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Protein
Submitted name:

Membrane metalloendopeptidase

Gene

MME

Organism
Callithrix jacchus (White-tufted-ear marmoset)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Protein family/group databases

MEROPSiM13.001

Names & Taxonomyi

Protein namesi
Submitted name:
Membrane metalloendopeptidaseImported
Submitted name:
NeprilysinImported
Gene namesi
Name:MMEImported
OrganismiCallithrix jacchus (White-tufted-ear marmoset)Imported
Taxonomic identifieri9483 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniCebidaeCallitrichinaeCallithrixCallithrix
Proteomesi
  • UP000008225 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei29 – 52HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi9483.ENSCJAP00000001671

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini79 – 483Peptidase_M13_NInterPro annotationAdd BLAST405
Domaini543 – 749Peptidase_M13InterPro annotationAdd BLAST207

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili269 – 289Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3624 Eukaryota
COG3590 LUCA
GeneTreeiENSGT00760000119162
KOiK01389
OMAiTATWRRC
OrthoDBiEOG091G025Y
TreeFamiTF315192

Family and domain databases

CDDicd08662 M13, 1 hit
Gene3Di3.40.390.10, 3 hits
InterProiView protein in InterPro
IPR024079 MetalloPept_cat_dom_sf
IPR029727 MME/CD10/NEP
IPR000718 Peptidase_M13
IPR018497 Peptidase_M13_C
IPR008753 Peptidase_M13_N
PANTHERiPTHR11733 PTHR11733, 1 hit
PTHR11733:SF114 PTHR11733:SF114, 1 hit
PfamiView protein in Pfam
PF01431 Peptidase_M13, 1 hit
PF05649 Peptidase_M13_N, 1 hit
PRINTSiPR00786 NEPRILYSIN

Sequencei

Sequence statusi: Complete.

U3D5D7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRSESQMDI TDINTPKPKK KQRWTPLEIS LSVLVLLLTI IAVTMIALYA
60 70 80 90 100
TYDDGICKSS DCIKSAARLI QNMDATAEPC TDFFKYACGG WLKRNVIPET
110 120 130 140 150
SSRYGNFDIL RDELEVVLKD VLQEPKTEDI VAVQKAKTLY RSCINESAID
160 170 180 190 200
SRGGGPLLKL LPDIYGWPVA TENWEQKYGA SWTAEKAIAQ LNSKYGKKVL
210 220 230 240 250
FNLFVGTDDK NSVNHVIHVD QPRLGLPSRD YYECTGIYKE ACTAYVDFMI
260 270 280 290 300
SVARLIRQEE KLPIDENQLA LEMNKVMELE KEIANATAKP EDRNDPMLLY
310 320 330 340 350
NKMTLAQLQS NFSLEINGKP FSWSNFTNEI MSTVNINIPN EEDVVVYAPE
360 370 380 390 400
YLTKLKPILT KYSARDLQNL MSWRFIMDLV SSLSRTYKES RNAFRKALYG
410 420 430 440 450
TTSETATWRR CANYVNGNME NAVGRLYVEA AFAGESKHVV EDLIAQIREV
460 470 480 490 500
FIQTLDDLTW MDAETKKRAE EKALAIKERI GYPDDIIADD NKLNNEYLEL
510 520 530 540 550
NYKEDEYFEN IIQNLKFSQS KQLKKLREKV DKDEWISGAA VVNAFYSSGR
560 570 580 590 600
NQIVFPAGIL QPPFFSAQQS NSLNYGGIGM VIGHEITHGF DDNGRNFNKD
610 620 630 640 650
GDLVDWWTQQ SASNFKEQSQ CMVYQYGNFS WDLAGGQHLN GINTLGENIA
660 670 680 690 700
DNGGIGQAYR AYQNYVKKNG EEKLLPGLDL NHKQLFFLNF AQVWCGTYRP
710 720 730 740 750
EYAVNSIKTD VHSPGNFRII GTLQNSAEFS EAFHCRKNSY MNPEKKCRVW
Length:750
Mass (Da):85,417
Last modified:November 13, 2013 - v1
Checksum:i89B5E476EB1047A1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GAMT01006926 mRNA Translation: JAB04935.1
GAMT01006925 mRNA Translation: JAB04936.1
GAMQ01001790 mRNA Translation: JAB40061.1
RefSeqiXP_002759515.1, XM_002759469.3
XP_002759517.1, XM_002759471.2
XP_008981879.1, XM_008983631.2
XP_008981880.1, XM_008983632.2
XP_008981881.1, XM_008983633.2
XP_008981882.1, XM_008983634.2
XP_008981883.1, XM_008983635.2
XP_008981884.1, XM_008983636.1

Genome annotation databases

EnsembliENSCJAT00000001775; ENSCJAP00000001671; ENSCJAG00000000959
GeneIDi100387438
KEGGicjc:100387438

Similar proteinsi

Entry informationi

Entry nameiU3D5D7_CALJA
AccessioniPrimary (citable) accession number: U3D5D7
Secondary accession number(s): F7CC38
Entry historyiIntegrated into UniProtKB/TrEMBL: November 13, 2013
Last sequence update: November 13, 2013
Last modified: July 18, 2018
This is version 28 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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