UniProtKB - U5XJZ2 (U5XJZ2_HUMAN)
Protein
Submitted name:
LILRA6
Gene
LILRA6
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: LILRA6ImportedSubmitted name: Leukocyte immunoglobulin-like receptor subfamily A member 6Imported |
Gene namesi | Name:LILRA6Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:15495, LILRA6 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 23 | Sequence analysisAdd BLAST | 23 | |
ChainiPRO_5014109211 | 24 – 481 | Sequence analysisAdd BLAST | 458 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 49 ↔ 98 | UniRule annotation | ||
Disulfide bondi | 144 ↔ 196 | UniRule annotation |
Keywords - PTMi
Disulfide bondUniRule annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 27 – 98 | Ig-likeInterPro annotationAdd BLAST | 72 | |
Domaini | 225 – 314 | Ig-likeInterPro annotationAdd BLAST | 90 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 59 – 78 | DisorderedSequence analysisAdd BLAST | 20 | |
Regioni | 408 – 439 | DisorderedSequence analysisAdd BLAST | 32 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 60 – 77 | PolyampholyteSequence analysisAdd BLAST | 18 |
Keywords - Domaini
SignalSequence analysisPhylogenomic databases
OrthoDBi | 1000446at2759 |
Family and domain databases
Gene3Di | 2.60.40.10, 4 hits |
InterProi | View protein in InterPro IPR016332, A1B_glyco/leuk_Ig-like_rcpt IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003599, Ig_sub IPR003598, Ig_sub2 IPR013151, Immunoglobulin |
Pfami | View protein in Pfam PF00047, ig, 1 hit PF13895, Ig_2, 1 hit |
PIRSFi | PIRSF001979, Alpha_1B_glycoprot_prd, 1 hit |
SMARTi | View protein in SMART SM00409, IG, 3 hits SM00408, IGc2, 3 hits |
SUPFAMi | SSF48726, SSF48726, 4 hits |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 2 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 18 potential isoforms that are computationally mapped.Show allAlign All
U5XJZ2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTPALTALLC LGLSLGPRTR VQAGPFPKPT LWAEPGSVIS WGSPVTIWCQ
60 70 80 90 100
GSLEAQEYQL DKEGSPEPWD RNNPLEPKNK ARFSIPSMTQ HHAGRYRCHY
110 120 130 140 150
YSSAGWSEPS DPLELVMTGF YNKPTLSALP SPVVASGGNM TLRCGSQKGY
160 170 180 190 200
HHFVLMKEGE HQLPRTLDSQ QLHSGGFQAL FPVGPVTPSH RWRFTCYYYY
210 220 230 240 250
TNTPWVWSHP SDPLEILPSG VSRKPSLLTL QGPVLAPGQS LTLQCGSDVG
260 270 280 290 300
YDRFVLYKEG ERDFLQRPGQ QPQAGLSQAN FTLGPVSPSH GGQYRCYGAH
310 320 330 340 350
NLSSEWSAPS DPLNILMAGQ IYDTVSLSAQ PGPTVASGEN VTLLCQSRGY
360 370 380 390 400
FDTFLLTKEG AAHPPLRLRS MYGAHKYQAE FPMSPVTSAH AGTYRCYGSR
410 420 430 440 450
SSNPHLLSHP SEPLELMVSG PSGGSSLPPT GPPSTPASHA KDYTVENLIR
460 470 480
MGMAGLVLVF LGILLFEAQH SQRNPQDAAG R
Computationally mapped potential isoform sequencesi
There are 18 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ6PI73 | LIRA6_HUMAN | Leukocyte immunoglobulin-like recep... | LILRA6 ILT8 | 481 | Annotation score: | ||
A0A0G2JPR9 | A0A0G2JPR9_HUMAN | Leukocyte immunoglobulin-like recep... | LILRA6 | 648 | Annotation score: | ||
A0A0G2JPW1 | A0A0G2JPW1_HUMAN | Leukocyte immunoglobulin-like recep... | LILRA6 | 632 | Annotation score: | ||
A0A0G2JQ25 | A0A0G2JQ25_HUMAN | Leukocyte immunoglobulin-like recep... | LILRA6 | 632 | Annotation score: | ||
A0A0G2JMN6 | A0A0G2JMN6_HUMAN | Leukocyte immunoglobulin-like recep... | LILRA6 | 504 | Annotation score: | ||
A0A0G2JN43 | A0A0G2JN43_HUMAN | Leukocyte immunoglobulin-like recep... | LILRA6 | 481 | Annotation score: | ||
A0A0G2JPA2 | A0A0G2JPA2_HUMAN | Leukocyte immunoglobulin-like recep... | LILRA6 | 504 | Annotation score: | ||
A0A0G2JPY1 | A0A0G2JPY1_HUMAN | Leukocyte immunoglobulin-like recep... | LILRA6 | 481 | Annotation score: | ||
A0A0G2JQ24 | A0A0G2JQ24_HUMAN | Leukocyte immunoglobulin-like recep... | LILRA6 | 512 | Annotation score: | ||
A0A0G2JMX0 | A0A0G2JMX0_HUMAN | Leukocyte immunoglobulin-like recep... | LILRA6 | 382 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU457734 Genomic DNA No translation available. KC918867 mRNA Translation: AGZ61991.1 |
RefSeqi | XP_016885726.1, XM_017030237.1 |
Genome annotation databases
Ensembli | ENST00000621450; ENSP00000481288; ENSG00000275584 |
UCSCi | uc032imr.2, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU457734 Genomic DNA No translation available. KC918867 mRNA Translation: AGZ61991.1 |
RefSeqi | XP_016885726.1, XM_017030237.1 |
3D structure databases
SMRi | U5XJZ2 |
ModBasei | Search... |
Genome annotation databases
Ensembli | ENST00000621450; ENSP00000481288; ENSG00000275584 |
UCSCi | uc032imr.2, human |
Organism-specific databases
HGNCi | HGNC:15495, LILRA6 |
GenAtlasi | Search... |
Phylogenomic databases
OrthoDBi | 1000446at2759 |
Miscellaneous databases
BioGRID-ORCSi | 79168, 18 hits in 812 CRISPR screens |
GenomeRNAii | 79168 |
Family and domain databases
Gene3Di | 2.60.40.10, 4 hits |
InterProi | View protein in InterPro IPR016332, A1B_glyco/leuk_Ig-like_rcpt IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003599, Ig_sub IPR003598, Ig_sub2 IPR013151, Immunoglobulin |
Pfami | View protein in Pfam PF00047, ig, 1 hit PF13895, Ig_2, 1 hit |
PIRSFi | PIRSF001979, Alpha_1B_glycoprot_prd, 1 hit |
SMARTi | View protein in SMART SM00409, IG, 3 hits SM00408, IGc2, 3 hits |
SUPFAMi | SSF48726, SSF48726, 4 hits |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | U5XJZ2_HUMAN | |
Accessioni | U5XJZ2Primary (citable) accession number: U5XJZ2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | January 22, 2014 |
Last sequence update: | January 22, 2014 | |
Last modified: | December 2, 2020 | |
This is version 49 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |