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Protein
Submitted name:

Hepatocyte nuclear factor 6

Gene

ONECUT1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Hepatocyte nuclear factor 6Imported
Gene namesi
Name:ONECUT1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

EuPathDBiHostDB:ENSG00000169856.8
HGNCiHGNC:8138 ONECUT1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000169856

PTM / Processingi

Proteomic databases

PeptideAtlasiU3KQR8

Expressioni

Gene expression databases

BgeeiENSG00000169856 Expressed in 39 organ(s), highest expression level in body of pancreas
ExpressionAtlasiU3KQR8 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliU3KQR8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini88 – 174CUTInterPro annotationAdd BLAST87

Phylogenomic databases

GeneTreeiENSGT00530000063019

Family and domain databases

InterProiView protein in InterPro
IPR003350 CUT_dom
IPR010982 Lambda_DNA-bd_dom_sf
PfamiView protein in Pfam
PF02376 CUT, 1 hit
SMARTiView protein in SMART
SM01109 CUT, 1 hit
SUPFAMiSSF47413 SSF47413, 1 hit
PROSITEiView protein in PROSITE
PS51042 CUT, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

U3KQR8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XLYTPYHKDV AGMGQSLSPL SSSGLGSIHN SQQGLPHYAH PGAAMPTDKM
60 70 80 90 100
LTPNGFEAHH PAMLGRHGEQ HLTPTSAGMV PINGLPPHHP HAHLNAQGHG
110 120 130 140 150
QLLGTAREPN PSVTGAQAIF AQRVLCRSQG TLSDLLRNPK PWSKLKSGRE
160 170 180
TFRRMWKWLQ EPEFQRMSAL RLAGTAREAR TA
Length:182
Mass (Da):19,845
Last modified:November 13, 2013 - v1
Checksum:i29515E5DCA60A457
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9UBC0HNF6_HUMAN
Hepatocyte nuclear factor 6
ONECUT1 HNF6, HNF6A
465Annotation score:
H0YMS2H0YMS2_HUMAN
Hepatocyte nuclear factor 6
ONECUT1
66Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC016044 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000570208; ENSP00000476168; ENSG00000169856
UCSCiuc059jke.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC016044 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliU3KQR8
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiU3KQR8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000570208; ENSP00000476168; ENSG00000169856
UCSCiuc059jke.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000169856.8
HGNCiHGNC:8138 ONECUT1
OpenTargetsiENSG00000169856
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00530000063019

Miscellaneous databases

ChiTaRSiONECUT1 human

Gene expression databases

BgeeiENSG00000169856 Expressed in 39 organ(s), highest expression level in body of pancreas
ExpressionAtlasiU3KQR8 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR003350 CUT_dom
IPR010982 Lambda_DNA-bd_dom_sf
PfamiView protein in Pfam
PF02376 CUT, 1 hit
SMARTiView protein in SMART
SM01109 CUT, 1 hit
SUPFAMiSSF47413 SSF47413, 1 hit
PROSITEiView protein in PROSITE
PS51042 CUT, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiU3KQR8_HUMAN
AccessioniPrimary (citable) accession number: U3KQR8
Entry historyiIntegrated into UniProtKB/TrEMBL: November 13, 2013
Last sequence update: November 13, 2013
Last modified: September 12, 2018
This is version 24 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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