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Entry version 47 (17 Jun 2020)
Sequence version 1 (11 Dec 2013)
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Protein
Submitted name:

FI24217p1

Gene

psidin-RA

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
FI24217p1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:psidin-RAImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
U3Q053

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0243511 Expressed in embryonic/larval hemocyte (Drosophila) and 29 other tissues

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
U3Q053 baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini23 – 147TPR_REGIONInterPro annotationAdd BLAST125

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni841 – 862DisorderedSequence analysisAdd BLAST22

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili657 – 677Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi841 – 860PolyampholyteSequence analysisAdd BLAST20

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2053 Eukaryota
ENOG410XRXD LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183174

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_008075_0_0_1

KEGG Orthology (KO)

More...
KOi
K17973

Identification of Orthologs from Complete Genome Data

More...
OMAi
ICRRMWA

Database of Orthologous Groups

More...
OrthoDBi
1022953at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
U3Q053

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019183 N-acetylTrfase_B_cplx_non-cat
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf

The PANTHER Classification System

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PANTHERi
PTHR22767:SF3 PTHR22767:SF3, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF09797 NatB_MDM20, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48452 SSF48452, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50293 TPR_REGION, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

U3Q053-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAQQQGMDSA LFERRLRPVY DNLEVGNNRK ALQESEKLLR KHPNLLCARA
60 70 80 90 100
LKGLSLLRLG RYDESHGCLQ TVAEEKPTDD STLQVLSFCY REMEQLDKIV
110 120 130 140 150
ELYQHAVKQN PGNEELLAHL FISHVRVEDY KAQQAVALQL YKAQPKNAYY
160 170 180 190 200
FWSVISVVFQ GIRGPESALP EKRKIYLGLA QRMVDKHIKE GKMETEQEAF
210 220 230 240 250
LYLHILKLQN KYQEAWEFLT GELCAKLYPG APVSMKFELL KELGNWRELN
260 270 280 290 300
ELLQQLLDAD RDRWDFYKEY IQSSFELLKL TPQGVENGDK DSLARCQEFL
310 320 330 340 350
QRIIDSSERK KRGPYLARLE LHQRMRAEQL PAEKLIGDFD EMVIEYFRLF
360 370 380 390 400
GDKSCCTHDI ALFLPSISMN QRQALASKLL LESGVTSTSL PKNKEQLQKH
410 420 430 440 450
LCALQISRMC GSHMDLPADH LLAFYTALKL HYEHGRTTFG KKLLATEMGP
460 470 480 490 500
SDAYALLAAN VMYDLSRREN KSDHLFEALC LLQYVLRNST SNFHVKLLSL
510 520 530 540 550
KIYHLFGCQV GAQEMYEYLD IKQIQLDSMG YVHCQLLALG GRFSGNRNVY
560 570 580 590 600
DATLKFFTNS YKERLEYIAL TYRFCTFSKM EEFMNFKERL TNSLQYVACS
610 620 630 640 650
VEAQICDLVS CYGNITQNLS AYVAMSIEPA EDRIAWHELS DNRDLGAIIR
660 670 680 690 700
WDPLHEVDAA EERRESFDQE VEVLQVRSLM LRLFASFIDL YHGAGLKDSP
710 720 730 740 750
AGAETATLEL LRESWTGLFQ RLRVMNYKPL AQKFLVNLLP TRLHLLLDMP
760 770 780 790 800
YERFFDDLAQ LVLDLQSGSA KLAEQCKRVG DNVIATMELC VQTINESNES
810 820 830 840 850
NGIDGLWKRR GQQQKVAASL EMLSLYAFLL SVLNDKLQVS SKTKTKKKPV
860 870 880 890 900
ENKVDGPQPI SEKERSQMLQ ELMRQLKHKF EACDTAIRSW KAPVLPRDLS
910 920 930 940
SFMSDMSLKP EVEATLIGDV SATFKDSHEL MVTELRNLLK DKIRMVAK
Length:948
Mass (Da):109,110
Last modified:December 11, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i799238B481ED80ED
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BT150356 mRNA Translation: AGW52165.1

NCBI Reference Sequences

More...
RefSeqi
NP_650858.1, NM_142601.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0083829; FBpp0083238; FBgn0243511

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
42389

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG4845

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT150356 mRNA Translation: AGW52165.1
RefSeqiNP_650858.1, NM_142601.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

PRIDEiU3Q053

Genome annotation databases

EnsemblMetazoaiFBtr0083829; FBpp0083238; FBgn0243511
GeneIDi42389
KEGGidme:Dmel_CG4845

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
42389

Phylogenomic databases

eggNOGiKOG2053 Eukaryota
ENOG410XRXD LUCA
GeneTreeiENSGT00950000183174
HOGENOMiCLU_008075_0_0_1
KOiK17973
OMAiICRRMWA
OrthoDBi1022953at2759
PhylomeDBiU3Q053

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
42389 0 hits in 1 CRISPR screen

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
42389

Gene expression databases

BgeeiFBgn0243511 Expressed in embryonic/larval hemocyte (Drosophila) and 29 other tissues
ExpressionAtlasiU3Q053 baseline and differential

Family and domain databases

Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR019183 N-acetylTrfase_B_cplx_non-cat
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
PANTHERiPTHR22767:SF3 PTHR22767:SF3, 1 hit
PfamiView protein in Pfam
PF09797 NatB_MDM20, 1 hit
SUPFAMiSSF48452 SSF48452, 1 hit
PROSITEiView protein in PROSITE
PS50293 TPR_REGION, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiU3Q053_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: U3Q053
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 11, 2013
Last sequence update: December 11, 2013
Last modified: June 17, 2020
This is version 47 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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