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Entry version 27 (02 Jun 2021)
Sequence version 1 (16 Oct 2013)
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Protein
Submitted name:

Cyclic nucleotide-binding domain-containing protein

Gene

TGME49_219070

Organism
Toxoplasma gondii (strain ATCC 50611 / Me49)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mg2+ARBA annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransferaseImported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Cyclic nucleotide-binding domain-containing proteinImported (EC:2.7.11.12Imported)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:TGME49_219070Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiToxoplasma gondii (strain ATCC 50611 / Me49)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri508771 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaSarAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaSarcocystidaeToxoplasma
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001529 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome XII

Organism-specific databases

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
ToxoDB:TGME49_219070

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

PTM databases

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
S8EN17

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1038 – 1073EF-handInterPro annotationAdd BLAST36
Domaini1268 – 1356Cyclic nucleotide-bindingInterPro annotationAdd BLAST89
Domaini1381 – 1489Cyclic nucleotide-bindingInterPro annotationAdd BLAST109
Domaini1580 – 1684Cyclic nucleotide-bindingInterPro annotationAdd BLAST105
Domaini1738 – 1837Cyclic nucleotide-bindingInterPro annotationAdd BLAST100
Domaini2105 – 2140EF-handInterPro annotationAdd BLAST36
Domaini2223 – 2258EF-handInterPro annotationAdd BLAST36
Domaini2339 – 2449Cyclic nucleotide-bindingInterPro annotationAdd BLAST111
Domaini2464 – 2585Cyclic nucleotide-bindingInterPro annotationAdd BLAST122

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni514 – 542DisorderedSequence analysisAdd BLAST29
Regioni592 – 624DisorderedSequence analysisAdd BLAST33
Regioni669 – 691DisorderedSequence analysisAdd BLAST23
Regioni706 – 970DisorderedSequence analysisAdd BLAST265
Regioni1001 – 1026DisorderedSequence analysisAdd BLAST26
Regioni1507 – 1551DisorderedSequence analysisAdd BLAST45
Regioni1875 – 2088DisorderedSequence analysisAdd BLAST214
Regioni2586 – 2720DisorderedSequence analysisAdd BLAST135

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili28 – 62Sequence analysisAdd BLAST35
Coiled coili204 – 257Sequence analysisAdd BLAST54
Coiled coili284 – 304Sequence analysisAdd BLAST21
Coiled coili319 – 339Sequence analysisAdd BLAST21
Coiled coili384 – 418Sequence analysisAdd BLAST35

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi514 – 533Basic and acidic residuesSequence analysisAdd BLAST20
Compositional biasi706 – 933Basic and acidic residuesSequence analysisAdd BLAST228
Compositional biasi1507 – 1527Basic and acidic residuesSequence analysisAdd BLAST21
Compositional biasi1881 – 1962Basic and acidic residuesSequence analysisAdd BLAST82
Compositional biasi1970 – 2003Basic and acidic residuesSequence analysisAdd BLAST34
Compositional biasi2033 – 2081Basic and acidic residuesSequence analysisAdd BLAST49
Compositional biasi2643 – 2668Basic and acidic residuesSequence analysisAdd BLAST26
Compositional biasi2685 – 2699Polar residuesSequence analysisAdd BLAST15

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00038, CAP_ED, 5 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.10, 6 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR018490, cNMP-bd-like
IPR018488, cNMP-bd_CS
IPR000595, cNMP-bd_dom
IPR011992, EF-hand-dom_pair
IPR002048, EF_hand_dom
IPR014710, RmlC-like_jellyroll

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00027, cNMP_binding, 5 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00100, cNMP, 5 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47473, SSF47473, 1 hit
SSF51206, SSF51206, 6 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00888, CNMP_BINDING_1, 1 hit
PS00889, CNMP_BINDING_2, 2 hits
PS50042, CNMP_BINDING_3, 6 hits
PS50222, EF_HAND_2, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

