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Protein

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

Gene

NDUFA12

Organism
Callithrix jacchus (White-tufted-ear marmoset)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.UniRule annotation

GO - Molecular functioni

Keywordsi

Biological processElectron transport, Respiratory chainUniRule annotation, Transport
LigandUbiquinoneImported

Names & Taxonomyi

Protein namesi
Recommended name:
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12UniRule annotation
Gene namesi
Name:NDUFA12Imported
OrganismiCallithrix jacchus (White-tufted-ear marmoset)Imported
Taxonomic identifieri9483 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniCebidaeCallitrichinaeCallithrixCallithrix

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

Interactioni

Subunit structurei

Complex I is composed of 45 different subunits.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I NDUFA12 subunit family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3382 Eukaryota
ENOG4111XVR LUCA
OrthoDBiEOG091G0XDC

Family and domain databases

InterProiView protein in InterPro
IPR007763 NDUFA12
PANTHERiPTHR12910 PTHR12910, 1 hit
PfamiView protein in Pfam
PF05071 NDUFA12, 1 hit

Sequencei

Sequence statusi: Complete.

U3D7Y1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MELVEVLKRG LQQVTGHGGL RGYLRMLFRV NDVKIGTLVG EDKYGNKYYE
60 70 80 90 100
DNKQFFGRHR WVIYTTEMNG KNTFWDVDGS MVPPEWHRWL HSMTDDPPTV
110 120 130 140
KPLTPRKFIW TTHKFNVTGT PEQYVPYSTT RKKIQEWIPP STPYK
Length:145
Mass (Da):17,165
Last modified:November 13, 2013 - v1
Checksum:iF6239D5103B6E123
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GAMT01003941 mRNA Translation: JAB07920.1
GAMS01004837 mRNA Translation: JAB18299.1
GAMR01010626 mRNA Translation: JAB23306.1
GAMQ01007288 mRNA Translation: JAB34563.1
GAMP01007577 mRNA Translation: JAB45178.1

Similar proteinsi

Entry informationi

Entry nameiU3D7Y1_CALJA
AccessioniPrimary (citable) accession number: U3D7Y1
Entry historyiIntegrated into UniProtKB/TrEMBL: November 13, 2013
Last sequence update: November 13, 2013
Last modified: December 20, 2017
This is version 18 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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