:
TssLImported
Submitted name:
TssL type VI secretion system proteinImported
Submitted name:
Type IV/VI secretion system, DotU family domain proteinImported
Submitted name:
Type VI secretion system protein DotUImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:dotU1_1Imported
Synonyms:tssLImported
ORF Names:A7M90_06200Imported, AB552B1_01835Imported, AB571B5_01387Imported, AB901B6_00782Imported, ABKPCSM17A_02975Imported, BGC29_07520Imported, CPI82_09660Imported, CSB70_1151Imported, DLI67_11185Imported, DLI69_10360Imported, DLI75_18260Imported, E5294_12580Imported, EA686_04965Imported, EWO92_13700Imported, EWO96_13170Imported, EWP49_12645Imported, F4U04_19365Imported, FD887_14630Imported, FGL68_01665Imported, FJU36_12400Imported, FJU42_20245Imported, FJV14_06435Imported, G3N47_16940Imported, GFL19_02540Imported, GNY86_07105Imported, GY154_18920Imported, IX87_03905Imported, LV38_02291Imported, SAMEA104305318_01406Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAcinetobacter baumanniiImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri470 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacterAcinetobacter calcoaceticus/baumannii complex
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000339528 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000429931 Componenti: Unassembled WGS sequence
  • UP000315888 Componenti: Unassembled WGS sequence
  • UP000430725 Componenti: Unassembled WGS sequence
  • UP000326760 Componenti: Unassembled WGS sequence
  • UP000469164 Componenti: Unassembled WGS sequence
  • UP000445311 Componenti: Unassembled WGS sequence
  • UP000252694 Componenti: Unassembled WGS sequence
  • UP000445315 Componenti: Unassembled WGS sequence
  • UP000320149 Componenti: Unassembled WGS sequence
  • UP000257523 Componenti: Chromosome
  • UP000292122 Componenti: Unassembled WGS sequence
  • UP000280073 Componenti: Unassembled WGS sequence
  • UP000431285 Componenti: Unassembled WGS sequence
  • UP000439424 Componenti: Unassembled WGS sequence
  • UP000460330 Componenti: Unassembled WGS sequence
  • UP000179937 Componenti: Unassembled WGS sequence
  • UP000094982 Componenti: Unassembled WGS sequence
  • UP000223291 Componenti: Unassembled WGS sequence
  • UP000028932 Componenti: Chromosome
  • UP000306363 Componenti: Unassembled WGS sequence
  • UP000292081 Componenti: Unassembled WGS sequence
  • UP000307835 Componenti: Unassembled WGS sequence
  • UP000445303 Componenti: Unassembled WGS sequence
  • UP000326007 Componenti: Chromosome
  • UP000076314 Componenti: Unassembled WGS sequence
  • UP000291489 Componenti: Unassembled WGS sequence
  • UP000445320 Componenti: Unassembled WGS sequence
  • UP000320596 Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei217 – 239HelicalSequence analysisAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini35 – 237DotUInterPro annotationAdd BLAST203

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

KEGG Orthology (KO)

More...
KOi
K11892

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.590, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR017732, T4/T6SS_DotU
IPR038522, T4/T6SS_DotU_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09850, DotU, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR03349, IV_VI_DotU, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

V5VEM3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSQSTGAPSL FDDGQIGTGG NNNSQSQVKL QAINLIDLLH DGFYLIFLIR
60 70 80 90 100
NQYVPADPQR FREKILDLLN RFEQQAKKLQ FSADDIHDAK YAFCALIDET
110 120 130 140 150
IVTQQDPSYF NLQNSWLISP LQLSLFGSQL AGYQFFEILE QLRSRGKERL
160 170 180 190 200
AALEVFHYCL LLGFQGKYRI ESIESLNHLV ARVGDEIDYL KGKKVAFSPF
210 220 230 240 250
SAIPDQIRNI IHRELPFFWI LIFLLIFALL TFAGLRFMLN NQNDKALSNY
260
QNVISAPQEQ AHITIYLP
Length:268
Mass (Da):30,726
Last modified:February 19, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i774D190280BDA5AC
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP009257 Genomic DNA Translation: AIL77808.1
KR109191 Genomic DNA Translation: AKR15119.1
KT334324 Genomic DNA Translation: ALD10096.1
CP027178 Genomic DNA Translation: AVI34087.1
CACSHE010000012 Genomic DNA Translation: CAA0176171.1
CACSGY010000006 Genomic DNA Translation: CAA0197635.1
CACSGJ010000010 Genomic DNA Translation: CAA0215719.1
CACSGV010000046 Genomic DNA Translation: CAA0258803.1
VYJD01000001 Genomic DNA Translation: KAA8930262.1
VYJB01000001 Genomic DNA Translation: KAA8936296.1
LRDW01000020 Genomic DNA Translation: KZA24536.1
WGGS01000009 Genomic DNA Translation: MPU13913.1
VYSO01000057 Genomic DNA Translation: MQZ21199.1
WPIP01000037 Genomic DNA Translation: MVM91285.1
WIGZ01000001 Genomic DNA Translation: MVT91205.1
JAAEFR010000052 Genomic DNA Translation: NDM20335.1
JAAGTS010000023 Genomic DNA Translation: NDW71438.1
MDWM01000140 Genomic DNA Translation: ODP68825.1
LYKI01000034 Genomic DNA Translation: OIG70654.1
NXDV01000006 Genomic DNA Translation: PHQ02869.1
CP045541 Genomic DNA Translation: QFV03603.1
RFDI01000181 Genomic DNA Translation: RSR62288.1
SEUD01000008 Genomic DNA Translation: RYL15851.1
SEUE01000007 Genomic DNA Translation: RYL29052.1
SEUG01000005 Genomic DNA Translation: RYL43792.1
UFMQ01000004 Genomic DNA Translation: SST21255.1
SRZJ01000049 Genomic DNA Translation: TGZ05709.1
VAGE01000020 Genomic DNA Translation: TLT61810.1
VHEA01000016 Genomic DNA Translation: TPS03598.1
VHGY01000097 Genomic DNA Translation: TPU59676.1
VHGX01000031 Genomic DNA Translation: TPU79292.1

