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Protein
Submitted name:

Uncharacterized protein

Gene

20212157

Organism
Helobdella robusta (Californian leech)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi88 – 95ATPPROSITE-ProRule annotation8

GO - Molecular functioni

  • ATPase activity Source: GO_Central
  • ATP binding Source: UniProtKB-UniRule
  • microtubule binding Source: GO_Central
  • microtubule motor activity Source: GO_Central

GO - Biological processi

Keywordsi

Molecular functionMotor proteinPROSITE-ProRule annotationSAAS annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:20212157Imported
ORF Names:HELRODRAFT_192110Imported
OrganismiHelobdella robusta (Californian leech)Imported
Taxonomic identifieri6412 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaAnnelidaClitellataHirudineaHirudinidaGlossiphoniiformesGlossiphoniidaeHelobdella
Proteomesi
  • UP000015101 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 235Kinesin motorInterPro annotationAdd BLAST227

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili329 – 363Sequence analysisAdd BLAST35
Coiled coili371 – 402Sequence analysisAdd BLAST32
Coiled coili482 – 551Sequence analysisAdd BLAST70
Coiled coili558 – 641Sequence analysisAdd BLAST84
Coiled coili649 – 683Sequence analysisAdd BLAST35
Coiled coili735 – 755Sequence analysisAdd BLAST21
Coiled coili765 – 792Sequence analysisAdd BLAST28
Coiled coili840 – 860Sequence analysisAdd BLAST21
Coiled coili901 – 945Sequence analysisAdd BLAST45

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

KOiK10395
OMAiACKEGSH
OrthoDBiEOG091G02I4

Family and domain databases

Gene3Di3.40.850.10, 1 hit
InterProiView protein in InterPro
IPR027640 Kinesin-like_fam
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase
PANTHERiPTHR24115 PTHR24115, 2 hits
PfamiView protein in Pfam
PF00225 Kinesin, 1 hit
PRINTSiPR00380 KINESINHEAVY
SMARTiView protein in SMART
SM00129 KISc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50067 KINESIN_MOTOR_2, 1 hit

Sequencei

Sequence statusi: Complete.

T1FTL0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGDSSRIIPV KVAVRCRPLI QKEENEGCQG CLQFVPAEPQ LIVGKDKAFT
60 70 80 90 100
FDYVFNPSTS QQTVYSVAVS PLVKGLFKGY NATVLAYGQT GSGKTFSMGG
110 120 130 140 150
GYGVCMETNE DAVGIIPRVI RDLFEGISKM QDKFEFIIKV SYLELYKEDL
160 170 180 190 200
LDLFVPVQKR EKDQVVIRDD VSGGIKLTGM SEIEVHTYEE TMRALEEGSQ
210 220 230 240 250
GRTIGATAMN NQSSRSHAIF TIHLDRKSKL DRHKHQQGAA GTWECDQRTG
260 270 280 290 300
RGVIGQEGPH PIQRQQVDQA PPSTKFLRVI IKGNLSWDMH IDSLSKKINK
310 320 330 340 350
TIGVINKIKV QELQSNGVAA NKRISIGGVE METEQYRTII EKNRKLEDEN
360 370 380 390 400
RHLVNELQIV ITQNTEMMDK VVRTEVARDK MKEQLDDLKE QALKEMECLK
410 420 430 440 450
ECQLKEDTSM QTSALSPEVI DQQLSIMIKF KDKLCQIETG DVDERNNMND
460 470 480 490 500
DEDNTKLDDL ASPGEADGQQ ADELKSRHVL RQAQLNRELQ NLNNMLHRKQ
510 520 530 540 550
ELATQMQSNE KQMQEMKEQY EQQMKEMETE VEKLQKEKEE AVVMMHSLKS
560 570 580 590 600
NAANSKLAEQ RRKRVQELES QIQELKRKMS EQMRMLKMKE QNEKQVEKLN
610 620 630 640 650
QEIISMKQQR VKLMNQLKDD AEQFRKMKAE MTKEVLQLKS QDRKRQAEMA
660 670 680 690 700
KLERQHVNQQ VVLKRKAEEA AAANNRLKEV LMRQKMVMDD RNKKQEAADL
710 720 730 740 750
SGAGARIKKL IGDEMDLMVS VEEARIHLNQ QMSSRKEMNE QATCIRNKLN
760 770 780 790 800
IHENQVSECM SDEEKSSLAL QLKELEQQIE LCTVQIADLQ QKLIDADQDE
810 820 830 840 850
KCKSRWDNIH TIVESKIAIK FLLNMAVSLK VEGNKKNGEM EDLKAMCKEL
860 870 880 890 900
TQMNEKMQEG TFRFKLKYEQ DMCDLRKENE SKVLYLLSQM KNNKNFGSRS
910 920 930 940 950
EVKESERIEE LKKRIEFQEK EIEKFRAMEE ELNNKTEVIN NLRREMTKKQ
960 970 980 990 1000
YNLTMMRGEG TLLPTNIEAD IKTEFFNPPT LTDRIRKRPT KRRSNSSEEE
1010 1020 1030 1040 1050
DNEVTSDEFE DEDDVTKDPS YRSGLTPAPA RQRSRQASKA PQAVDSSSSS
1060 1070 1080 1090 1100
SSLFNRTFIT SDNGVAPTAL PPKKKVGERR KKTGSSKNEN NKPLDSTGGS
1110 1120 1130
NPPIDLSEVG VNSFGKKRKL QPLKSATYFT DQI
Length:1,133
Mass (Da):130,004
Last modified:October 16, 2013 - v1
Checksum:i45FF2E5223658E9D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AMQM01004767 Genomic DNA No translation available.
KB096676 Genomic DNA Translation: ESO03085.1
RefSeqiXP_009018778.1, XM_009020530.1

Genome annotation databases

EnsemblMetazoaiHelroT192110; HelroP192110; HelroG192110
GeneIDi20212157
KEGGihro:HELRODRAFT_192110

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AMQM01004767 Genomic DNA No translation available.
KB096676 Genomic DNA Translation: ESO03085.1
RefSeqiXP_009018778.1, XM_009020530.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiHelroT192110; HelroP192110; HelroG192110
GeneIDi20212157
KEGGihro:HELRODRAFT_192110

Organism-specific databases

CTDi20212157

Phylogenomic databases

KOiK10395
OMAiACKEGSH
OrthoDBiEOG091G02I4

Family and domain databases

Gene3Di3.40.850.10, 1 hit
InterProiView protein in InterPro
IPR027640 Kinesin-like_fam
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase
PANTHERiPTHR24115 PTHR24115, 2 hits
PfamiView protein in Pfam
PF00225 Kinesin, 1 hit
PRINTSiPR00380 KINESINHEAVY
SMARTiView protein in SMART
SM00129 KISc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50067 KINESIN_MOTOR_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiT1FTL0_HELRO
AccessioniPrimary (citable) accession number: T1FTL0
Entry historyiIntegrated into UniProtKB/TrEMBL: October 16, 2013
Last sequence update: October 16, 2013
Last modified: November 7, 2018
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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