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Entry version 14 (31 Jul 2019)
Sequence version 1 (16 Oct 2013)
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Protein
Submitted name:

Uncharacterized protein

Gene

TGME49_225690

Organism
Toxoplasma gondii (strain ATCC 50611 / Me49)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:TGME49_225690Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiToxoplasma gondii (strain ATCC 50611 / Me49)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri508771 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaSarcocystidaeToxoplasma
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001529 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

PTM databases

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
S8G5U5

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 20DisorderedSequence analysisAdd BLAST20
Regioni97 – 126DisorderedSequence analysisAdd BLAST30
Regioni190 – 283DisorderedSequence analysisAdd BLAST94
Regioni314 – 355DisorderedSequence analysisAdd BLAST42
Regioni381 – 413DisorderedSequence analysisAdd BLAST33
Regioni756 – 864DisorderedSequence analysisAdd BLAST109
Regioni1000 – 1032DisorderedSequence analysisAdd BLAST33
Regioni1055 – 1120DisorderedSequence analysisAdd BLAST66
Regioni1340 – 1377DisorderedSequence analysisAdd BLAST38
Regioni1530 – 1561DisorderedSequence analysisAdd BLAST32
Regioni1589 – 1624DisorderedSequence analysisAdd BLAST36

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi101 – 126PolarSequence analysisAdd BLAST26
Compositional biasi211 – 228PolyampholyteSequence analysisAdd BLAST18
Compositional biasi234 – 262PolarSequence analysisAdd BLAST29
Compositional biasi314 – 354PolarSequence analysisAdd BLAST41
Compositional biasi394 – 408PolyampholyteSequence analysisAdd BLAST15
Compositional biasi756 – 820PolarSequence analysisAdd BLAST65
Compositional biasi824 – 841PolyampholyteSequence analysisAdd BLAST18
Compositional biasi846 – 864PolarSequence analysisAdd BLAST19
Compositional biasi1000 – 1021PolarSequence analysisAdd BLAST22
Compositional biasi1056 – 1084PolyampholyteSequence analysisAdd BLAST29
Compositional biasi1091 – 1120PolyampholyteSequence analysisAdd BLAST30
Compositional biasi1344 – 1359PolarSequence analysisAdd BLAST16
Compositional biasi1363 – 1377AcidicSequence analysisAdd BLAST15

