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Protein

Inhibitor of growth protein

Gene

ING4

Organism
Callithrix jacchus (White-tufted-ear marmoset)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChromatin regulatorUniRule annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Inhibitor of growth proteinUniRule annotation
Gene namesi
Name:ING4Imported
OrganismiCallithrix jacchus (White-tufted-ear marmoset)Imported
Taxonomic identifieri9483 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniCebidaeCallitrichinaeCallithrixCallithrix

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotation

Interactioni

Subunit structurei

Interacts with H3K4me3 and to a lesser extent with H3K4me2.UniRule annotation

GO - Molecular functioni

Structurei

3D structure databases

SMRiU3EY84
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini193 – 242PHD-typeInterPro annotationAdd BLAST50

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili28 – 48Sequence analysisAdd BLAST21
Coiled coili97 – 117Sequence analysisAdd BLAST21

Domaini

The PHD-type zinc finger mediates the binding to H3K4me3.UniRule annotation

Sequence similaritiesi

Belongs to the ING family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR028647 ING4
IPR024610 ING_N_histone_binding
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR10333:SF40 PTHR10333:SF40, 1 hit
PfamiView protein in Pfam
PF12998 ING, 1 hit
SMARTiView protein in SMART
SM01408 ING, 1 hit
SM00249 PHD, 1 hit
SUPFAMiSSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS01359 ZF_PHD_1, 1 hit
PS50016 ZF_PHD_2, 1 hit

Sequencei

Sequence statusi: Complete.

U3EY84-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAGMYLEHY LDSIENLPFE LQRNFQLMRD LDQRTEDLKA EIDKLATEYM
60 70 80 90 100
SSARSLSSEE KLALLKQIQE AYGKCKEFGD DKVQLAMQTY EMVDKHIRRL
110 120 130 140 150
DTDLARFEAD LKEKQIESSD YDSSSSKEGR TQKEKKAARA RSKGKNSDEE
160 170 180 190 200
APKTAQKKLK LVRTSPEYGM PSVTFGSVHP SDVLDMPVDP NEPTYCLCHQ
210 220 230 240
VSYGEMIGCD NPDCSIEWFH FACVGLTTKP RGKWFCPRCS QERKKK
Length:246
Mass (Da):28,218
Last modified:November 13, 2013 - v1
Checksum:iAE5F98B0081B189B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GAMT01008813 mRNA Translation: JAB03048.1
GAMS01009147 mRNA Translation: JAB13989.1
GAMR01003076 mRNA Translation: JAB30856.1
RefSeqiXP_009001729.1, XM_009003481.2

Genome annotation databases

GeneIDi100404187

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GAMT01008813 mRNA Translation: JAB03048.1
GAMS01009147 mRNA Translation: JAB13989.1
GAMR01003076 mRNA Translation: JAB30856.1
RefSeqiXP_009001729.1, XM_009003481.2

3D structure databases

SMRiU3EY84
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100404187

Organism-specific databases

CTDi51147

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR028647 ING4
IPR024610 ING_N_histone_binding
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR10333:SF40 PTHR10333:SF40, 1 hit
PfamiView protein in Pfam
PF12998 ING, 1 hit
SMARTiView protein in SMART
SM01408 ING, 1 hit
SM00249 PHD, 1 hit
SUPFAMiSSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS01359 ZF_PHD_1, 1 hit
PS50016 ZF_PHD_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiU3EY84_CALJA
AccessioniPrimary (citable) accession number: U3EY84
Entry historyiIntegrated into UniProtKB/TrEMBL: November 13, 2013
Last sequence update: November 13, 2013
Last modified: March 28, 2018
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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