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Protein
Submitted name:

Calcium-binding mitochondrial carrier protein SCaMC-1 isoform 1

Gene

SLC25A24

Organism
Callithrix jacchus (White-tufted-ear marmoset)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi32 – 43PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi68 – 79PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi99 – 110PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

Keywordsi

Biological processTransportUniRule annotationSAAS annotation
LigandCalciumPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Calcium-binding mitochondrial carrier protein SCaMC-1 isoform 1Imported
Gene namesi
Name:SLC25A24Imported
OrganismiCallithrix jacchus (White-tufted-ear marmoset)Imported
Taxonomic identifieri9483 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniCebidaeCallitrichinaeCallithrixCallithrix

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 15Sequence analysisAdd BLAST15
ChainiPRO_501340241516 – 477Sequence analysisAdd BLAST462

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 54EF-handInterPro annotationAdd BLAST36
Domaini61 – 85EF-handInterPro annotationAdd BLAST25
Domaini86 – 121EF-handInterPro annotationAdd BLAST36
Domaini122 – 157EF-handInterPro annotationAdd BLAST36
Repeati192 – 278SolcarPROSITE-ProRule annotationAdd BLAST87
Repeati286 – 371SolcarPROSITE-ProRule annotationAdd BLAST86
Repeati383 – 471SolcarPROSITE-ProRule annotationAdd BLAST89

Sequence similaritiesi

Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG0036 Eukaryota
ENOG410XQ4P LUCA

Family and domain databases

Gene3Di1.50.40.10, 1 hit
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR002167 Graves_DC
IPR002067 Mit_carrier
IPR040062 Mitochondrial_carrier_protein
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
PANTHERiPTHR24089 PTHR24089, 1 hit
PfamiView protein in Pfam
PF13499 EF-hand_7, 2 hits
PF00153 Mito_carr, 3 hits
PRINTSiPR00928 GRAVESDC
PR00926 MITOCARRIER
SMARTiView protein in SMART
SM00054 EFh, 3 hits
SUPFAMiSSF103506 SSF103506, 1 hit
SSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 2 hits
PS50222 EF_HAND_2, 4 hits
PS50920 SOLCAR, 3 hits

Sequencei

Sequence statusi: Complete.

U3DLR7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLRWLLGFVL PTAACQDAEP STRYETLFQV LDRNGDGVVD IGELQEGLKN
60 70 80 90 100
LGIPLGQDAE EKIFTTGDVN KDGKLDFEEF MKYLKDHEKK MKLAFKSLDK
110 120 130 140 150
NNDGKIEASE IVQSLQTLGL TISEKQAELI LQSIDADGTM TVDWTEWRDY
160 170 180 190 200
FLFNPATDIE EIIRFWKHST GIDIGDSLTI PDEFTEDEKK SGQWWRQLLA
210 220 230 240 250
GGIAGAVSRT STAPLDRLKI MMQVHGSKSD KMNIFGGFRQ MVKEGGIRSL
260 270 280 290 300
WRGNGTNVIK IAPETAVKFW AYEQYKKLLT EEGQKVGTFE RFISGSMAGA
310 320 330 340 350
TAQTFIYPME VMKTRLAVGK TGQYSGIYNC AKKILKHEGV GAFYKGYVPN
360 370 380 390 400
LLGIIPYAGI DLAVYELLKS YWLDNFAKDS VNPGVVVLLG CGALSSTCGQ
410 420 430 440 450
LASYPLALVR TRMQAQAMLE GSPQLNMVGL FRRIISKEGI PGLYRGITPN
460 470
FMKVLPAVGI SYVVYENMKQ TLGVTQK
Length:477
Mass (Da):53,082
Last modified:November 13, 2013 - v1
Checksum:iC66B13BE0C808040
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GAMT01001156 mRNA Translation: JAB10705.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GAMT01001156 mRNA Translation: JAB10705.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0036 Eukaryota
ENOG410XQ4P LUCA

Family and domain databases

Gene3Di1.50.40.10, 1 hit
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR002167 Graves_DC
IPR002067 Mit_carrier
IPR040062 Mitochondrial_carrier_protein
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
PANTHERiPTHR24089 PTHR24089, 1 hit
PfamiView protein in Pfam
PF13499 EF-hand_7, 2 hits
PF00153 Mito_carr, 3 hits
PRINTSiPR00928 GRAVESDC
PR00926 MITOCARRIER
SMARTiView protein in SMART
SM00054 EFh, 3 hits
SUPFAMiSSF103506 SSF103506, 1 hit
SSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 2 hits
PS50222 EF_HAND_2, 4 hits
PS50920 SOLCAR, 3 hits
ProtoNetiSearch...

Entry informationi

Entry nameiU3DLR7_CALJA
AccessioniPrimary (citable) accession number: U3DLR7
Entry historyiIntegrated into UniProtKB/TrEMBL: November 13, 2013
Last sequence update: November 13, 2013
Last modified: November 7, 2018
This is version 30 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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