Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 56 (29 Sep 2021)
Sequence version 1 (11 Dec 2013)
Previous versions | rss
Add a publicationFeedback
Protein

Patronin (microtubule-binding protein) homolog

Gene

ptrn-1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for microtubule stability and anchorage by binding to the minus ends of microtubules (PubMed:25437544, PubMed:26371552, PubMed:27661253).

Acts redundantly with noca-1 to control circumferential microtubule assembly along the body which is necessary for larval development, viability, morphology and integrity of the epidermis (PubMed:26371552).

Promotes microtubule stability and polymerization in neurons (PubMed:24569477).

Involved in the maintenance of neurite morphology in ALM and PLM neurons (PubMed:25437544, PubMed:24569477, PubMed:24569480).

May play a role in synaptic protein localization in the PLM neuron (PubMed:24569477).

May act upstream of dlk-1 in neuronal regeneration (PubMed:25437544, PubMed:24569480).

Plays a role in postembryonic epidermal tissue integrity and wound healing (PubMed:27661253).

5 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Patronin (microtubule-binding protein) homologImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ptrn-1Imported
ORF Names:F35B3.5Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

WormBase

More...
WormBasei
F35B3.5a ; CE48430 ; WBGene00004121 ; ptrn-1
F35B3.5c ; CE48765 ; WBGene00004121 ; ptrn-1
F35B3.5d ; CE48517 ; WBGene00004121 ; ptrn-1
F35B3.5e ; CE49594 ; WBGene00004121 ; ptrn-1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane, Microtubule

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Viable with no gross morphological defects, but exhibit uncoordinated locomotion and body positioning (PubMed:24569477, PubMed:24569480, PubMed:26371552). Small reduction in the density of microtubule bundles along the length of the body (PubMed:25437544, PubMed:26371552). Fewer microtubules in the axons of PLM and ALM neurons (PubMed:25437544, PubMed:24569477). Defective touch neuron morphology with ectopic neurites extending from the cell bodies of ALM neurons (PubMed:25437544). Irregular PLM neuron morphology including defective PLM neuron commissure extension, loss of collateral branches, presynaptic varicosities, overextended neurites and abnormal synapse localization as identified by lack of small GTPase rab-3 and snb-1 at synaptic patches (PubMed:24569477, PubMed:24569480). Impaired PLM neuron regeneration following severing of the PLM axon (PubMed:25437544). Loss of circumferential microtubule bundles and shortening of remaining bundles (PubMed:27661253). Increased microtubule growth rates (PubMed:27661253). Delayed wound closure (PubMed:27661253). Treatment with a microtubule stabilizing drug, paclitaxel, results in epidermal morphology defects (PubMed:27661253). Treatment with a microtubule destabilizing drug, colchicine, results in loss of light touch sensitivity and ectopic sprouting from neuronal axons (PubMed:24569477). Double knockout with noca-1 isoforms results in severe developmental defects with 60% not surviving beyond early postembryonic stages, mainly dying at the larval developmental stage L4, and slow growth with surviving mutants being smaller in size and uncoordinated (PubMed:26371552). Double mutants also have significantly fewer microtubule bundles along the length of the body, broken or branched seam cell syncytia that is disconnected from the head and the cuticles have increased permeability (PubMed:26371552). In a dapk-1 mutant background, suppression of the epidermal morphology defects (PubMed:27661253).5 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004361731 – 1112Patronin (microtubule-binding protein) homologCuratedAdd BLAST1112

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
U4PAZ9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in larval and adult epidermis, intestine and pharynx (PubMed:26371552). Broadly expressed in the nervous system (PubMed:24569480, PubMed:26371552). Expressed in body wall muscle cells (PubMed:24569477).3 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed throughout development (PubMed:24569477). Expressed in stretches and puncta in the body syncytium and in puncta within seam cells (PubMed:26371552).2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00004121, Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with dapk-1.

1 Publication

GO - Molecular functioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
U4PAZ9, 1 interactor

STRING: functional protein association networks

More...
STRINGi
6239.F35B3.5c

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
U4PAZ9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini165 – 286Calponin-homology (CH)PROSITE-ProRule annotationAdd BLAST122
Domaini972 – 1109CKKPROSITE-ProRule annotationAdd BLAST138

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni324 – 358DisorderedSequence analysisAdd BLAST35
Regioni485 – 504DisorderedSequence analysisAdd BLAST20
Regioni542 – 566DisorderedSequence analysisAdd BLAST25
Regioni788 – 834DisorderedSequence analysisAdd BLAST47
Regioni916 – 965DisorderedSequence analysisAdd BLAST50

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili850 – 914Sequence analysisAdd BLAST65

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi344 – 358Polar residuesSequence analysisAdd BLAST15
Compositional biasi800 – 834Basic and acidic residuesSequence analysisAdd BLAST35
Compositional biasi922 – 965Polar residuesSequence analysisAdd BLAST44

