UniProtKB - U3KQ31 (U3KQ31_HUMAN)
Protein
Submitted name:
T-box transcription factor TBX18
Gene
TBX18
Organism
Homo sapiens (Human)
Status
Functioni
Caution
Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
GO - Molecular functioni
- DNA binding Source: UniProtKB-UniRule
- DNA-binding transcription factor activity Source: InterPro
Keywordsi
Molecular function | DNA-bindingPROSITE-ProRule annotationARBA annotation |
Biological process | Transcription, Transcription regulationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: T-box transcription factor TBX18Imported |
Gene namesi | Name:TBX18Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:11595, TBX18 |
VEuPathDBi | HostDB:ENSG00000112837.16 |
Subcellular locationi
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationARBA annotationExpressioni
Gene expression databases
Bgeei | ENSG00000112837, Expressed in popliteal artery and 124 other tissues |
ExpressionAtlasi | U3KQ31, baseline and differential |
Family & Domainsi
Phylogenomic databases
GeneTreei | ENSGT00940000155566 |
HOGENOMi | CLU_014430_3_1_1 |
Family and domain databases
CDDi | cd00182, TBOX, 1 hit |
Gene3Di | 2.60.40.820, 1 hit |
InterProi | View protein in InterPro IPR008967, p53-like_TF_DNA-bd IPR036960, T-box_sf IPR001699, TF_T-box IPR018186, TF_T-box_CS |
PANTHERi | PTHR11267, PTHR11267, 1 hit |
Pfami | View protein in Pfam PF00907, T-box, 1 hit |
PRINTSi | PR00937, TBOX |
SMARTi | View protein in SMART SM00425, TBOX, 1 hit |
SUPFAMi | SSF49417, SSF49417, 1 hit |
PROSITEi | View protein in PROSITE PS01264, TBOX_2, 1 hit PS50252, TBOX_3, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
U3KQ31-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIITKAGRRM FPAMRVKISG LDPHQQYYIA MDIVPVDNKR YRYVYHSSKW
60 70 80 90 100
MVAGNADSPV PPRVYIHPDS PASGETWMRQ VISFDKLKLT NNELDDQGHI
110 120 130 140 150
ILHSMHKYQP RVHVIRKDCG DDLSPIKPVP SGEGVKAFSF PETVFTTVTA
160 170
YQNQQITRLK IDRNPFAKGF RDSGRN
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketO95935 | TBX18_HUMAN | T-box transcription factor TBX18 | TBX18 | 607 | Annotation score: | ||
U3KQH2 | U3KQH2_HUMAN | T-box transcription factor TBX18 | TBX18 | 232 | Annotation score: | ||
U3KQQ9 | U3KQQ9_HUMAN | T-box transcription factor TBX18 | TBX18 | 32 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 176 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL035694 Genomic DNA No translation available. AL590143 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000606325; ENSP00000475498; ENSG00000112837 |
UCSCi | uc063pwn.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL035694 Genomic DNA No translation available. AL590143 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | U3KQ31 |
Protocols and materials databases
Antibodypediai | 18548, 253 antibodies |
Genome annotation databases
Ensembli | ENST00000606325; ENSP00000475498; ENSG00000112837 |
UCSCi | uc063pwn.1, human |
Organism-specific databases
HGNCi | HGNC:11595, TBX18 |
OpenTargetsi | ENSG00000112837 |
VEuPathDBi | HostDB:ENSG00000112837.16 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000155566 |
HOGENOMi | CLU_014430_3_1_1 |
Miscellaneous databases
ChiTaRSi | TBX18, human |
Gene expression databases
Bgeei | ENSG00000112837, Expressed in popliteal artery and 124 other tissues |
ExpressionAtlasi | U3KQ31, baseline and differential |
Family and domain databases
CDDi | cd00182, TBOX, 1 hit |
Gene3Di | 2.60.40.820, 1 hit |
InterProi | View protein in InterPro IPR008967, p53-like_TF_DNA-bd IPR036960, T-box_sf IPR001699, TF_T-box IPR018186, TF_T-box_CS |
PANTHERi | PTHR11267, PTHR11267, 1 hit |
Pfami | View protein in Pfam PF00907, T-box, 1 hit |
PRINTSi | PR00937, TBOX |
SMARTi | View protein in SMART SM00425, TBOX, 1 hit |
SUPFAMi | SSF49417, SSF49417, 1 hit |
PROSITEi | View protein in PROSITE PS01264, TBOX_2, 1 hit PS50252, TBOX_3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | U3KQ31_HUMAN | |
Accessioni | U3KQ31Primary (citable) accession number: U3KQ31 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 13, 2013 |
Last sequence update: | November 13, 2013 | |
Last modified: | February 10, 2021 | |
This is version 43 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |