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UniProtKB - U3JAV8 (U3JAV8_DANRE)

Entry version 58 (25 May 2022)
Sequence version 1 (13 Nov 2013)
Previous versions | rss
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Protein

CAD protein

Gene

cad

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Zn2+ARBA annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: UMP biosynthesis via de novo pathway

This protein is involved in step 1, 2 and 3 of the subpathway that synthesizes (S)-dihydroorotate from bicarbonate.ARBA annotation This subpathway is part of the pathway UMP biosynthesis via de novo pathway, which is itself part of Pyrimidine metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes (S)-dihydroorotate from bicarbonate, the pathway UMP biosynthesis via de novo pathway and in Pyrimidine metabolism.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAllosteric enzymeARBA annotation, HydrolaseARBA annotation, LigaseARBA annotation, Multifunctional enzymeARBA annotation, TransferaseARBA annotation
Biological processPyrimidine biosynthesisARBA annotation
LigandATP-bindingPROSITE-ProRule annotationARBA annotation, Metal-bindingARBA annotation, Nucleotide-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-DRE-500753, Pyrimidine biosynthesis

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...UniPathwayi		UPA00070;UER00115
UPA00070;UER00116
UPA00070;UER00117

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
CAD proteinARBA annotation (EC:2.1.3.2ARBA annotation, EC:3.5.2.3ARBA annotation, EC:6.3.5.5ARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:cadImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

Organism-specific databases

Zebrafish Information Network genome database

More...ZFINi		ZDB-GENE-021030-4, cad

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSDARG00000041895, Expressed in paraxial mesoderm and 48 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		U3JAV8, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		7955.ENSDARP00000127377

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		U3JAV8

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		U3JAV8

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini521 – 713ATP-graspInterPro annotationAdd BLAST193
Domaini1057 – 1248ATP-graspInterPro annotationAdd BLAST192
Domaini1313 – 1468MGS-likeInterPro annotationAdd BLAST156

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1843 – 1877DisorderedSequence analysisAdd BLAST35

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.ARBA annotation

Keywords - Domaini

RepeatARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0370, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000157241

Family and domain databases

Conserved Domains Database

More...CDDi		cd01744, GATase1_CPSase, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.1030.10, 1 hit
3.30.1490.20, 1 hit
3.40.50.1370, 2 hits
3.40.50.1380, 1 hit
3.40.50.880, 1 hit
3.50.30.20, 1 hit

HAMAP database of protein families

More...HAMAPi		MF_00001, Asp_carb_tr, 1 hit
MF_01209, CPSase_S_chain, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR006680, Amidohydro-rel
IPR006132, Asp/Orn_carbamoyltranf_P-bd
IPR006130, Asp/Orn_carbamoylTrfase
IPR036901, Asp/Orn_carbamoylTrfase_sf
IPR002082, Asp_carbamoyltransf
IPR006131, Asp_carbamoyltransf_Asp/Orn-bd
IPR011761, ATP-grasp
IPR013815, ATP_grasp_subdomain_1
IPR006275, CarbamoylP_synth_lsu
IPR005480, CarbamoylP_synth_lsu_oligo
IPR036897, CarbamoylP_synth_lsu_oligo_sf
IPR006274, CarbamoylP_synth_ssu
IPR002474, CarbamoylP_synth_ssu_N
IPR036480, CarbP_synth_ssu_N_sf
IPR005479, CbamoylP_synth_lsu-like_ATP-bd
IPR005483, CbamoylP_synth_lsu_CPSase_dom
IPR029062, Class_I_gatase-like
IPR035686, CPSase_GATase1
IPR002195, Dihydroorotase_CS
IPR017926, GATASE
IPR011059, Metal-dep_hydrolase_composite
IPR032466, Metal_Hydrolase
IPR011607, MGS-like_dom
IPR036914, MGS-like_dom_sf
IPR016185, PreATP-grasp_dom_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01979, Amidohydro_1, 1 hit
PF02786, CPSase_L_D2, 2 hits
PF02787, CPSase_L_D3, 1 hit
PF00988, CPSase_sm_chain, 1 hit
PF00117, GATase, 1 hit
PF02142, MGS, 1 hit
PF00185, OTCace, 1 hit
PF02729, OTCace_N, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00100, AOTCASE
PR00098, CPSASE

