Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 31 (12 Aug 2020)
Sequence version 1 (13 Nov 2013)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Alpha-L-rhamnosidase

Gene

BN863_22170

Organism
Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Alpha-L-rhamnosidase that may be involved in ulvan degradation (Probable). Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable).1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • Hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides.By similarity EC:3.2.1.40

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei520L-rhamnoseBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei525Proton donorBy similarity1
Binding sitei532L-rhamnoseBy similarity1
Binding sitei594L-rhamnoseBy similarity1
Active sitei809Proton acceptorBy similarity1
Binding sitei826L-rhamnoseBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosidase, Hydrolase

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Alpha-L-rhamnosidase1 Publication (EC:3.2.1.40By similarity)
Alternative name(s):
Glycosyl hydrolase 78 family protein P28Curated
Short name:
P28_GH781 Publication
Polysaccharide utilization locus H protein P281 Publication
Short name:
PUL H protein P28
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:BN863_22170
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiFormosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1347342 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeFormosa
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000016160 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 21Sequence analysisAdd BLAST21
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500459113022 – 952Alpha-L-rhamnosidaseAdd BLAST931

Keywords - PTMi

Lipoprotein

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

By ulvan and rhamnose.1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
1347342.BN863_22170

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
T2KPL4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni524 – 525L-rhamnose bindingBy similarity2

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glycosyl hydrolase 78 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG3408, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002926_1_1_10

Database of Orthologous Groups

More...
OrthoDBi
170130at2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.50.10.10, 1 hit
2.60.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008928, 6-hairpin_glycosidase_sf
IPR012341, 6hp_glycosidase-like_sf
IPR016007, Alpha_rhamnosid
IPR035396, Bac_rhamnosid6H
IPR035398, Bac_rhamnosid_C
IPR013737, Bac_rhamnosid_N
IPR013783, Ig-like_fold
IPR008902, Rhamnosid_concanavalin

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05592, Bac_rhamnosid, 1 hit
PF17389, Bac_rhamnosid6H, 1 hit
PF17390, Bac_rhamnosid_C, 1 hit
PF08531, Bac_rhamnosid_N, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF010631, A-rhamnsds, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48208, SSF48208, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

T2KPL4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKYNKLLFSL LLLAVFCFSC KEEQKLQTSL DFDKVLLNAK SNPIAIESES
60 70 80 90 100
PLFSWIIKAE GFGKSQSAYH ILVASSLDKL DETHADVWNS NKVESSKSTF
110 120 130 140 150
VKYEGKELKA ATRYYWKVKV WDKSNQESNW SEPQYFQMGL LDESNWGEAK
160 170 180 190 200
WITLTNDTRT SEYRFREYKT GRMEQPIQVD GFAASYFRNK INLNKEVDNA
210 220 230 240 250
QVYICGLGYY EFFLNGEKVG DHVLDPAPSN YDKQAYYVNY DITEQLNSGE
260 270 280 290 300
NALGIILGNG FYGQNISWKN DPESDRDLAY GPPTVRVLLK LKYKDGTESE
310 320 330 340 350
FFSDETWKES TGPIVFNNIY GGDTYDARFE LGDWTSTNYD DSSWGFAKET
360 370 380 390 400
APEIKNISAQ QIPAIKKLQD YEPQNVFKGS DGEWIVDFGQ NIAGWVKLNV
410 420 430 440 450
SEKEGQLIEV ITTEALLTNG RDIFPGSTGG GANGMAQIYQ YICKGDGQES
460 470 480 490 500
WEPKFSYHGF RYAKIKGVST KPDADMIKAV LVATDIQETG SFECSDDLFN
510 520 530 540 550
KMHNISKWTI VDNVHGIPED CPHREKCGWL GDAHAFCEYA LYNYDMYDFY
560 570 580 590 600
KKYMEDIRTQ MLPTKGHNNP ELKFQVPTMI APGKRTSSYA KIDWGVATMY
610 620 630 640 650
LPWYNYLYYG DDAIVNEYYP EMKDLTNFYL NFKGENGIMQ DGMGDWCPPR
660 670 680 690 700
WDRRTNPEAM ECDPIISANA YFYDVLGIME TFAKMNNDGA FQSEMKAEKE
710 720 730 740 750
ALKDAFNKAF LVEIPNTDFK WYQSQTATVQ ALQFGMVPEE EIENVVNGLE
760 770 780 790 800
YDIVEVKGGH HSTGIHGNRY IYTVLSKYGK ADLAYRILTT PDFPSQTYIM
810 820 830 840 850
NSGFTTWPER QFEWETMEGP TNSLNHPMHS GFSAYFFESL GGIKSSTKEA
860 870 880 890 900
GYKQFIVNPE FPSQITQTKV SVPTPYGDIK NDWSFEEGKL SMTLEIPFNT
910 920 930 940 950
EANLVLNQAE LESLIINGKT FQNLQKNTKS VTLQGSNVIL GSGKYKILYN

KR
Length:952
Mass (Da):108,674
Last modified:November 13, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4EF328B1CC2E1EA2
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
HG315671 Genomic DNA Translation: CDF79929.1

NCBI Reference Sequences

More...
RefSeqi
WP_038530525.1, NZ_HG315671.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
CDF79929; CDF79929; BN863_22170

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1347342.6.peg.2224

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HG315671 Genomic DNA Translation: CDF79929.1
RefSeqiWP_038530525.1, NZ_HG315671.1

3D structure databases

SMRiT2KPL4
ModBaseiSearch...

Protein-protein interaction databases

STRINGi1347342.BN863_22170

Genome annotation databases

EnsemblBacteriaiCDF79929; CDF79929; BN863_22170
PATRICifig|1347342.6.peg.2224

Phylogenomic databases

eggNOGiCOG3408, Bacteria
HOGENOMiCLU_002926_1_1_10
OrthoDBi170130at2

Family and domain databases

Gene3Di1.50.10.10, 1 hit
2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR008928, 6-hairpin_glycosidase_sf
IPR012341, 6hp_glycosidase-like_sf
IPR016007, Alpha_rhamnosid
IPR035396, Bac_rhamnosid6H
IPR035398, Bac_rhamnosid_C
IPR013737, Bac_rhamnosid_N
IPR013783, Ig-like_fold
IPR008902, Rhamnosid_concanavalin
PfamiView protein in Pfam
PF05592, Bac_rhamnosid, 1 hit
PF17389, Bac_rhamnosid6H, 1 hit
PF17390, Bac_rhamnosid_C, 1 hit
PF08531, Bac_rhamnosid_N, 1 hit
PIRSFiPIRSF010631, A-rhamnsds, 1 hit
SUPFAMiSSF48208, SSF48208, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPLH28_FORAG
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: T2KPL4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 16, 2019
Last sequence update: November 13, 2013
Last modified: August 12, 2020
This is version 31 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again