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Entry version 18 (31 Jul 2019)
Sequence version 1 (16 Oct 2013)
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Protein
Submitted name:

Uncharacterized protein

Gene

TGME49_212780

Organism
Toxoplasma gondii (strain ATCC 50611 / Me49)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:TGME49_212780Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiToxoplasma gondii (strain ATCC 50611 / Me49)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri508771 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaSarcocystidaeToxoplasma
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001529 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome V

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

PTM databases

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
S8F8U1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 33DisorderedSequence analysisAdd BLAST33
Regioni59 – 255DisorderedSequence analysisAdd BLAST197
Regioni280 – 398DisorderedSequence analysisAdd BLAST119
Regioni419 – 455DisorderedSequence analysisAdd BLAST37
Regioni478 – 498DisorderedSequence analysisAdd BLAST21
Regioni511 – 624DisorderedSequence analysisAdd BLAST114
Regioni687 – 853DisorderedSequence analysisAdd BLAST167
Regioni1136 – 1319DisorderedSequence analysisAdd BLAST184
Regioni1341 – 1627DisorderedSequence analysisAdd BLAST287
Regioni2009 – 2032DisorderedSequence analysisAdd BLAST24
Regioni2060 – 2097DisorderedSequence analysisAdd BLAST38
Regioni2126 – 2220DisorderedSequence analysisAdd BLAST95
Regioni2275 – 2334DisorderedSequence analysisAdd BLAST60

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili659 – 679Sequence analysisAdd BLAST21
Coiled coili1696 – 1726Sequence analysisAdd BLAST31
Coiled coili1731 – 1751Sequence analysisAdd BLAST21
Coiled coili1780 – 1842Sequence analysisAdd BLAST63
Coiled coili1932 – 1952Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi123 – 141PolyampholyteSequence analysisAdd BLAST19
Compositional biasi142 – 159PolarSequence analysisAdd BLAST18
Compositional biasi204 – 222PolarSequence analysisAdd BLAST19
Compositional biasi299 – 326PolyampholyteSequence analysisAdd BLAST28
Compositional biasi346 – 360AcidicSequence analysisAdd BLAST15
Compositional biasi440 – 455PolyampholyteSequence analysisAdd BLAST16
Compositional biasi520 – 534PolyampholyteSequence analysisAdd BLAST15
Compositional biasi575 – 624PolarSequence analysisAdd BLAST50
Compositional biasi704 – 719PolyampholyteSequence analysisAdd BLAST16
Compositional biasi773 – 791PolyampholyteSequence analysisAdd BLAST19
Compositional biasi792 – 806AcidicSequence analysisAdd BLAST15
Compositional biasi820 – 853PolyampholyteSequence analysisAdd BLAST34
Compositional biasi1136 – 1160PolarSequence analysisAdd BLAST25
Compositional biasi1167 – 1211PolarSequence analysisAdd BLAST45
Compositional biasi1251 – 1282PolyampholyteSequence analysisAdd BLAST32
Compositional biasi1283 – 1319PolarSequence analysisAdd BLAST37
Compositional biasi1388 – 1416PolyampholyteSequence analysisAdd BLAST29
Compositional biasi1417 – 1453PolarSequence analysisAdd BLAST37
Compositional biasi1454 – 1475PolyampholyteSequence analysisAdd BLAST22
Compositional biasi1491 – 1544PolyampholyteSequence analysisAdd BLAST54
Compositional biasi1605 – 1627PolyampholyteSequence analysisAdd BLAST23
Compositional biasi2015 – 2032PolyampholyteSequence analysisAdd BLAST18
Compositional biasi2072 – 2097PolyampholyteSequence analysisAdd BLAST26
Compositional biasi2126 – 2177PolyampholyteSequence analysisAdd BLAST52
Compositional biasi2185 – 2220PolarSequence analysisAdd BLAST36
Compositional biasi2288 – 2309PolarSequence analysisAdd BLAST22
Compositional biasi2310 – 2334PolyampholyteSequence analysisAdd BLAST25