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM01096, CPSase_L_D3, 1 hit
SM01097, CPSase_sm_chain, 1 hit
SM00851, MGS, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48108, SSF48108, 1 hit
SSF51338, SSF51338, 1 hit
SSF51556, SSF51556, 1 hit
SSF52021, SSF52021, 1 hit
SSF52317, SSF52317, 1 hit
SSF52335, SSF52335, 1 hit
SSF52440, SSF52440, 2 hits
SSF53671, SSF53671, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00670, asp_carb_tr, 1 hit
TIGR01369, CPSaseII_lrg, 1 hit
TIGR01368, CPSaseIIsmall, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50975, ATP_GRASP, 2 hits
PS00097, CARBAMOYLTRANSFERASE, 1 hit
PS00866, CPSASE_1, 2 hits
PS00867, CPSASE_2, 2 hits
PS00482, DIHYDROOROTASE_1, 1 hit
PS00483, DIHYDROOROTASE_2, 1 hit
PS51855, MGS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

U3JAV8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLKMASLVL EDGTTFKGRL FGAVSSVSGE VVFQTGMVGY PEALTDPSYK 
        60         70         80         90        100
SQILTLTYPM IGNYGIPKDE DGEFGLSKWF ESSQIHAAAL IVGEVSENPS 
       110        120        130        140        150
HWSAAKSLDE WLREQGIPGL QGVDTRCLTK KIREKGTMLG KLVVEGTPAD 
       160        170        180        190        200
NIPFDNPDAR NLVKEVSMKA PKVFNPEGTV RITAIDCGIK YNQIRCLCQR 
       210        220        230        240        250
GARVTVVPWD QPLDSNDFDG LFISNGPGNP EYCKETVENI RKVACVENPK 
       260        270        280        290        300
PIFGICLGHQ LLSLVIGAKT YKMKYGNRGH NQPCIHKGTS RCYITSQNHG 
       310        320        330        340        350
FAVDPETLPK DWDVLFTNAN DQTSEGIVHN HKPLFSVQFH PEHMAGPTDL 
       360        370        380        390        400
VGLFDVFLDT VRDVKENKAG KSVKQRLMEH LTFPGSPDPN AFVRPRKVLV 
       410        420        430        440        450
LGSGGLSIGQ AGEFDYSGSQ AIKAMKEENI QTILINPNIA TVQTSKGLAD 
       460        470        480        490        500
KVYFLPITPE YVTQVIKNER PDGVLLTFGG QTALNCGVEL KKQGVLEKYK 
       510        520        530        540        550
VRVLGTPVAS IEMTEDRKIF VEKMEEINEH VAPSEAAMSV EQAVAAAERL 
       560        570        580        590        600
GYPVLVRSAF ALGGLGSGFA NNRDEMITLV TQAFAHTSQV LVDKSLKGWK 
       610        620        630        640        650
EIEYEVVRDA YDNCVTVCNM ENIDPLGIHT GESIVVAPSQ TLNDYEYNML 
       660        670        680        690        700
RNTAIKVIRH LGVVGECNIQ YALNPESEQY YIIEVNARLS RSSALASKAT 
       710        720        730        740        750
GYPLAYVAAK LSLGIPLPVL KNSVTNSTTA NFEPSLDYCV VKVPRWDLSK 
       760        770        780        790        800
FLRVSTKIGS SMKSVGEVMA IGRSFEEAFQ KALRMVDENC VGFDHTIKPE 
       810        820        830        840        850
SEEELQTPTD KRIFVLAAAL HAGYTVERLY ELTKIDHWFL HKMKNIADHK 
       860        870        880        890        900
KLLETYKQDE SAMPPEIMRK AKQLGFSDKQ IAQAVQSTEL AVRKLRRDWK 
       910        920        930        940        950
IFPVVKQIDT VAAEWPAQTN YLYLTYHGSE SDVVFEQPHV MVIGSGVYRI 
       960        970        980        990       1000
GSSVEFDWCA VGCIMELRKM GYKTIMVNYN PETVSTDYDM CDRLYFDEIS 
