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Protein

50S ribosomal protein L5

Gene

rplE

Organism
Variovorax paradoxus B4
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal proteinUniRule annotationImported, RNA-binding, rRNA-bindingUniRule annotation, tRNA-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L5UniRule annotation
Gene namesi
Name:rplEUniRule annotationImported
ORF Names:VAPA_1c52500Imported
OrganismiVariovorax paradoxus B4Imported
Taxonomic identifieri1246301 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeVariovorax
Proteomesi
  • UP000016223 Componenti: Chromosome 1

Subcellular locationi

GO - Cellular componenti

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.UniRule annotation

Structurei

3D structure databases

SMRiT1XHC1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 80Ribosomal_L5InterPro annotationAdd BLAST57
Domaini84 – 177Ribosomal_L5_CInterPro annotationAdd BLAST94

Sequence similaritiesi

Belongs to the universal ribosomal protein uL5 family.UniRule annotation

Phylogenomic databases

KOiK02931
OrthoDBiPOG091H007J

Family and domain databases

Gene3Di3.30.1440.10, 1 hit
HAMAPiMF_01333_B Ribosomal_L5_B, 1 hit
InterProiView protein in InterPro
IPR002132 Ribosomal_L5
IPR020930 Ribosomal_L5_bac-type
IPR031309 Ribosomal_L5_C
IPR020929 Ribosomal_L5_CS
IPR022803 Ribosomal_L5_dom_sf
IPR031310 Ribosomal_L5_N
PANTHERiPTHR11994 PTHR11994, 1 hit
PfamiView protein in Pfam
PF00281 Ribosomal_L5, 1 hit
PF00673 Ribosomal_L5_C, 1 hit
PIRSFiPIRSF002161 Ribosomal_L5, 1 hit
SUPFAMiSSF55282 SSF55282, 1 hit
PROSITEiView protein in PROSITE
PS00358 RIBOSOMAL_L5, 1 hit

Sequencei

Sequence statusi: Complete.

T1XHC1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MARLQQHYRE KIAKDLTEKF GYKSPMQVPR LTKITLNMGV GEAVADKKVL
60 70 80 90 100
DNAVADLTKI AGQKPVVTKS KKAIAGFKIR ENQPIGCMVT LRGVQMYEFL
110 120 130 140 150
DRFVTIALPR VRDFRGISGR AFDGRGNYNI GVKEQIIFPE IEYDKVDALR
160 170
GLNISITTTA KTDEEAKALL AGFRFPFKN
Length:179
Mass (Da):20,097
Last modified:November 13, 2013 - v1
Checksum:i52453D414EA4B313
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003911 Genomic DNA Translation: AGU52302.1
RefSeqiWP_013544114.1, NC_022247.1

Genome annotation databases

EnsemblBacteriaiAGU52302; AGU52302; VAPA_1c52500
GeneIDi29719609
KEGGivpd:VAPA_1c52500
PATRICifig|1246301.3.peg.5257

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003911 Genomic DNA Translation: AGU52302.1
RefSeqiWP_013544114.1, NC_022247.1

3D structure databases

SMRiT1XHC1
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAGU52302; AGU52302; VAPA_1c52500
GeneIDi29719609
KEGGivpd:VAPA_1c52500
PATRICifig|1246301.3.peg.5257

Phylogenomic databases

KOiK02931
OrthoDBiPOG091H007J

Family and domain databases

Gene3Di3.30.1440.10, 1 hit
HAMAPiMF_01333_B Ribosomal_L5_B, 1 hit
InterProiView protein in InterPro
IPR002132 Ribosomal_L5
IPR020930 Ribosomal_L5_bac-type
IPR031309 Ribosomal_L5_C
IPR020929 Ribosomal_L5_CS
IPR022803 Ribosomal_L5_dom_sf
IPR031310 Ribosomal_L5_N
PANTHERiPTHR11994 PTHR11994, 1 hit
PfamiView protein in Pfam
PF00281 Ribosomal_L5, 1 hit
PF00673 Ribosomal_L5_C, 1 hit
PIRSFiPIRSF002161 Ribosomal_L5, 1 hit
SUPFAMiSSF55282 SSF55282, 1 hit
PROSITEiView protein in PROSITE
PS00358 RIBOSOMAL_L5, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiT1XHC1_VARPD
AccessioniPrimary (citable) accession number: T1XHC1
Entry historyiIntegrated into UniProtKB/TrEMBL: November 13, 2013
Last sequence update: November 13, 2013
Last modified: June 20, 2018
This is version 26 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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