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Protein

5'-deoxynucleotidase YfbR

Gene

yfbR

Organism
Salmonella enterica subsp. indica serovar 6,14,25:z10:1,(2),7 str. 1121
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.UniRule annotationSAAS annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

A 2'-deoxyribonucleoside 5'-monophosphate + H2O = a 2'-deoxyribonucleoside + phosphate.UniRule annotationSAAS annotation

Cofactori

a divalent metal cationUniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei18Appears to be important in orienting the phosphate for catalysisUniRule annotation1
Metal bindingi33Divalent metal cation; via tele nitrogenUniRule annotation1
Binding sitei33SubstrateUniRule annotation1
Metal bindingi68Divalent metal cation; via tele nitrogenUniRule annotation1
Metal bindingi69Divalent metal cationUniRule annotation1
Binding sitei69SubstrateUniRule annotation1
Metal bindingi137Divalent metal cationUniRule annotation1
Binding sitei137SubstrateUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation
LigandMetal-bindingUniRule annotationSAAS annotation, Nucleotide-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
5'-deoxynucleotidase YfbRUniRule annotation (EC:3.1.3.89UniRule annotation)
Alternative name(s):
5'-deoxyribonucleotidaseUniRule annotation
Nucleoside 5'-monophosphate phosphohydrolaseUniRule annotation
Gene namesi
Name:yfbRUniRule annotation
ORF Names:SEI61121_03599Imported
OrganismiSalmonella enterica subsp. indica serovar 6,14,25:z10:1,(2),7 str. 1121Imported
Taxonomic identifieri1173950 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000017304 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homodimer.UniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 142HDInterPro annotationAdd BLAST113

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni18 – 19Substrate bindingUniRule annotation2
Regioni77 – 80Substrate bindingUniRule annotation4

Sequence similaritiesi

Belongs to the 5DNU family.UniRule annotationSAAS annotation

Family and domain databases

HAMAPiMF_01100 5DNU, 1 hit
InterProiView protein in InterPro
IPR003607 HD/PDEase_dom
IPR006674 HD_domain
IPR039356 Nucleoside_monoPase
IPR022971 YfbR
PANTHERiPTHR11845 PTHR11845, 1 hit
PfamiView protein in Pfam
PF13023 HD_3, 1 hit
SMARTiView protein in SMART
SM00471 HDc, 1 hit
PROSITEiView protein in PROSITE
PS51831 HD, 1 hit

Sequencei

Sequence statusi: Complete.

V1HC57-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKQSHFFAHL SRMKLINRWP LMRNVRTENV SEHSLQVAMV AHALAAIKNR
60 70 80 90 100
KFGGQLNAER IALLAMYHDA SEVLTGDLPT PVKYFNSQIA QEYKAIEKIA
110 120 130 140 150
QQKLVDMAPD ELRDIFAPLI DENAWSEEEQ AIVKQADALC AYLKCLEELS
160 170 180 190
AGNNEFRLAK TRLEKTLELR RSQEMDYFMA VFVPSFHLSL DEISQDSPL
Length:199
Mass (Da):22,796
Last modified:January 22, 2014 - v1
Checksum:i7193A20D8B21167E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AOXI01000005 Genomic DNA Translation: ESE87395.1
RefSeqiWP_020437474.1, NZ_AOXI01000005.1

Genome annotation databases

EnsemblBacteriaiESE87395; ESE87395; SEI61121_03599
PATRICifig|1173950.3.peg.755

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AOXI01000005 Genomic DNA Translation: ESE87395.1
RefSeqiWP_020437474.1, NZ_AOXI01000005.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiESE87395; ESE87395; SEI61121_03599
PATRICifig|1173950.3.peg.755

Family and domain databases

HAMAPiMF_01100 5DNU, 1 hit
InterProiView protein in InterPro
IPR003607 HD/PDEase_dom
IPR006674 HD_domain
IPR039356 Nucleoside_monoPase
IPR022971 YfbR
PANTHERiPTHR11845 PTHR11845, 1 hit
PfamiView protein in Pfam
PF13023 HD_3, 1 hit
SMARTiView protein in SMART
SM00471 HDc, 1 hit
PROSITEiView protein in PROSITE
PS51831 HD, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiV1HC57_SALCE
AccessioniPrimary (citable) accession number: V1HC57
Entry historyiIntegrated into UniProtKB/TrEMBL: January 22, 2014
Last sequence update: January 22, 2014
Last modified: September 12, 2018
This is version 22 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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