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

S8G5U5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALPRLPSKE SNALTRHDSS NTAYFQDYWS ENSSDSGLSQ GQDNACTPLC
60 70 80 90 100
GNGGRVRGFQ ASVVVPPPAP SPGHQTGQFT TLSHPSQYET VTAAHEGGGV
110 120 130 140 150
PQHQQESSLH HSSVCHIPPG SQCSPLQRSA VDLTSASAGG HSPSGYSRPQ
160 170 180 190 200
QLPIRDHLSS QANSLFVSAA NGHLVTQSQG QAKVENPTNH IQPTLAHNGD
210 220 230 240 250
AGNPASRGTG AERPETKKGK RSQGKKAGEG ASRGKGTPQN TASKTKGNEQ
260 270 280 290 300
QPQGASGKQD ASKQKRTTLK RNPAGKPELA GVSAKSLPVG DASMGAEAAL
310 320 330 340 350
GVAISADYLK RNQQEDSGVA PSPSEAAVTT QSGGEGSRIS AGISPAQNLP
360 370 380 390 400
GSSAAGASKG VVALAHDITP GWGMLPAEAQ HYSATTSQQQ REWRSLKESV
410 420 430 440 450
RENQHGSDKL AGEGVFVNKV PRQILPSPPN PALCVNTERP PSRPCIDIKF
460 470 480 490 500
RLLSRQEPRA GGVLSKSLMQ PMLTTGITPR SKAASRKVSE AISRKMSKAT
510 520 530 540 550
SRRISKATAL PISKSDILSE PGVVDSEGKV RFRVFQVKRP GEDRWSLVAY
560 570 580 590 600
KWLNHKRSPQ TAEDCVPLSC NEQCGGTSTA VCGASEKSVA ISHGTGASKQ
610 620 630 640 650
EGGLSSFVFP CASTVSLQIP GCMDSVQTPA VGDQGRCNTS CLPTVEAPQW
660 670 680 690 700
CSQGQVQQCS ASDNAELGLV ASGETAPGEP YQLSCYGIDA GQYCQFGDGT
710 720 730 740 750
PAEPVESWWT PQASAEDLQM VDTHYMDAEA WSQPNNGEGV WSDQFGIGDF
760 770 780 790 800
PQAFNSQEAR RSSTKLKQGN LPRASLAQTN PTSSAAVAVT SSMPVNQTES
810 820 830 840 850
RASRAHVRQR TSQQPPSRKA TRVSVPAEAK EGRKSVGEPR HSIGIGKRVS
860 870 880 890 900
STSASPGGAS TSSPARVISF APASYLKRAT SKRGTVAQEV SSSGAATAYT
910 920 930 940 950
LVADGGAQHS PQSMASFSRV EQKSPSANMA DVACSSWQCK PLSCCEKTES
960 970 980 990 1000
YVSAPPVSSC TWTRAGTTAN EQQVPSPAVS SEELDVLQQV PAHLRSSALL
1010 1020 1030 1040 1050
TGPEASQAVP PARTTTAPTE YQVPVGADAS DRQTKKEFSL KSWLVNSLLW
1060 1070 1080 1090 1100
SACRESDNAD TKKSEPSPEV SGLVKEEEEG ELPQISQEQA KQLKDEAEHA
1110 1120 1130 1140 1150
DDRVDVFPPH QISRDKQRKD GSISVFFREI KRRQDTRKLH SRRQDSRSAT
1160 1170 1180 1190 1200
AILERLASAS SVSAAAATKP EDELMSLLSA ATIYKDKPEP VFLFRVIQSQ
1210 1220 1230 1240 1250
QAKDREWRRL VAFRPPVHVR QPPAPYLPHT ESHMANSQGV HGDSASMRCV
1260 1270 1280 1290 1300
VPSACCRSAS VQSDDSIVTR KYEHRTSYVP LATRGKTLHV VTHHGVENAT
1310 1320 1330 1340 1350
QSVLRDEQKT QSERLPCVSS FAVKMAREAA ERMAVRQAIK EARGTGSSDR
1360 1370 1380 1390 1400
SGTELQTTEE TELVETDREE EVDDHEEPIQ EYEFQWEGTW RSIAGAAELF
1410 1420 1430 1440 1450
CCSDACASQT PITPSTRREA PMVMIEDSAD EEDKTDVEVV IEEGQEETED
1460 1470 1480 1490 1500
AVEEGGKQLH GAVEEGYKEA EQVIVEGEEG PVETLEQQGE QDDEVENADS
1510 1520 1530 1540 1550
WCMLSSAPES VQRGSCTSCC DGWRLTDNPP ATISPSCTSV RDSAPESRSE
1560 1570 1580 1590 1600
TVLSQGTAQY SSLSSSRSLQ PKCSYSCWGF PKYPFSSKES VASETGPRMP
1610 1620 1630 1640 1650
RESPLLSPPS AQEGDTAYED GFPVDDGLEE EQRQTPVYVI PPASASLGYQ
1660 1670 1680 1690 1700
ADGSFPYTTL WGYSYQQPPV AAIPVTIPSP ATTFPSTLSH SVMEGSGVGI
1710 1720 1730 1740 1750
PHQTSFSTSS PEFPVAFLPT TVVPFPAAPA PEPSHVRLSK IRLPPPPPPE
1760 1770 1780 1790 1800
MSESEGARLL VTSREEETQR GPPTWAVVPT PTHRVRIAVL PGRQPSSGGD
1810
DAVPCESWCG TQYCCE
Length:1,816
Mass (Da):194,254
Last modified:October 16, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2D0A6B759D236D65
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
KE138836 Genomic DNA Translation: EPT27070.1

NCBI Reference Sequences

More...
RefSeqi
XP_018636004.1, XM_018780110.1

Genome annotation databases

Ensembl protists genome annotation project

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EnsemblProtistsi
TGME49_225690-t26_1; TGME49_225690-t26_1-p1-CDS1; TGME49_225690

Database of genes from NCBI RefSeq genomes

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GeneIDi
7895081

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
tgo:TGME49_225690

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KE138836 Genomic DNA Translation: EPT27070.1
RefSeqiXP_018636004.1, XM_018780110.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

PTM databases

SwissPalmiS8G5U5

Genome annotation databases

EnsemblProtistsiTGME49_225690-t26_1; TGME49_225690-t26_1-p1-CDS1; TGME49_225690
GeneIDi7895081
KEGGitgo:TGME49_225690

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS8G5U5_TOXGM
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: S8G5U5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 16, 2013
Last sequence update: October 16, 2013
Last modified: July 31, 2019
This is version 14 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteomeImported
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Main funding by: National Institutes of Health

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