      1010       1020       1030       1040       1050
FEVVMDIYEM ENPEGVILSM GGQLPNNIAM SLHRQQCRIL GTSPEFIDNA 
      1060       1070       1080       1090       1100
ENRFKFSRML DTIGISQPRW KELSDTESAV NFCETVGYPC LVRPSYVLSG 
      1110       1120       1130       1140       1150
AAMNVAYSDT DMEKFLSSAV AVSKEHPVVI SKFIQEAKEI DVDAVACDGE 
      1160       1170       1180       1190       1200
VIAIAVSEHV ENAGVHSGDA TLVTPPQDIN QKTMERIKMI VHAIGQELQV 
      1210       1220       1230       1240       1250
TGPFNLQLIA KDDQLKVIEC NVRVSRSFPY VSKTLGVDLV ALATRVILGE 
      1260       1270       1280       1290       1300
EVEAVGLMRG NGIVGVKVPQ FSFSRLAGAD VVLGVEMTST GEVACFGENR 
      1310       1320       1330       1340       1350
YEAYLKAMLS TGFKIPKKNI LLSIGSYKNK SELLPTVQTL ESLGYNLYAS 
      1360       1370       1380       1390       1400
LGTADFYTEH GVKVMAVDWP FEEESDCPNK DKQRNIMDYL EENHFDLVIN 
      1410       1420       1430       1440       1450
LSMRNSGGRR LSSFVTKGYR TRRMAIDFSV PLITDIKCTK LFVQALKQIG 
      1460       1470       1480       1490       1500
QAPRVKTHVD SMTSQKLIRL PGLIDVHVHL REPGATHKED FSSGTAAALA 
      1510       1520       1530       1540       1550
GGITMVCAMP NTNPAIIDPN SFTMAQKLAK AGCRCDYALF VGASSDNAAL 
      1560       1570       1580       1590       1600
LPSIASSTAG LKMYLNDTYS TLKMDNVSLW MEHFEKWPKH LPIVAHAEKQ 
      1610       1620       1630       1640       1650
TVAAILLVAQ LYQRPVHICH VAKKEEILII RAAKQKGIQV TCEVAPHHLF 
      1660       1670       1680       1690       1700
LCEDNVPVIG KDKAQVRPML GTREDMEALW ENLDIIDCFA TDHAPHSAEE 
      1710       1720       1730       1740       1750
KISEKPPPGY PGLETMLPLL FTAVSEGRLT VDDIIKRLYE NPRKIFSLPA 
      1760       1770       1780       1790       1800
QEDTYVEVDL EQEWIIPKHM QFTKSKWTPF EGMKVKGKVM RVVLRGEVAY 
      1810       1820       1830       1840       1850
IDGQVLVPPG YGQDVKSWSA TPTATTEVIM DAPKRVIEAM TPERPRQAAP 
      1860       1870       1880       1890       1900
VDVVRSRAPS PRRSAGDGRF ILPPRIHRSS DPGLPPELAL PAEAYAHPPP 
      1910       1920       1930       1940       1950
LARILSPQAG QPQILPHPQT SPLLHPLVGQ HILSVRQFSK EQMSHLFNVA 
      1960       1970       1980       1990       2000
HTLRLMVQKE RPLDILKGKV MASMFYEVST RTSSSFAAAM HRLGGSVVHF 
      2010       2020       2030       2040       2050
CESTSSTQKG ESLVDSVNTM SCYADVIVLR HPIPGAVESA ARHCRRPVIN 
      2060       2070       2080       2090       2100
AGDGVGEHPT QALLDIFTIR EELGTVNGMT ITMVGDLKHG RTVHSLARLL 
      2110       2120       2130       2140       2150
TQYRITLRYV APKNLSMPAE IIDFVASKGI KQEEFNSIEE ALPDTDVLYM 
      2160       2170       2180       2190       2200
TRIQKERFSS EKEYNACFGQ FILTPHIMTG AKRKMVVMHP LPRVNEISVE 
      2210       2220       2230
VDTDPRAAYF RQAENGMYIR MALLATVLGR
Length:2,230
Mass (Da):247,303
Last modified:November 13, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5E64FDB9C9AAB5C4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F1Q9V4F1Q9V4_DANRE
Carbamoyl-phosphate synthetase 2, a...
cad
485Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
BX511178 Genomic DNA No translation available.

