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Entry version 34 (29 Sep 2021)
Sequence version 1 (22 Jan 2014)
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Protein
Submitted name:

WD domain, G-beta repeat-containing protein

Gene

BN1205_049540

Organism
Toxoplasma gondii (strain ATCC 50861 / VEG)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
WD domain, G-beta repeat-containing proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:BN1205_049540Imported, TGVEG_263360Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiToxoplasma gondii (strain ATCC 50861 / VEG)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri432359 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaSarAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaSarcocystidaeToxoplasma
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002226 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Partially assembled WGS sequence

Organism-specific databases

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
ToxoDB:TGVEG_263360

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

PTM databases

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
V4ZHR6

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
5811.TGME49_063360

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati955 – 988WDPROSITE-ProRule annotationAdd BLAST34

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 97DisorderedSequence analysisAdd BLAST97
Regioni174 – 202DisorderedSequence analysisAdd BLAST29
Regioni219 – 248DisorderedSequence analysisAdd BLAST30
Regioni387 – 457DisorderedSequence analysisAdd BLAST71
Regioni530 – 577DisorderedSequence analysisAdd BLAST48
Regioni658 – 770DisorderedSequence analysisAdd BLAST113
Regioni785 – 830DisorderedSequence analysisAdd BLAST46
Regioni852 – 891DisorderedSequence analysisAdd BLAST40
Regioni915 – 940DisorderedSequence analysisAdd BLAST26
Regioni1298 – 1337DisorderedSequence analysisAdd BLAST40
Regioni1442 – 1463DisorderedSequence analysisAdd BLAST22

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi70 – 87Basic and acidic residuesSequence analysisAdd BLAST18
Compositional biasi176 – 200Basic and acidic residuesSequence analysisAdd BLAST25
Compositional biasi533 – 565Polar residuesSequence analysisAdd BLAST33
Compositional biasi659 – 673Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi682 – 739Basic and acidic residuesSequence analysisAdd BLAST58
Compositional biasi785 – 804Polar residuesSequence analysisAdd BLAST20
Compositional biasi918 – 938Basic and acidic residuesSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

RepeatARBA annotation, WD repeatPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0283, Eukaryota

Identification of Orthologs from Complete Genome Data

More...
OMAi
PWREPSC

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.130.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR036322, WD40_repeat_dom_sf
IPR040324, WDR44/Dgr2

The PANTHER Classification System

More...
PANTHERi
PTHR14221, PTHR14221, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00320, WD40, 6 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50978, SSF50978, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50082, WD_REPEATS_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