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The CKK domain binds microtubules. Might be required for microtubule stabilization (PubMed:27661253).PROSITE-ProRule annotation1 Publication
The Calponin-homology (CH) domain might negatively regulate the CKK domain.1 Publication
The coiled-coil domain contributes to microtubule binding and might negatively regulate the CKK domain.1 Publication

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CAMSAP1 family.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3654, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182975

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_274207_0_0_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
RGLYTWD

Database of Orthologous Groups

More...
OrthoDBi
162094at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.418.10, 1 hit
3.10.20.360, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032940, CAMSAP
IPR022613, CAMSAP_CH
IPR001715, CH-domain
IPR036872, CH_dom_sf
IPR038209, CKK_dom_sf
IPR014797, CKK_domain
IPR011033, PRC_barrel-like_sf

The PANTHER Classification System

More...
PANTHERi
PTHR21595, PTHR21595, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF11971, CAMSAP_CH, 1 hit
PF08683, CAMSAP_CKK, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01051, CAMSAP_CKK, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47576, SSF47576, 1 hit
SSF50346, SSF50346, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50021, CH, 1 hit
PS51508, CKK, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform cImported (identifier: U4PAZ9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDFPLPALLA IEDYDENEGK LAASIRWLIS RVYEEKRDMP DKLRDGVQRD
60 70 80 90 100
ENGHFQIDEA VVGALCNGSL YAQAAAKIFK ESALVTKGHG AVLAVLTDYG
110 120 130 140 150
IDVLHDGNEL VEEAQLVASA PFNMSAHLAI IDALMMAHLR DVIPVSRVVE
160 170 180 190 200
AVSRHTAVEP SEKPIDSVDA LLFWINKICL LVRDDVERED SNTNIPEMED
210 220 230 240 250
LYEDISDGQC LCALLHWYRP HEMPVADISF NDSATTRDCQ YNLMLLQLFC
260 270 280 290 300
RHHLAVDPFH FEIEDLLYLR DSLQMNVNAF LADLFVQFEP PVTPEPVETP
310 320 330 340 350
RIGPSPRRFV PASAIPDLRA ANAAARSSMH NRNRPRMYNP PPAVSHSQGP
360 370 380 390 400
SRSVSRMSQD SLFYSRPASI ALQRRSMDQD SVTDFQTIRQ GFENQAGTAQ
410 420 430 440 450
LNRYDGSVTA SVRLAMEEKR RKHDQQMAQM SFSSANETER LEKSKAAFFA
460 470 480 490 500
LRKNDNDQTS KGKEEWYDHF EAKLRALELR VGLEEGEDGT QSARLNRASS
510 520 530 540 550
QPSVVQAGQT YPANYMTLPM NAAAQMTQSY IQHPQTPHDY YMQQQMQQQQ
560 570 580 590 600
QQQAQAQSNY ASPSQLRNSL SNGMINHAGY IVQSMYPGDY QQQQQQMQMQ
610 620 630 640 650
QGQMPVQPVG AYTPEGYFIP HHMQPIPVQQ GYQQMPQPGM GFNGMPATSQ
660 670 680 690 700
PGFNMEGSPA QMGYIQTANK PLDMEMPMQQ QPPQQPPQQM LPPNQNAFHL
710 720 730 740 750
HSKSDDATQV QADPPLEINR NLTNWGMTYK QEMPARSIPS RRTWQNETFI
760 770 780 790 800
KNELDLVNSK ESVPHITDET TTQPEEAARR FPDLMLDNHS ENLAPGRGFS
810 820 830 840 850
RQNDRDDLST GRKSDDSPTD TPGRTFDDDE GSGENMEKIA NERRIAKKAA
860 870 880 890 900
LIAKTMKRKE EIETKVDLAE QRNAERRQVE NEKKELALRK KVEKEQQRQK
910 920 930 940 950
ILDEYKRKKL EKELGAELSA RSTGRGHSQP PFIRTKSQMS EVTESSRQNT
960 970 980 990 1000
PRMRGQSSVE QRVSVSSLAE PTHKLYAKTV TKSNRGLINN ALQFSVFPGA
1010 1020 1030 1040 1050
VNNATRQATI TQMASSSSKH FLILFRDQKC QYRGLYTWDE ISDTAVKISG
1060 1070 1080 1090 1100
QGPPKCTEAM MNSMFKYDSG AKNFTNIATK HLSATIDGFA ILDQYWQKAR
1110
IPHSGTPAHK NN
Length:1,112
Mass (Da):125,606
Last modified:December 11, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i721FB39A3BB9CBD5
GO
Isoform aImported (identifier: U4PAZ9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     431-432: Missing.

Show »
Length:1,110
Mass (Da):125,372
Checksum:iD8F8076447978780
GO
Isoform dImported (identifier: U4PAZ9-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-726: Missing.