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

S8F8U1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPQQRFSAAV GFGRRADPSS SSSDEENGRK LASLRTCFVN TRGVKSGEDD
60 70 80 90 100
VWVEVSRNPV QRGSARGSHS HSHALLEDGV NSAVPSRLNK GATRPRAGHA
110 120 130 140 150
YLDSGEYNQE SNRSEEGETE DEEGGQHAYY SWAREGESKT RGETQSLSQH
160 170 180 190 200
RSPALWQKNH GQDSARRLGH SGAGPEEECS ESDDDDRSSD DLPDRYLRQP
210 220 230 240 250
HPSAFQRSAA SYHGSGSRYS TGRGSRHGDA EASESGQGRS IVEPTVRRLQ
260 270 280 290 300
ESSAREVMAT VVEPRLKWKK SLEAFQSCLR MAPSDDEAVG YESDEEDERE
310 320 330 340 350
AESSRRPEVH LRGVASAEDT GHRKLRFTSS RSHGQAGLHT YPGQDELEDQ
360 370 380 390 400
EEEEGEDEEA DSDFAHRVAM ATGPRTGRRS QLPSERNKGD RCPMLGQCHD
410 420 430 440 450
EQMSRRLWDG EDEEAEAFYR GDTLSRQPPF ASRSVSLRSY PRHTPREDSE
460 470 480 490 500
DEEQQLAELK TYVNKKLSTL DRRYGAFRGG RRADESEDEE EARAVTESRK
510 520 530 540 550
AYRGTLLAAL ASGMGANDDK KSPRSPRFGS ADDTDWGEDT VSSPSFGAKS
560 570 580 590 600
LKSPAWKQTR EMVETGDKQR AALLSSGLRL TSQGDADTAS TLTSTPRIES
610 620 630 640 650
IRLSSPASSP SSFSASFPSS ENVVPKENVG SGVAGRVQQM MSVDEADGKG
660 670 680 690 700
EIGMRFMSVE EHDAKLKALQ DRYRAKYAEL KRTPILTENA EAEEEGDTAE
710 720 730 740 750
VQNLPGEIEH EPRGDAEEED VNQVVEEESP RAATDGEAEE EAGETCERED
760 770 780 790 800
GTDGEDGIGN GECGEQDTVA PEGQATEEEK EAEVHSEEAE GDVMELAEEE
810 820 830 840 850
QEEGVATLAP EEAAEECAEE HEAEAGNAAR EEDGGESPPG TGEAEKKEKS
860 870 880 890 900
NIKSQVVEAL QDVLLSVLRP PASLPSNSVS SLVPPFDNVP APDTPSACAT
910 920 930 940 950
PSAVAARSLL AALFGRTGSL SSSADSKEPL PLTEISPRGM RENEKILQRL
960 970 980 990 1000
ENASFASAES NLWTAAAAVV SGNPARALDT GDGIIRSVLP SPRDHPGGGS
1010 1020 1030 1040 1050
SETAWKASGA AVATDWTISL MRQGRDGEEL RRAVCPREFP LDAFQGVSAD
1060 1070 1080 1090 1100
GATSFDEASR EFPTYLASAF RPAGSTPAVA GSRFDGVDVA SFFVGRETEK
1110 1120 1130 1140 1150
RLPFDHMRVG EGEEGRDSIS HVPLFAGISG GFQVDNSVVT MPPSSLPCSP
1160 1170 1180 1190 1200
ERQQAPHQEE GSFSETDRSD PQIPSAVESS SACSPSSDSP HAFPVSSVTP
1210 1220 1230 1240 1250
KLRTLSETGS TVGRRGRGAA SVTSRGEKAK ETAPQTGGET PAASEVSRRT
1260 1270 1280 1290 1300
STDCTGRDKL NEVRRQLKER VGFQKSKSIG DQRPKSRSAS GVSSRRCVSR
1310 1320 1330 1340 1350
PTTPREIATS TQRQSQSFFS FEGPEVVRFP TVGELRRQLD ISQHTGTEGD
1360 1370 1380 1390 1400
RLNGKGGTGS AAILALLTGS SRLPKRELPV PPPGRPRDSG RSETETGKAT
1410 1420 1430 1440 1450
KKQSGLKTER PGRKSPDQSQ ELSSWIVSPP SRMASSVALC TTTAGGSSPR
1460 1470 1480 1490 1500
DRERTTSYGG DFENEEHDEE RCAASPHPRQ TTASGSGKRV AETEKTSEKK
1510 1520 1530 1540 1550
GKGEGKRETG ELGHGETKKA AVKAKEGRGG RKKDKKKAAE EAHQSEIEQP
1560 1570 1580 1590 1600
