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Protein

Chromosomal replication initiator protein DnaA

Gene

dnaA

Organism
Propionibacterium acidifaciens F0233
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi186 – 193ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation
Biological processDNA replicationUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chromosomal replication initiator protein DnaAUniRule annotation
Gene namesi
Name:dnaAUniRule annotationImported
ORF Names:HMPREF0682_1423Imported
OrganismiPropionibacterium acidifaciens F0233Imported
Taxonomic identifieri553198 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaPropionibacterialesPropionibacteriaceaePropionibacterium
Proteomesi
  • UP000017052 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini178 – 307AAAInterPro annotationAdd BLAST130
Domaini391 – 460Bac_DnaA_CInterPro annotationAdd BLAST70

Sequence similaritiesi

Belongs to the DnaA family.UniRule annotationSAAS annotation

Phylogenomic databases

OrthoDBiPOG091H02FF

Family and domain databases

CDDicd06571 Bac_DnaA_C, 1 hit
Gene3Di1.10.1750.10, 1 hit
3.30.300.180, 1 hit
HAMAPiMF_00377 DnaA_bact, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR001957 Chromosome_initiator_DnaA
IPR020591 Chromosome_initiator_DnaA-like
IPR018312 Chromosome_initiator_DnaA_CS
IPR013317 DnaA
IPR013159 DnaA_C
IPR038454 DnaA_N_sf
IPR027417 P-loop_NTPase
IPR010921 Trp_repressor/repl_initiator
PANTHERiPTHR30050:SF2 PTHR30050:SF2, 1 hit
PfamiView protein in Pfam
PF00308 Bac_DnaA, 1 hit
PF08299 Bac_DnaA_C, 1 hit
PRINTSiPR00051 DNAA
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SM00760 Bac_DnaA_C, 1 hit
SUPFAMiSSF48295 SSF48295, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00362 DnaA, 1 hit
PROSITEiView protein in PROSITE
PS01008 DNAA, 1 hit

Sequencei

Sequence statusi: Complete.

U2PIJ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATEPGTSRN EPDFTRAWEH VLSECGTSGG AFLRNAKPLT VHESTMMVAV
60 70 80 90 100
PNDFTRERIE TKMRGALEEA LSDYYRRSMH LALTIEPDLE LDLRAPDHDD
110 120 130 140 150
EGTGEARREE SAPRFVPRKG APSLLLSESA GPSSSAPDPN GSEQRLNPRY
160 170 180 190 200
TFDNFVIGAS NRFAHAAAVA VAEAPGKAYN PLMIYGESGL GKTHLLHALG
210 220 230 240 250
HYVIDYYEGV RVKYVSTEEM TNEFINAVGE NRTVEFRRKY RDDVDVLLVD
260 270 280 290 300
DIQFLEGKTQ TQEEFFYTFN ALHNAQKQIV LTSDRPPKAL EQLESRLRSR
310 320 330 340 350
FEWGLITDIQ PPDLETRIAI LQRKALAEQL LVPADVLEFI GSRIQTNIRE
360 370 380 390 400
LEGALIRVTA FASLNREPVT HDLADRVLAD LIPDGTDAEV SAQLIIAETA
410 420 430 440 450
GYFDVSVEAL SGSSRTQPLV LARQIAMYLC RELTDLSLPK IGQEFGGKDH
460 470 480
TTVMHADRKI RELMRKQRSV FNQVSELTNR IKQAAARG
Length:488
Mass (Da):54,570
Last modified:November 13, 2013 - v1
Checksum:i9708E46DD1E09E02
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACVN02000307 Genomic DNA Translation: ERK50380.1
RefSeqiWP_021798757.1, NZ_ACVN02000307.1

Genome annotation databases

EnsemblBacteriaiERK50380; ERK50380; HMPREF0682_1423

Similar proteinsi

Entry informationi

Entry nameiU2PIJ1_9ACTN
AccessioniPrimary (citable) accession number: U2PIJ1
Entry historyiIntegrated into UniProtKB/TrEMBL: November 13, 2013
Last sequence update: November 13, 2013
Last modified: July 18, 2018
This is version 37 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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