UniProtKB - U3KQL2 (U3KQL2_HUMAN)
Protein
Acylphosphatase
Gene
ACYP2
Organism
Homo sapiens (Human)
Status
Functioni
Catalytic activityi
- EC:3.6.1.7PROSITE-ProRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 97 | PROSITE-ProRule annotation | 1 | |
Active sitei | 115 | PROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- acylphosphatase activity Source: UniProtKB-EC
Keywordsi
Molecular function | HydrolasePROSITE-ProRule annotation |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:ACYP2Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:180, ACYP2 |
VEuPathDBi | HostDB:ENSG00000170634.12 |
Expressioni
Gene expression databases
Bgeei | ENSG00000170634, Expressed in quadriceps femoris and 235 other tissues |
ExpressionAtlasi | U3KQL2, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 82 – 172 | Acylphosphatase-likeInterPro annotationAdd BLAST | 91 |
Sequence similaritiesi
Belongs to the acylphosphatase family.UniRule annotation
Phylogenomic databases
GeneTreei | ENSGT00390000011103 |
HOGENOMi | CLU_1554750_0_0_1 |
OrthoDBi | 1502266at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR020456, Acylphosphatase IPR001792, Acylphosphatase-like_dom IPR036046, Acylphosphatase-like_dom_sf IPR017968, Acylphosphatase_CS |
PANTHERi | PTHR10029, PTHR10029, 1 hit |
Pfami | View protein in Pfam PF00708, Acylphosphatase, 1 hit |
PRINTSi | PR00112, ACYLPHPHTASE |
SUPFAMi | SSF54975, SSF54975, 1 hit |
PROSITEi | View protein in PROSITE PS00151, ACYLPHOSPHATASE_2, 1 hit PS51160, ACYLPHOSPHATASE_3, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All
U3KQL2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLLTQSLFGG LFPRTRETMR RYKVSLFYLG CSRTPNVKLS SCLGLPCCWD
60 70 80 90 100
YSYKFIQLSE FGFGQVIIVS EEPWKENISC SSTTFIKSTI CLSVCFRMYT
110 120 130 140 150
EDEARKIGVV GWVKNTSKGT VTGQVQGPED KVNSMKSWLS KVGSPSSRID
160 170
RTNFSNEKTI SKLEYSNFSI RY
Computationally mapped potential isoform sequencesi
There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP14621 | ACYP2_HUMAN | Acylphosphatase-2 | ACYP2 ACYP | 99 | Annotation score: | ||
F8WA34 | F8WA34_HUMAN | Acylphosphatase | ACYP2 | 98 | Annotation score: | ||
E9PF46 | E9PF46_HUMAN | Acylphosphatase | ACYP2 | 97 | Annotation score: | ||
U3KPX1 | U3KPX1_HUMAN | Acylphosphatase | ACYP2 | 66 | Annotation score: | ||
U3KPX8 | U3KPX8_HUMAN | Acylphosphatase-2 | ACYP2 | 83 | Annotation score: | ||
U3KQ09 | U3KQ09_HUMAN | Acylphosphatase-2 | ACYP2 | 40 | Annotation score: | ||
U3KQ94 | U3KQ94_HUMAN | Acylphosphatase-2 | ACYP2 hCG_2040114 | 116 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC008068 Genomic DNA No translation available. AC008280 Genomic DNA No translation available. AC073879 Genomic DNA No translation available. AC092622 Genomic DNA No translation available. AC108929 Genomic DNA No translation available. |
RefSeqi | NP_001307515.1, NM_001320586.1 |
Genome annotation databases
Ensembli | ENST00000607452; ENSP00000475986; ENSG00000170634 |
GeneIDi | 98 |
UCSCi | uc061jdu.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC008068 Genomic DNA No translation available. AC008280 Genomic DNA No translation available. AC073879 Genomic DNA No translation available. AC092622 Genomic DNA No translation available. AC108929 Genomic DNA No translation available. |
RefSeqi | NP_001307515.1, NM_001320586.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | U3KQL2 |
PRIDEi | U3KQL2 |
Protocols and materials databases
Antibodypediai | 30250, 105 antibodies |
DNASUi | 98 |
Genome annotation databases
Ensembli | ENST00000607452; ENSP00000475986; ENSG00000170634 |
GeneIDi | 98 |
UCSCi | uc061jdu.1, human |
Organism-specific databases
CTDi | 98 |
HGNCi | HGNC:180, ACYP2 |
OpenTargetsi | ENSG00000170634 |
VEuPathDBi | HostDB:ENSG00000170634.12 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000011103 |
HOGENOMi | CLU_1554750_0_0_1 |
OrthoDBi | 1502266at2759 |
Miscellaneous databases
BioGRID-ORCSi | 98, 6 hits in 993 CRISPR screens |
ChiTaRSi | ACYP2, human |
GenomeRNAii | 98 |
Gene expression databases
Bgeei | ENSG00000170634, Expressed in quadriceps femoris and 235 other tissues |
ExpressionAtlasi | U3KQL2, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR020456, Acylphosphatase IPR001792, Acylphosphatase-like_dom IPR036046, Acylphosphatase-like_dom_sf IPR017968, Acylphosphatase_CS |
PANTHERi | PTHR10029, PTHR10029, 1 hit |
Pfami | View protein in Pfam PF00708, Acylphosphatase, 1 hit |
PRINTSi | PR00112, ACYLPHPHTASE |
SUPFAMi | SSF54975, SSF54975, 1 hit |
PROSITEi | View protein in PROSITE PS00151, ACYLPHOSPHATASE_2, 1 hit PS51160, ACYLPHOSPHATASE_3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | U3KQL2_HUMAN | |
Accessioni | U3KQL2Primary (citable) accession number: U3KQL2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 13, 2013 |
Last sequence update: | November 13, 2013 | |
Last modified: | April 7, 2021 | |
This is version 52 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |