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Protein

Xylose isomerase

Gene

xylA

Organism
Clostridium autoethanogenum DSM 10061
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei101UniRule annotation1
Active sitei104UniRule annotation1
Metal bindingi232Magnesium 1UniRule annotation1
Metal bindingi268Magnesium 1UniRule annotation1
Metal bindingi268Magnesium 2UniRule annotation1
Metal bindingi271Magnesium 2UniRule annotation1
Metal bindingi296Magnesium 1UniRule annotation1
Metal bindingi307Magnesium 2UniRule annotation1
Metal bindingi309Magnesium 2UniRule annotation1
Metal bindingi339Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processCarbohydrate metabolism, Xylose metabolismUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotationSAAS annotation (EC:5.3.1.5UniRule annotationSAAS annotation)
Gene namesi
Name:xylAUniRule annotation
ORF Names:CAETHG_3932Imported
OrganismiClostridium autoethanogenum DSM 10061Imported
Taxonomic identifieri1341692 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000017590 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliU5S3A4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili112 – 132Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

KOiK01805
OrthoDBiPOG091H07LC

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013452 Xylose_isom_bac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02630 xylose_isom_A, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

U5S3A4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKEYFNNVSK INYEGPDSKN PYSFKYYNPD EVIGGKKMRD HLRFSMSYWH
60 70 80 90 100
TLTANGTDQF GSGTMVRPWD NVNDKMELAK ARMEAAFEFM NKLDIDYFCF
110 120 130 140 150
HDRDIAPEGK DLAETNKNLD EIVAMCKDLM KKNNKKLLWG TANLFNNPRF
160 170 180 190 200
VHGAGTTCNA NVYAYSAAQL KKAIEVTNEL GGENYVFWGG REGYETLLNT
210 220 230 240 250
DMGFEMDNFA RILQMAVDYA KKIGFKGQFL IEPKPKEPTK HQYDFDVATV
260 270 280 290 300
LGFLRKYKLE DYFKINIEAN HATLAGHTFQ HEICLARNNN ALGSLDANQG
310 320 330 340 350
DPHLGWDTDQ FPTNVYDTTL SMYEVLKNGG IAPGGLNFDA KVRRASFEPE
360 370 380 390 400
DLFLAYIAGM DSFAKGLRVA YKLLQDAPIE NFIKERYSSF STGIGKDIVD
410 420 430 440
GKVGFDELEK YALENNVINN KSGRQEYLES VVNQYILEDK
Length:440
Mass (Da):50,112
Last modified:January 22, 2014 - v1
Checksum:iA76171A640A04875
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP006763 Genomic DNA Translation: AGY78133.1
RefSeqiWP_013238479.1, NZ_CP012395.1

Genome annotation databases

EnsemblBacteriaiAGY78133; AGY78133; CAETHG_3932
GeneIDi33106134
KEGGicah:CAETHG_3932
PATRICifig|1341692.11.peg.3955

Similar proteinsi

Entry informationi

Entry nameiU5S3A4_9CLOT
AccessioniPrimary (citable) accession number: U5S3A4
Entry historyiIntegrated into UniProtKB/TrEMBL: January 22, 2014
Last sequence update: January 22, 2014
Last modified: June 20, 2018
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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