ID   V4RSF5_9CAUL            Unreviewed;       655 AA.
AC   V4RSF5;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Histidine kinase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=ABENE_03135 {ECO:0000313|EMBL:ESQ94098.1};
OS   Asticcacaulis benevestitus DSM 16100 = ATCC BAA-896.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC   Caulobacteraceae; Asticcacaulis.
OX   NCBI_TaxID=1121022 {ECO:0000313|EMBL:ESQ94098.1, ECO:0000313|Proteomes:UP000017837};
RN   [1] {ECO:0000313|EMBL:ESQ94098.1, ECO:0000313|Proteomes:UP000017837}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16100 {ECO:0000313|EMBL:ESQ94098.1,
RC   ECO:0000313|Proteomes:UP000017837};
RX   PubMed=24463524; DOI=10.1038/nature12900;
RA   Jiang C., Brown P.J., Ducret A., Brun Y.V.;
RT   "Sequential evolution of bacterial morphology by co-option of a
RT   developmental regulator.";
RL   Nature 506:489-493(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ESQ94098.1}.
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DR   EMBL; AWGB01000005; ESQ94098.1; -; Genomic_DNA.
DR   RefSeq; WP_018081407.1; NZ_AWGB01000005.1.
DR   AlphaFoldDB; V4RSF5; -.
DR   STRING; 1121022.GCA_000376105_01740; -.
DR   PATRIC; fig|1121022.4.peg.622; -.
DR   eggNOG; COG5001; Bacteria.
DR   Proteomes; UP000017837; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017837};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        43..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        68..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        108..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        133..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        183..204
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          259..392
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          401..651
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   655 AA;  72511 MW;  EE9E5A08868065B0 CRC64;
     MKISSLKIGH LKSAATALFA LFRVPTDNME LARAQYSAFT KQIPLLYVLL SINTIAVAFT
     YAPLAPPWLG IYIPAMLCVL CVARLIHWAR QSRTELDDDN VLHQLRRTNK LAIIIAAGFT
     AWALSLYDYG DAYAHAHVSF YMAVTVIGCI FCLMHLRSAA ISVTLVVNIP YITFFLMQPQ
     ISLKAMALNL TFVCAAMITV LMIYSRDFAR LVASRGETHR LSDENFRIAN LDSLTQLANR
     RLFFAELERQ YASALIDGRG FAIGIIDLDG FKPINDTYGH TTGDRVLVEA AQRIRQACAD
     DLILARLGGD EFGFIASRNP APEDLQALSD SITGLLRLPF SIGSSSVQLG CSIGVAFYPQ
     SADTPDVLFE RADYALYHAK RHHRGDMVVF SEEHEEEIRS HGIIERTLQN ADLDAELSMI
     YQPIVDTTTG ETIAFEALAR WHSPTLGFVG PDQFIPVAER AGLIRRVTRT LLKKALAALK
     TWPADMRMSF NLSAHDLSDS ESVVQIIALI NRSGINPKRL DFEITETSVS HDFVQARAAV
     TTFKALGVGI SLDDFGTGYS SLSHVHSLPL DKIKVDRSFV TDINTNPVSL KIVKSLTALC
     ADMDLECIIE GVETEAQLAT LMELGCRRVQ GYYFARPMPE CDVLPYLDLA TAKRA
//