NCBI Reference Sequences

More...RefSeqi		NP_001295754.1, NM_001308825.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSDART00000153310.3; ENSDARP00000127377.1; ENSDARG00000041895.10

Database of genes from NCBI RefSeq genomes

More...GeneIDi		266992

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		dre:266992

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX511178 Genomic DNA No translation available.
RefSeqiNP_001295754.1, NM_001308825.1

3D structure databases

AlphaFoldDBiU3JAV8
SMRiU3JAV8
ModBaseiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000127377

Genome annotation databases

EnsembliENSDART00000153310.3; ENSDARP00000127377.1; ENSDARG00000041895.10
GeneIDi266992
KEGGidre:266992

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		790
ZFINiZDB-GENE-021030-4, cad

Phylogenomic databases

eggNOGiKOG0370, Eukaryota
GeneTreeiENSGT00940000157241

Enzyme and pathway databases

UniPathwayiUPA00070;UER00115
UPA00070;UER00116
UPA00070;UER00117
ReactomeiR-DRE-500753, Pyrimidine biosynthesis

Gene expression databases

BgeeiENSDARG00000041895, Expressed in paraxial mesoderm and 48 other tissues
ExpressionAtlasiU3JAV8, baseline and differential

Family and domain databases

CDDicd01744, GATase1_CPSase, 1 hit
Gene3Di1.10.1030.10, 1 hit
3.30.1490.20, 1 hit
3.40.50.1370, 2 hits
3.40.50.1380, 1 hit
3.40.50.880, 1 hit
3.50.30.20, 1 hit
HAMAPiMF_00001, Asp_carb_tr, 1 hit
MF_01209, CPSase_S_chain, 1 hit
InterProiView protein in InterPro
IPR006680, Amidohydro-rel
IPR006132, Asp/Orn_carbamoyltranf_P-bd
IPR006130, Asp/Orn_carbamoylTrfase
IPR036901, Asp/Orn_carbamoylTrfase_sf
IPR002082, Asp_carbamoyltransf
IPR006131, Asp_carbamoyltransf_Asp/Orn-bd
IPR011761, ATP-grasp
IPR013815, ATP_grasp_subdomain_1
IPR006275, CarbamoylP_synth_lsu
IPR005480, CarbamoylP_synth_lsu_oligo
IPR036897, CarbamoylP_synth_lsu_oligo_sf
IPR006274, CarbamoylP_synth_ssu
IPR002474, CarbamoylP_synth_ssu_N
IPR036480, CarbP_synth_ssu_N_sf
IPR005479, CbamoylP_synth_lsu-like_ATP-bd
IPR005483, CbamoylP_synth_lsu_CPSase_dom
IPR029062, Class_I_gatase-like
IPR035686, CPSase_GATase1
IPR002195, Dihydroorotase_CS
IPR017926, GATASE
IPR011059, Metal-dep_hydrolase_composite
IPR032466, Metal_Hydrolase
IPR011607, MGS-like_dom
IPR036914, MGS-like_dom_sf
IPR016185, PreATP-grasp_dom_sf
PfamiView protein in Pfam
PF01979, Amidohydro_1, 1 hit
PF02786, CPSase_L_D2, 2 hits
PF02787, CPSase_L_D3, 1 hit
PF00988, CPSase_sm_chain, 1 hit
PF00117, GATase, 1 hit
PF02142, MGS, 1 hit
PF00185, OTCace, 1 hit
PF02729, OTCace_N, 1 hit
PRINTSiPR00100, AOTCASE
PR00098, CPSASE
SMARTiView protein in SMART
SM01096, CPSase_L_D3, 1 hit
SM01097, CPSase_sm_chain, 1 hit
SM00851, MGS, 1 hit
SUPFAMiSSF48108, SSF48108, 1 hit
SSF51338, SSF51338, 1 hit
SSF51556, SSF51556, 1 hit
SSF52021, SSF52021, 1 hit
SSF52317, SSF52317, 1 hit
SSF52335, SSF52335, 1 hit
SSF52440, SSF52440, 2 hits
SSF53671, SSF53671, 1 hit
TIGRFAMsiTIGR00670, asp_carb_tr, 1 hit
TIGR01369, CPSaseII_lrg, 1 hit
TIGR01368, CPSaseIIsmall, 1 hit
PROSITEiView protein in PROSITE
PS50975, ATP_GRASP, 2 hits
PS00097, CARBAMOYLTRANSFERASE, 1 hit
PS00866, CPSASE_1, 2 hits
PS00867, CPSASE_2, 2 hits
PS00482, DIHYDROOROTASE_1, 1 hit
PS00483, DIHYDROOROTASE_2, 1 hit
PS51855, MGS, 1 hit

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiU3JAV8_DANRE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: U3JAV8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 13, 2013
Last sequence update: November 13, 2013
Last modified: May 25, 2022
This is version 58 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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