Show »
Length:386
Mass (Da):43,856
Checksum:i40007313EB25977B
GO
Isoform eImported (identifier: U4PAZ9-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-515: Missing.

Show »
Length:597
Mass (Da):67,698
Checksum:iD35DE1230772CD45
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0582711 – 726Missing in isoform d. CuratedAdd BLAST726
Alternative sequenceiVSP_0582721 – 515Missing in isoform e. CuratedAdd BLAST515
Alternative sequenceiVSP_058273431 – 432Missing in isoform a. Curated2

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284606 Genomic DNA Translation: CDH92934.1
BX284606 Genomic DNA Translation: CCD66253.2
BX284606 Genomic DNA Translation: CDH92935.1
BX284606 Genomic DNA Translation: CDM63458.1

NCBI Reference Sequences

More...
RefSeqi
NP_001294829.1, NM_001307900.1 [U4PAZ9-4]
NP_001294846.1, NM_001307917.1 [U4PAZ9-1]
NP_001294847.1, NM_001307918.1 [U4PAZ9-3]
NP_510751.4, NM_078350.6 [U4PAZ9-2]

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
F35B3.5a.1; F35B3.5a.1; WBGene00004121 [U4PAZ9-2]
F35B3.5c.1; F35B3.5c.1; WBGene00004121 [U4PAZ9-1]
F35B3.5d.1; F35B3.5d.1; WBGene00004121 [U4PAZ9-3]
F35B3.5e.1; F35B3.5e.1; WBGene00004121 [U4PAZ9-4]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
181743

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_F35B3.5

UCSC genome browser

More...
UCSCi
F35B3.5a, c. elegans

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA Translation: CDH92934.1
BX284606 Genomic DNA Translation: CCD66253.2
BX284606 Genomic DNA Translation: CDH92935.1
BX284606 Genomic DNA Translation: CDM63458.1
RefSeqiNP_001294829.1, NM_001307900.1 [U4PAZ9-4]
NP_001294846.1, NM_001307917.1 [U4PAZ9-1]
NP_001294847.1, NM_001307918.1 [U4PAZ9-3]
NP_510751.4, NM_078350.6 [U4PAZ9-2]

3D structure databases

SMRiU4PAZ9
ModBaseiSearch...

Protein-protein interaction databases

IntActiU4PAZ9, 1 interactor
STRINGi6239.F35B3.5c

Proteomic databases

PaxDbiU4PAZ9

Genome annotation databases

EnsemblMetazoaiF35B3.5a.1; F35B3.5a.1; WBGene00004121 [U4PAZ9-2]
F35B3.5c.1; F35B3.5c.1; WBGene00004121 [U4PAZ9-1]
F35B3.5d.1; F35B3.5d.1; WBGene00004121 [U4PAZ9-3]
F35B3.5e.1; F35B3.5e.1; WBGene00004121 [U4PAZ9-4]
GeneIDi181743
KEGGicel:CELE_F35B3.5
UCSCiF35B3.5a, c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
181743
WormBaseiF35B3.5a ; CE48430 ; WBGene00004121 ; ptrn-1
F35B3.5c ; CE48765 ; WBGene00004121 ; ptrn-1
F35B3.5d ; CE48517 ; WBGene00004121 ; ptrn-1
F35B3.5e ; CE49594 ; WBGene00004121 ; ptrn-1

Phylogenomic databases

eggNOGiKOG3654, Eukaryota
GeneTreeiENSGT00950000182975
HOGENOMiCLU_274207_0_0_1
OMAiRGLYTWD
OrthoDBi162094at2759

Miscellaneous databases

Protein Ontology

More...
PROi
PR:U4PAZ9

Gene expression databases

BgeeiWBGene00004121, Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues

Family and domain databases

Gene3Di1.10.418.10, 1 hit
3.10.20.360, 1 hit
InterProiView protein in InterPro
IPR032940, CAMSAP
IPR022613, CAMSAP_CH
IPR001715, CH-domain
IPR036872, CH_dom_sf
IPR038209, CKK_dom_sf
IPR014797, CKK_domain
IPR011033, PRC_barrel-like_sf
PANTHERiPTHR21595, PTHR21595, 2 hits
PfamiView protein in Pfam
PF11971, CAMSAP_CH, 1 hit
PF08683, CAMSAP_CKK, 1 hit
SMARTiView protein in SMART
SM01051, CAMSAP_CKK, 1 hit
SUPFAMiSSF47576, SSF47576, 1 hit
SSF50346, SSF50346, 1 hit
PROSITEiView protein in PROSITE
PS50021, CH, 1 hit
PS51508, CKK, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPTRN1_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: U4PAZ9
Secondary accession number(s): Q966J8, U4PLF6, W6SB68
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 11, 2016
Last sequence update: December 11, 2013
Last modified: September 29, 2021
This is version 56 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again