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Protein
Submitted name:

Mineralocorticoid receptor isoform 1

Gene

NR3C2

Organism
Callithrix jacchus (White-tufted-ear marmoset)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi599 – 674Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorSAAS annotationImported
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Mineralocorticoid receptor isoform 1Imported
Submitted name:
Nuclear receptor subfamily 3 group C member 2Imported
Gene namesi
Name:NR3C2Imported
OrganismiCallithrix jacchus (White-tufted-ear marmoset)Imported
Taxonomic identifieri9483 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniCebidaeCallitrichinaeCallithrixCallithrix
Proteomesi
  • UP000008225 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi9483.ENSCJAP00000004277

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini599 – 674Nuclear receptorInterPro annotationAdd BLAST76
Domaini725 – 963NR LBDInterPro annotationAdd BLAST239

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.SAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
GeneTreeiENSGT00760000118887
OMAiSKICLVC
OrthoDBiEOG091G0166
TreeFamiTF106510

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

U3BUE6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METKGYHSLP EGLDMERRWG QVSQAVEHSS LGSTERTDEN NYMEIVNVSC
60 70 80 90 100
VSGAIPNNST QGSSKEKHEL LPCLQQDNNR PGVLTSDIKT ELESKELSAT
110 120 130 140 150
VAESMGLYMD SVRDADYYEQ QNQQRSMSPA KIYQNVEQLV KFYKENGHRP
160 170 180 190 200
STLSCVNRPL RSFMSDSGSS VNGGVMRAIV RSPIMCHEKS PSVCSPLNMT
210 220 230 240 250
SSVCSPAGIN SVSSTTASFG SFPVHSPITQ GTPLTCSPNV ENRGSRSHSP
260 270 280 290 300
AHASNVGSPL SSPLSSMKSS ISSPPSHCSV KSPVSSPNNV TLRSSVSSPA
310 320 330 340 350
NINNSRCSVS SPSNTNNRST LSSPAASTVG SICSPVNNAF SYTASGTSAG
360 370 380 390 400
SSTSRDVVPS PDTQEKGAQE VPFPKTEEVE SAISNGVTGQ LNIVQYIKPE
410 420 430 440 450
PDGAFSSSCL GGNSKINSDS PFSVPIKQES TKHSCSGTSF KGNPTVNPFP
460 470 480 490 500
FMDGSYFSFM DDKDYYSLSG ILGPPVPGFD GNCEGSGFPV GIKQEPDDGS
510 520 530 540 550
YYPEASIPSS AIVGVNSGGQ SFHYRIGAQG TISLSRSARD QSFQHLSSFP
560 570 580 590 600
PVNTLVESWK SHGDLSSRRS DGYPVLEYIP ENVSSSTLRS VSTGSSRPSK
610 620 630 640 650
ICLVCGDEAS GCHYGVVTCG SCKVFFKRAV EGQHNYLCAG RNDCIIDKIR
660 670 680 690 700
RKNCPACRLQ KCLQAGMNLG ARKSKKLGKL KGIHEEQPQQ QQPPPPPPPP
710 720 730 740 750
QSPEEGTTYI APAKEPSVNT ALVPQLSTIS RALTPSPAMV LENIEPEVVY
760 770 780 790 800
AGYDNSKPDT AENLLSTLNR LAGKQMIQVV KWAKVLPGFK NLPLEDQITL
810 820 830 840 850
IQYSWMCLSS FALSWRSYKH TNSQFLYFAP DLVFNEEKMH QSAMYELCQG
860 870 880 890 900
MHQISLQFIR LQLTFEEYTI MKVLLLLSTV PKDGLKSQAA FEEMRTNYIK
910 920 930 940 950
ELRKMVTKCP NNSGQSWQRF YQLTKLLDSM HDLVNDLLEF CFYTFRESQA
960 970 980
LKVEFPAMLV EIISDQLPKV ESGNAKPLYF HRK
Length:983
Mass (Da):107,216
Last modified:November 13, 2013 - v1
Checksum:iBA04B35C7AB192E2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GAMS01006458 mRNA Translation: JAB16678.1
GAMP01004120 mRNA Translation: JAB48635.1
RefSeqiXP_008990814.1, XM_008992566.1

Genome annotation databases

EnsembliENSCJAT00000004508; ENSCJAP00000004277; ENSCJAG00000002360
GeneIDi100405081

Similar proteinsi

Entry informationi

Entry nameiU3BUE6_CALJA
AccessioniPrimary (citable) accession number: U3BUE6
Secondary accession number(s): F6WV84
Entry historyiIntegrated into UniProtKB/TrEMBL: November 13, 2013
Last sequence update: November 13, 2013
Last modified: July 18, 2018
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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