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Protein

Malic enzyme

Gene

20195180

Organism
Helobdella robusta (Californian leech)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

Mg2+UniRule annotation, Mn2+UniRule annotationNote: Divalent metal cations. Prefers magnesium or manganese.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei51Proton donorUniRule annotation1
Active sitei122Proton acceptorUniRule annotation1
Metal bindingi194Divalent metal cationUniRule annotation1
Metal bindingi195Divalent metal cationUniRule annotation1
Metal bindingi218Divalent metal cationUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandMetal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Malic enzymeUniRule annotation
Gene namesi
Name:20195180Imported
ORF Names:HELRODRAFT_110490Imported
OrganismiHelobdella robusta (Californian leech)Imported
Taxonomic identifieri6412 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaAnnelidaClitellataHirudineaRhynchobdellidaGlossiphoniidaeHelobdella
Proteomesi
  • UP000015101 Componenti: Unassembled WGS sequence

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini28 – 209malicInterPro annotationAdd BLAST182
Domaini219 – 472Malic_MInterPro annotationAdd BLAST254

Sequence similaritiesi

Belongs to the malic enzymes family.UniRule annotation

Phylogenomic databases

KOiK00029
OMAiAGVSICK
OrthoDBiEOG09371HAU

Family and domain databases

Gene3Di3.40.50.10380, 1 hit
InterProiView protein in InterPro
IPR015884 Malic_enzyme_CS
IPR012301 Malic_N_dom
IPR037062 Malic_N_dom_sf
IPR012302 Malic_NAD-bd
IPR001891 Malic_OxRdtase
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF00390 malic, 1 hit
PF03949 Malic_M, 1 hit
PIRSFiPIRSF000106 ME, 1 hit
PRINTSiPR00072 MALOXRDTASE
SMARTiView protein in SMART
SM01274 malic, 1 hit
SM00919 Malic_M, 1 hit
SUPFAMiSSF51735 SSF51735, 1 hit
PROSITEiView protein in PROSITE
PS00331 MALIC_ENZYMES, 1 hit

Sequencei

Sequence statusi: Complete.

T1EF28-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQMDYIVNN LKNFSSSVEK YVHLMNIYQQ NEKLFYYLII NKVELVMPII
60 70 80 90 100
YTPTIGQICQ QFGSLFDNPH GLYVRYTDIG QIKSKLQQWP EKKIKAICLT
110 120 130 140 150
DGERILGLGD LGANGLGICI GKMMLYTACA KISPHICLPL CIDIGTNNAS
160 170 180 190 200
LLKSEHYKGY KKKRLEGKRY LEFMDEFMEA ATSLYGKDVI FHFEDFGNHN
210 220 230 240 250
AFELLERYKN KYCSFNDDIQ GTAAVTLAGL LVCSQIVDKR LFEQKFLFLG
260 270 280 290 300
AGEAAIGIAT LLVAAMKSDG ISEKEALKCI WMFDSKGLIV TSRAPETLTA
310 320 330 340 350
NKQRFAKNFQ AVDDFEEAVN LIKPDAIIGV AAIAGAFTQG VLEKMASNHK
360 370 380 390 400
HPIIFALSNP TCKSECTAAQ AYKTTKGKCL FASGSPFEPI TIKKKVFKPS
410 420 430 440 450
QCNNAYIFPS LVLGVMSAKV SIITDELFLC AAKLLSKQVT ADEMKEGILF
460 470 480 490 500
PPLSRMQEIS MTTALSMIDY VIKNKLTTSV DANSRRDALV SAHLYNADYH
510
CPTDNKLAEA F
Length:511
Mass (Da):56,858
Last modified:October 16, 2013 - v1
Checksum:i60644D14028636E2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AMQM01003473 Genomic DNA No translation available.
KB096183 Genomic DNA Translation: ESO07551.1
RefSeqiXP_009014162.1, XM_009015914.1

Genome annotation databases

EnsemblMetazoaiHelroT110490; HelroP110490; HelroG110490
GeneIDi20195180
KEGGihro:HELRODRAFT_110490

Similar proteinsi

Entry informationi

Entry nameiT1EF28_HELRO
AccessioniPrimary (citable) accession number: T1EF28
Entry historyiIntegrated into UniProtKB/TrEMBL: October 16, 2013
Last sequence update: October 16, 2013
Last modified: March 28, 2018
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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