NCBI Reference Sequences

More...
RefSeqi
WP_000083629.1, NZ_WYAO01000001.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AIL77808; AIL77808; IX87_03905
AKQ27366; AKQ27366; ACX60_11610
AMN01089; AMN01089; AZE33_07810
BAP67168; BAP67168; IOMTU433_2390
KMV13397; KMV13397; AB988_2814
KQD92049; KQD92049; APD31_09660
KUI78037; KUI78037; AQ480_00555
KZA24536; KZA24536; LV38_02291
ODP68825; ODP68825; BGC29_07520

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
abau:IX87_03905
abk:LX00_06475

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|470.1289.peg.1223

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009257 Genomic DNA Translation: AIL77808.1
KR109191 Genomic DNA Translation: AKR15119.1
KT334324 Genomic DNA Translation: ALD10096.1
CP027178 Genomic DNA Translation: AVI34087.1
CACSHE010000012 Genomic DNA Translation: CAA0176171.1
CACSGY010000006 Genomic DNA Translation: CAA0197635.1
CACSGJ010000010 Genomic DNA Translation: CAA0215719.1
CACSGV010000046 Genomic DNA Translation: CAA0258803.1
VYJD01000001 Genomic DNA Translation: KAA8930262.1
VYJB01000001 Genomic DNA Translation: KAA8936296.1
LRDW01000020 Genomic DNA Translation: KZA24536.1
WGGS01000009 Genomic DNA Translation: MPU13913.1
VYSO01000057 Genomic DNA Translation: MQZ21199.1
WPIP01000037 Genomic DNA Translation: MVM91285.1
WIGZ01000001 Genomic DNA Translation: MVT91205.1
JAAEFR010000052 Genomic DNA Translation: NDM20335.1
JAAGTS010000023 Genomic DNA Translation: NDW71438.1
MDWM01000140 Genomic DNA Translation: ODP68825.1
LYKI01000034 Genomic DNA Translation: OIG70654.1
NXDV01000006 Genomic DNA Translation: PHQ02869.1
CP045541 Genomic DNA Translation: QFV03603.1
RFDI01000181 Genomic DNA Translation: RSR62288.1
SEUD01000008 Genomic DNA Translation: RYL15851.1
SEUE01000007 Genomic DNA Translation: RYL29052.1
SEUG01000005 Genomic DNA Translation: RYL43792.1
UFMQ01000004 Genomic DNA Translation: SST21255.1
SRZJ01000049 Genomic DNA Translation: TGZ05709.1
VAGE01000020 Genomic DNA Translation: TLT61810.1
VHEA01000016 Genomic DNA Translation: TPS03598.1
VHGY01000097 Genomic DNA Translation: TPU59676.1
VHGX01000031 Genomic DNA Translation: TPU79292.1
RefSeqiWP_000083629.1, NZ_WYAO01000001.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiAIL77808; AIL77808; IX87_03905
AKQ27366; AKQ27366; ACX60_11610
AMN01089; AMN01089; AZE33_07810
BAP67168; BAP67168; IOMTU433_2390
KMV13397; KMV13397; AB988_2814
KQD92049; KQD92049; APD31_09660
KUI78037; KUI78037; AQ480_00555
KZA24536; KZA24536; LV38_02291
ODP68825; ODP68825; BGC29_07520
KEGGiabau:IX87_03905
abk:LX00_06475
PATRICifig|470.1289.peg.1223

Phylogenomic databases

KOiK11892

Family and domain databases

Gene3Di1.25.40.590, 1 hit
InterProiView protein in InterPro
IPR017732, T4/T6SS_DotU
IPR038522, T4/T6SS_DotU_sf
PfamiView protein in Pfam
PF09850, DotU, 1 hit
TIGRFAMsiTIGR03349, IV_VI_DotU, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiV5VEM3_ACIBA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: V5VEM3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 19, 2014
Last sequence update: February 19, 2014
Last modified: August 12, 2020
This is version 65 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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