IFTPAPPSCG GRGIQGSSKK SKKEKTGWSG RRVSCSLESE SILEPQDSVE
1610 1620 1630 1640 1650
AASEPESEAT EKDLEAERHR QEMEAHKEEQ ALLLSATQKH VQEVHKELER
1660 1670 1680 1690 1700
LVRENATLQE EKQQQEIKVR QILKTASRTN LQLLALKAQQ PAWERLKKNE
1710 1720 1730 1740 1750
EQHHELEALE KELESLKRSV QERTSREHGT IVDLQARLAS TEQLLKERTE
1760 1770 1780 1790 1800
EVARKRVARE EEERIREIVC MQVEEWRLRC EAQAETLQRL TTRLSGAEQA
1810 1820 1830 1840 1850
KTQLESKLAE MLKLMERVKA ALVATRNEAE EHKKARESAE KELIWKHAKS
1860 1870 1880 1890 1900
VSCGVQTDTA RVKHSGDQAD LQPQKDVRTV AVQVGHPNEK SLQAQDSVRD
1910 1920 1930 1940 1950
QKLASALAKQ KQLTLQVRAE HKKRASAWSA EKAELQALVI SLQGRIAELE
1960 1970 1980 1990 2000
KIQKLTSGNK SSGPVNPGLG PFHANSYASG YALQVASLCS PGMAPGFVAS
2010 2020 2030 2040 2050
PFPLPPVSRV SQSVRDNATE KDAGRHGTRR KDLVAPVGAA PEFAEQEEQE
2060 2070 2080 2090 2100
LLDFVSDLIH SGDAGESPVV DRVPEAGKEG KEHEDHRAQQ PERRDDEHDV
2110 2120 2130 2140 2150
IAEDLRAMDE SVKVLEDQLE ERLRILGTHE DNLDAQGDNR QETETGEKKV
2160 2170 2180 2190 2200
EASGGAGRRR RGVSWTIDEK PSITKDGLRS EARSSPAVSP RTGVGTYQSR
2210 2220 2230 2240 2250
STESSASVFS RNSPSPSRLD SLLDSPVDAL YAEAALSGLE ETGLAELSFP
2260 2270 2280 2290 2300
GASAGASDSS GDFVQTRSIG QIFAEKTAVP SAHDAPQTAP SGGKNSYDSI
2310 2320 2330
SQLLTESRRE TRTSSAREKV QELRRQLREH GVLS
Length:2,334
Mass (Da):253,910
Last modified:October 16, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3473D2BB7A1382D0
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
KE138823 Genomic DNA Translation: EPT31177.1

NCBI Reference Sequences

More...
RefSeqi
XP_018637859.1, XM_018779575.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
TGME49_212780-t26_1; TGME49_212780-t26_1; TGME49_212780

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
7893609

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
tgo:TGME49_212780

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KE138823 Genomic DNA Translation: EPT31177.1
RefSeqiXP_018637859.1, XM_018779575.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

PTM databases

SwissPalmiS8F8U1

Genome annotation databases

EnsemblProtistsiTGME49_212780-t26_1; TGME49_212780-t26_1; TGME49_212780
GeneIDi7893609
KEGGitgo:TGME49_212780

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS8F8U1_TOXGM
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: S8F8U1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 16, 2013
Last sequence update: October 16, 2013
Last modified: July 31, 2019
This is version 18 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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