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Entry version 17 (31 Jul 2019)
Sequence version 1 (16 Oct 2013)
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Protein
Submitted name:

Uncharacterized protein

Gene

TGME49_227000

Organism
Toxoplasma gondii (strain ATCC 50611 / Me49)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:TGME49_227000Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiToxoplasma gondii (strain ATCC 50611 / Me49)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri508771 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaSarcocystidaeToxoplasma
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001529 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

PTM databases

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
S8F125

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 64DisorderedSequence analysisAdd BLAST64
Regioni80 – 166DisorderedSequence analysisAdd BLAST87
Regioni199 – 252DisorderedSequence analysisAdd BLAST54
Regioni278 – 309DisorderedSequence analysisAdd BLAST32
Regioni496 – 529DisorderedSequence analysisAdd BLAST34
Regioni636 – 659DisorderedSequence analysisAdd BLAST24
Regioni821 – 887DisorderedSequence analysisAdd BLAST67

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili325 – 359Sequence analysisAdd BLAST35
Coiled coili531 – 558Sequence analysisAdd BLAST28
Coiled coili783 – 810Sequence analysisAdd BLAST28
Coiled coili915 – 942Sequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi91 – 107Pro-richSequence analysisAdd BLAST17
Compositional biasi133 – 166PolarSequence analysisAdd BLAST34
Compositional biasi216 – 239PolarSequence analysisAdd BLAST24
Compositional biasi845 – 886PolyampholyteSequence analysisAdd BLAST42

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

S8F125-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASTRPGATL RNLLYPGTPR EVEGHTPPSV PPQAPLYPAG NIDSGSYHAA
60 70 80 90 100
SMSAPYSPRH VSKHPTLPAR AVRFASQRFY RNYSPPPSSQ TETPADTPEP
110 120 130 140 150
PSPLLAPERL FDFPGPATSL SRQFARAGQS LRAPVTGPTS KERSISLSRA
160 170 180 190 200
PHRSLSSLSL SSPRLSQDKY ATSHALEGRS VGRSDVVRGV VPVGMAGMSS
210 220 230 240 250
FGVSGPGEKQ HGSSPRAGSR GATMSSFTSP AQSAPEAAVG SKEQQGVVDT
260 270 280 290 300
PGNESAFAFS RAASRGFFVS DYENQQSSSD AFQCGDVPRT GAQHGPSEAS
310 320 330 340 350
GLYTPQDRLP QEAQIRGSQL SSGRTETLQE RQERLQREMD ALRQRQQLVT
360 370 380 390 400
QQARQLYQQK MARPWLVPCN VSPDSTRLAT LAIIPSKESR KGSCERSGSC
410 420 430 440 450
PIFSRCARSG RRRSSGSRVR RIGVYVRPTA PSGQTVPPPA PGASFETNAA
460 470 480 490 500
TVPGWFWENP GLLQCVAPVE VSCSDGKGGG VRSHPLVLKV DVVPSQTGSS
510 520 530 540 550
LGKKEEDWKK SQASLVSSAS ASETPKTDPR IVELAKENDT LRQDNALLKA
560 570 580 590 600
QLERAHAEGV RRRLTNIDLS RRSQVDVYGE DGLLWGQEVE NEKLRRQIAE
610 620 630 640 650
LGAALYAAAE DGDFRLAAEA LTQQLTDAHQ EIATLRKSMR SDSSGRQGPR
660 670 680 690 700
CRDTSDDATL GANDISVREA AVDSLISQGK RVTTLGRENV WKALSSMKDL
710 720 730 740 750
VDQVFDRMTR LLTSTCTMKE KVQYLKGLHV LVVSSLDETL DAYEELAATC
760 770 780 790 800
NKFDQIRAVV FDPKRNSPYC PCRPRRQVLE DDLKHLCIQN KGATEKLRQL
810 820 830 840 850
RARIVKLEME NLKFYVKHPD EPVRSSEARP VSPLAASLEV KATETERLSS
860 870 880 890 900
PKKDKKEKRD RRDISSKDDS ASATTAADDD SDRSGSVMRR AVAASRKKVW
910 920 930 940 950
RKRQEVFPVR EDFSTYQLAS TIKRLQDEID RLKDDRQFDR TKAAEREQHL
960 970 980 990 1000
VSRVFNRNQI LVDKLAEQDR LLARLMQMIE DRDCMHALAG PTSPTQLAQR
1010 1020 1030 1040 1050
QALHEDLEES RTLIRQSSVA LREGQTPEPQ AFDNLITRLR TLKRDGLRDV
1060 1070 1080
TPEEQELLDM INRQASQLRK IHQTVTELAD HT
Length:1,082
Mass (Da):119,494
Last modified:October 16, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2B1A37560BB33384
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
KE138836 Genomic DNA Translation: EPT27198.1

NCBI Reference Sequences

More...
RefSeqi
XP_018636054.1, XM_018780159.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
TGME49_227000-t26_1; TGME49_227000-t26_1; TGME49_227000

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
7897588

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
tgo:TGME49_227000

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KE138836 Genomic DNA Translation: EPT27198.1
RefSeqiXP_018636054.1, XM_018780159.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

PTM databases

SwissPalmiS8F125

Genome annotation databases

EnsemblProtistsiTGME49_227000-t26_1; TGME49_227000-t26_1; TGME49_227000
GeneIDi7897588
KEGGitgo:TGME49_227000

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS8F125_TOXGM
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: S8F125
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 16, 2013
Last sequence update: October 16, 2013
Last modified: July 31, 2019
This is version 17 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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Main funding by: National Institutes of Health

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