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Entry version 30 (17 Jun 2020)
Sequence version 1 (16 Oct 2013)
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Protein
Submitted name:

Uncharacterized protein

Gene

20211335

Organism
Helobdella robusta (Californian leech)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:20211335Imported
ORF Names:HELRODRAFT_189670Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHelobdella robusta (Californian leech)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6412 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaSpiraliaLophotrochozoaAnnelidaClitellataHirudineaHirudinidaGlossiphoniiformesGlossiphoniidaeHelobdella
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000015101 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 89DisorderedSequence analysisAdd BLAST89
Regioni564 – 607DisorderedSequence analysisAdd BLAST44

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili832 – 852Sequence analysisAdd BLAST21
Coiled coili863 – 883Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi18 – 77PolyampholyteSequence analysisAdd BLAST60
Compositional biasi588 – 607PolyampholyteSequence analysisAdd BLAST20

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_276739_0_0_1

Database of Orthologous Groups

More...
OrthoDBi
117859at2759

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

T1FR88-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSTNGRAGYC TTIEDTQGVH PRKLKLIKQK ASQDTKDDLS SENEEQQRVS
60 70 80 90 100
QDTKDDLSSK DEEHFNTEEE KQDSDSGSQD SETSTTYGIS IPTLSQSGVY
110 120 130 140 150
KATMKAGEKL KEHFIETLRN EKWSLHFDGK HIKNTEYQVV VLKNENREVK
160 170 180 190 200
LAVLALINGK GETIFKGIKT VLDEYKLWPA IKLIISDTTS ANTGKSVGAV
210 220 230 240 250
TRLQKHFVML GLDKPLYIGC QHHVLDTLLK HVMNDYFEAA TTSPNLNYWF
260 270 280 290 300
ISRITEEYQQ LKASFDNSGD ALKEEEEVVW RDDMAFLHHL ITCYRQFKKT
310 320 330 340 350
GCFPKSAEDQ SSCDFISGTW SDIWFSGQVY NEDNLAAVCK NHSKAIKTLR
360 370 380 390 400
TFWSVEPTPI PTQRSKQYCS VCSYATCCLP AYRKHIKAMH AYKSVNTLLF
410 420 430 440 450
LKKSSSHHPA AKFVNRTELY CQCGYASNQG NVMACHMVAC MKLTCYTSQP
460 470 480 490 500
AKSQDPYIEY NYADDFLYMN RHEVKQEDEE SCVSYGMQTG SSPSTNRKSR
510 520 530 540 550
CMIDKGREPT PVEMCRSIIE DVLDCVFPVE TVVGECLDEL LNRTFSTIRK
560 570 580 590 600
IDKRDSLKIA RERKAMRKKR RNSVPRRAIQ QQHTTTHEAD DVSIKTEPGD
610 620 630 640 650
ECTDDNNNVI DEHAVYTSGN VIGEIIDDVR EGATEDEERD FEVKVEMEES
660 670 680 690 700
GTDSGISKVN ASLECNEHVT VCSDPADVSD KVAYDVVPGE TASLINSVDY
710 720 730 740 750
DRDDNVTANP DSHTENSETC FQDEDAEFVK KEVDHVENGY NPVEMNADDE
760 770 780 790 800
IDCIEMSQAV DCVGVNRNDD VGDEREGGIG ESFQKEENVC VEDNSDCDEM
810 820 830 840 850
NENDGAGIGN DCDENEDGCD KKNEDDCVEN ENDCVEIEND CIENENDCIE
860 870 880 890 900
NENGCDKKNE NDCDENENDC VEIENDCDKE NEDDCIENGN NCVENDCIEK
910 920 930 940 950
ESYHDKKNDG CVESENNCAA NACVENKNDY DERNENNCVE DEYDCDIKNN
960 970 980 990 1000
VGCIENENDC VEKNDDDCYE KNEDECVAEN EVNLDAVANA QSVNVGKMEP
1010 1020 1030 1040 1050
DDTGDNDCDS FFGEVGSRDK NLKSVEDDDD ILLSDHSGDH IAMNNSSTVG
1060 1070 1080 1090 1100
DVHGLNEVED CDANCNDDAG ADDLNCATEL QKGGCKGDDD CKKCSDDESE
1110 1120 1130 1140
IMLSDVGENT IQKETRLSLS ETNGDYDMDC DVDDDVLIDV DPYVEEAID
Length:1,149
Mass (Da):129,002
Last modified:October 16, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8B7FE39C954D4AA7
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AMQM01001996 Genomic DNA No translation available.
KB097639 Genomic DNA Translation: ESN93067.1

NCBI Reference Sequences

More...
RefSeqi
XP_009029323.1, XM_009031075.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
HelroT189670; HelroP189670; HelroG189670

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
20211335

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hro:HELRODRAFT_189670

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AMQM01001996 Genomic DNA No translation available.
KB097639 Genomic DNA Translation: ESN93067.1
RefSeqiXP_009029323.1, XM_009031075.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblMetazoaiHelroT189670; HelroP189670; HelroG189670
GeneIDi20211335
KEGGihro:HELRODRAFT_189670

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
20211335

Phylogenomic databases

HOGENOMiCLU_276739_0_0_1
OrthoDBi117859at2759

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiT1FR88_HELRO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: T1FR88
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 16, 2013
Last sequence update: October 16, 2013
Last modified: June 17, 2020
This is version 30 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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Main funding by: National Institutes of Health

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