V4ZHR6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQPGKSLSHA GRRRQQRQLE ASPPPTSRVP ARQPPRRGMF IPACSSGDPE
60 70 80 90 100
AAPQPFLGGE ASHFPGRSSE NGLRPRKTER VSRNGEPIFD PDPEPLLSGI
110 120 130 140 150
KRERMQACSG LAAAFLDLEG HFHIRSTRAS ELGEEQLRLF SRLQEGRSRP
160 170 180 190 200
WREPSCDVSA ATHSSFCAQN PEKGVGEAAE LERTTSPACR ERRTGGEEEN
210 220 230 240 250
VSDEEFYDAT DACDVARDAP ELSFSPRRSP ASARPAQGGH DEEATSSCFE
260 270 280 290 300
GERSWPLLKR REHGDASAFF TTREGRSTES ECSDARGRQR SAYDQARVVR
310 320 330 340 350
QCSFTTAVEA YFPTADKESS VGGRLLSRRS SSVSSLEEGV HTLYRDAGRR
360 370 380 390 400
GLASEKGSEE LRNSVATPRG EFLAAFDATG LRFQQHNVES RQEKIEQENE
410 420 430 440 450
HGRHEDTAEG VTPVDTQGKE SRDSRAGCGR EKIDESIGSA AEESSRVPGD
460 470 480 490 500
RETNGLPDGE LRHCDCSESP AASPFASSAV STSVAPALSR FVSLGSSGSQ
510 520 530 540 550
MLRSGVSSVS LPSKRTWMTR SVNAVKRLGG RRQLSGESTT STRTNLSATG
560 570 580 590 600
ASSRMVTTDG KTATSAVPRS GGRGAQHAGA DYAGLHPFPA VLKRSVTKGN
610 620 630 640 650
KHQPPLSEVW CVRAIETGDR AALWATAISP AGDWLAAAGQ TGVISLWSVP
660 670 680 690 700
SLCVSALSRR GRGEDKRGRK FAGSLTGKGD SERPLPQRDG AHLSMKDADK
710 720 730 740 750
NEMTHAETVH LEEVDGTRRG RTFREMRTRG SHDGGRSTAT DEACEQCQSD
760 770 780 790 800
PGTLASHAPD GGTPPQEGHE NEIVCRPAHM RASSLPVSLS SASNHRSSPS
810 820 830 840 850
SRLACASHLR RRNPRGVRTP DSGARPLRPF ASLPGERVGV VGRGKAAVCG
860 870 880 890 900
FPAERRTRSD ETSTPAAAAA AEETNGSEAP ACGGDTPESV RAKAPVGAGA
910 920 930 940 950
KKAFSRGLRA HTEEGVASLL GRGDREAGRE KREEANASRR QATPWFISNR
960 970 980 990 1000
PTLCLTGHSA AIIQLVWAPT QKAALLLSAS LDKTVRLWWP AKQPEAVAVL
1010 1020 1030 1040 1050
RCRDWPTSVA FHPTFKNVVF TGCLDATVQV WRLFPVSDSS GARAREDRGR
1060 1070 1080 1090 1100
REEGSRQKEG KTLWDARVVE YLKVTELVTA ISLSPNGSVL AVGFRNGTIA
1110 1120 1130 1140 1150
FYDAQTLKFR NELDCRNRKG KFSKGRKVTS LEWHASGLAL CVTTNDSRIR
1160 1170 1180 1190 1200
IFRATDLSCV AKFKGHINEQ IMLRANYTNE GTGLVCGSEN GWICCWNVAD
1210 1220 1230 1240 1250
PRSSIADGVE RRFRGNVLSS KLSIPATNRR PTNANFAGIK AFTELLTCSL
1260 1270 1280 1290 1300
VAPASFASAL VSRIGVHPLG SPSAKQTGSR RLSLRKFVFR SDSGVSAGLR
1310 1320 1330 1340 1350
GVQGETTGRS HSKSNLDRLS HAPPGDRQET VTDGFSSGCL PAQDSALPRD
1360 1370 1380 1390 1400
PRCLLLPPSS CGVADSRPFN VGKGELVDRQ GSHLAALKAM CLPKYGRGSP
1410 1420 1430 1440 1450
SGTLGSLPAH ASEGGEEDLD ARGRSLDKVD FLGKSSLFSS VNRPGSDSPV
1460 1470 1480 1490 1500
LYNGGSEAPY SRPPSECGSA GFALAAPGLS GFPAKDLPLK AESPSSGAST
1510 1520 1530 1540 1550
PGRGDYGGAF CSYLDERRKN QEGDRYYHEG EELHIALPAS VYREECRQRS
1560 1570 1580
SSTSLPLVVV AGSHHGKLRI FVNFGQELRN F
Length:1,581
Mass (Da):169,937
Last modified:January 22, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAAE0C7EF1133F425
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
LN714497 Genomic DNA Translation: CEL74115.1
AAYL02000153 Genomic DNA Translation: ESS31872.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
ESS31872; ESS31872; TGVEG_263360

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LN714497 Genomic DNA Translation: CEL74115.1
AAYL02000153 Genomic DNA Translation: ESS31872.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi5811.TGME49_063360

PTM databases

SwissPalmiV4ZHR6

Genome annotation databases

EnsemblProtistsiESS31872; ESS31872; TGVEG_263360

Organism-specific databases

VEuPathDBiToxoDB:TGVEG_263360

Phylogenomic databases

eggNOGiKOG0283, Eukaryota
OMAiPWREPSC

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR036322, WD40_repeat_dom_sf
IPR040324, WDR44/Dgr2
PANTHERiPTHR14221, PTHR14221, 3 hits
SMARTiView protein in SMART
SM00320, WD40, 6 hits
SUPFAMiSSF50978, SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS50082, WD_REPEATS_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiV4ZHR6_TOXGV
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: V4ZHR6
Secondary accession number(s): A0A0F7V1U9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 22, 2014
Last sequence update: January 22, 2014
Last modified: September 29, 2021
This is version 34 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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