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Protein

Sulfhydryl oxidase

Gene

QSOX2

Organism
Callithrix jacchus (White-tufted-ear marmoset)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2.UniRule annotation

Cofactori

FADUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandFADUniRule annotation, Flavoprotein

Names & Taxonomyi

Protein namesi
Recommended name:
Sulfhydryl oxidaseUniRule annotation (EC:1.8.3.2UniRule annotation)
Gene namesi
Name:QSOX2Imported
OrganismiCallithrix jacchus (White-tufted-ear marmoset)Imported
Taxonomic identifieri9483 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniCebidaeCallitrichinaeCallithrixCallithrix
Proteomesi
  • UP000008225 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei665 – 682HelicalSequence analysisAdd BLAST18

Keywords - Cellular componenti

Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 178ThioredoxinInterPro annotationAdd BLAST145
Domaini421 – 530ERV/ALR sulfhydryl oxidaseInterPro annotationAdd BLAST110

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00390000008045

Family and domain databases

Gene3Di1.20.120.310, 1 hit
InterProiView protein in InterPro
IPR036774 ERV/ALR_sulphydryl_oxid_sf
IPR017905 ERV/ALR_sulphydryl_oxidase
IPR036249 Thioredoxin-like_sf
IPR017937 Thioredoxin_CS
IPR013766 Thioredoxin_domain
PfamiView protein in Pfam
PF04777 Evr1_Alr, 1 hit
PF00085 Thioredoxin, 1 hit
SUPFAMiSSF52833 SSF52833, 1 hit
SSF69000 SSF69000, 1 hit
PROSITEiView protein in PROSITE
PS51324 ERV_ALR, 1 hit
PS00194 THIOREDOXIN_1, 1 hit
PS51352 THIOREDOXIN_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.iShow all

U3FXW8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAASGAAVAR CPRVGAGPAP GARRSPPPRA AGLPRLLVLL AAATAGPGTG
60 70 80 90 100
GAARLYRAGE DAVWVLDSGS VRGATANSSA AWLVQFYSSW CGHCVGYAPT
110 120 130 140 150
WRALAGDVRD WASAIRVAAL DCMEDKNQAV CHDYDIHFYP TFRYFKAFTK
160 170 180 190 200
EFTTGETFKG PDRELRTVRQ TMIDFLQNHT EGSWPPACPP LNPIQPSDVL
210 220 230 240 250
SLIDHRGSHY VAIVFESNSS YLGREVILDL IPYENIVVTR ALDGDKAFLE
260 270 280 290 300
KLGVSSVPSC FLIHPNGSCG LINVAKPFRA FFSSYLKSLP DVRKKPLSLP
310 320 330 340 350
EKPNKEENSE VVVWREFDKS KLYTADLESG LHYLLRVELA AHRSLAGAEL
360 370 380 390 400
KTLKDFVTVV AKLFPGRPPV RKLLETLQEW LASLPLDRIP YNAVLDLVNN
410 420 430 440 450
KMRISGIFLT NHIKWVGCQG SRPQLRGYPC SLWKLFHTLT VQASAHPDTL
460 470 480 490 500
VGTGFEDDPQ AVLQTVRRYI RTFFGCKECG EHFEEMAKES MDSVKTPDQA
510 520 530 540 550
ILWLWRKHNV VNGRLAGHPS EDPRFPKLQW PTPDLCPACH EEMKGLDSWD
560 570 580 590 600
EGHVLTFLKQ HYSRDNLLDT YSADQGDSGE GGPLARGEEE EKRLIPPDKS
610 620 630 640 650
HGDQDAQSVR PPSVLGPRPA LPESLRHRLD VRLQSLDGPK VHKQVEVAVP
660 670 680 690
FLGVGFSSLD MSLCVVLYVA SSLFLMVMYF FFRVRSRRWK VKYHHPAV
Length:698
Mass (Da):77,760
Last modified:November 13, 2013 - v1
Checksum:iF040D1D65A2EDC3A
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2R8M9D9A0A2R8M9D9_CALJA
Sulfhydryl oxidase
592Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GAMT01006362 mRNA Translation: JAB05499.1
GAMS01004267 mRNA Translation: JAB18869.1
GAMQ01000773 mRNA Translation: JAB41078.1
GAMP01001345 mRNA Translation: JAB51410.1

Genome annotation databases

EnsembliENSCJAT00000020850; ENSCJAP00000019728; ENSCJAG00000010708

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GAMT01006362 mRNA Translation: JAB05499.1
GAMS01004267 mRNA Translation: JAB18869.1
GAMQ01000773 mRNA Translation: JAB41078.1
GAMP01001345 mRNA Translation: JAB51410.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSCJAT00000020850; ENSCJAP00000019728; ENSCJAG00000010708

Phylogenomic databases

GeneTreeiENSGT00390000008045

Family and domain databases

Gene3Di1.20.120.310, 1 hit
InterProiView protein in InterPro
IPR036774 ERV/ALR_sulphydryl_oxid_sf
IPR017905 ERV/ALR_sulphydryl_oxidase
IPR036249 Thioredoxin-like_sf
IPR017937 Thioredoxin_CS
IPR013766 Thioredoxin_domain
PfamiView protein in Pfam
PF04777 Evr1_Alr, 1 hit
PF00085 Thioredoxin, 1 hit
SUPFAMiSSF52833 SSF52833, 1 hit
SSF69000 SSF69000, 1 hit
PROSITEiView protein in PROSITE
PS51324 ERV_ALR, 1 hit
PS00194 THIOREDOXIN_1, 1 hit
PS51352 THIOREDOXIN_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiU3FXW8_CALJA
AccessioniPrimary (citable) accession number: U3FXW8
Secondary accession number(s): F6XJX4
Entry historyiIntegrated into UniProtKB/TrEMBL: November 13, 2013
Last sequence update: November 13, 2013
Last modified: June 20, 2018
This is version 19 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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