S8EN17-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
METRAMLGAP WSAAEGGDGV ADPDRLYTRS LREDLEEARD KLLKLKKMNE
60 70 80 90 100
LLEGENQDLR RRLLSQLVNC PDAAETRELA RRYGPELAHA FSSLSDENKY
110 120 130 140 150
LKVKLQSSQR AEVRAEIRAE QLANALRSDE EKRYAFGLAR DAARGSISSK
160 170 180 190 200
VAMLEAGCLG SSARGDVGDS PVFRGEDVPG PVAVLRDNKH LRLRADANEH
210 220 230 240 250
CLCTEKLQEL MDSLDDNLKS YERNVWQLQV NVLEDERTEL QMKVANLSER
260 270 280 290 300
LTEIQSKIMN DPFLSAKYAA AGTPGAVPNA QTQLREASAR LALAESVNAE
310 320 330 340 350
LERRLAFERS ISRSWQTNLR AMQRELREHL ASLALASRKS GMSCDLFRGG
360 370 380 390 400
ILQAAEAAAR RDLAGVPGCE RESLRLLRQA ADRIDSDAKR LEVYSSRIAE
410 420 430 440 450
LEREVKDLRF SNTRLAESTT RVCARSVDPV ESLSVFPPVC DVCPRVSSVD
460 470 480 490 500
PGDALRSGLL FARQMLADRL VCKDMLHEID NRRKELRERE AALGFSHAAL
510 520 530 540 550
NCLRAVPADV YGMKRRKRQE ENRENHRRES ESESLDDDVE EAETVRMRVS
560 570 580 590 600
ESAWSQDRDR LLVRQVELLR RLAGGEAKLR FPRTGAIEEA ELGEEREKRR
610 620 630 640 650
KKKKKRLEGY KEKGREDASY RLSPEVEALM QSTEASLRDE VADIKEKAEA
660 670 680 690 700
ETERKAEKER LMWEVKKARE QASREMRKQM EEMRKQMEKE KRELVRRLEE
710 720 730 740 750
EKLRHREALE AEEKREKERR RERQKAEEAF WREREERRKK AEEDEERRRR
760 770 780 790 800
EREEEDARLR AERERRFQEE EEEREQRRQQ RIREEDEERR MREERRRREE
810 820 830 840 850
AEEEERRQRR KEEEERDAER RRHMLEKEEE DRRRKKEIEE ADKEARRRKQ
860 870 880 890 900
AVEEEERRRK KRAEEEEEEE RRRKKRAEEE EEEERRRKKR AEEEEEEERR
910 920 930 940 950
RKKRAEEEEE DRQRRLREAN ESAQKEEDSV KNETASSPPH TDNISTTRQE
960 970 980 990 1000
EPGREATADA SDGQPPRSLG RLAKRNASLA TSIAPVKMAE VADLAENPAV
1010 1020 1030 1040 1050
AASTSSGAGE GDLSDSETES VTNASYSPRT ALKHKILDKY NSLANAFKYM
1060 1070 1080 1090 1100
DTRRVGSVTL HQFADFVDES GLDYPFSTVH SLYCQLSQPA DTLTEGLMYR
1110 1120 1130 1140 1150
NMDGDATLVQ LGRRLEDIYG NMGVPFEAEG IGPTGRVTRE AFYRVCTKAG
1160 1170 1180 1190 1200
LTAENSHALW NSIDLLGSGH LQMESLLLLL EDNVELEEVK RVEEEIANME
1210 1220 1230 1240 1250
GGFMSFFGQT GPVPSPQPKH KRHESCGRPL ALTRKLSLGF TEAEAAIDNV
1260 1270 1280 1290 1300
LEADSHWDVL FPLTRLAMIK QMQKTVYQPG ERIQEAQDNA CPLYIVMTGS
1310 1320 1330 1340 1350
IQLLSPGLLM ETVAEEKSAP QLLFSEEMLE DKPNPFAVKA LTATKVFAYS
1360 1370 1380 1390 1400
REDFVRSVKH EQIKRTRDVA TNMALIKIVP VLSKLTEVQA RRLARTFGEE
1410 1420 1430 1440 1450
TFEDGEAIFK EFDEPDNFYL VKKGEAAVVK YKKDPTTKEM EEVVFRIYQP
1460 1470 1480 1490 1500
GEYFGEISIL RDQTRTATVK ARGICTVLSL PKEDFNSQLR RFEAAFIGRA
1510 1520 1530 1540 1550
GRVYTAQGHV DKDKKPKKEK ETLPTSVEEP EEPTDGASIE ETSADSQSRE
1560 1570 1580 1590 1600
GLGQTIEDML ATEQTKLRDE CMLLLEGVPV LKELSLERRK EIVKAMSLEC
1610 1620 1630 1640 1650
FYPNTPIILQ GEESQNFYVL KTGTVAAELY VGPGKPFRKI KEYNSTCYFG
1660 1670 1680 1690 1700
EMSIIKNEPR GCYITAKSPV QLYSLTGEKF KELLEDCYPA FQEYAQAQYE
1710 1720 1730 1740 1750
QETLKRQASS QLVSSEAVRE EPTADYGEIM NLLVQVPVIN MLDEDALQQL
1760 1770 1780 1790 1800
TRAFKVECYQ EREVIIHEGT PAEHFFIIFS GDVSVQKIVD GAPVEIVVLH
1810 1820 1830 1840 1850
AGEYLGEIAF LNEQPRTASC VAKSDVKLLS LTRSDFQVHL GALQDAFLNQ
1860 1870 1880 1890 1900
AESKYAASKD EAIPDWLVEA GEQGALYDPS GSKKTEDEDE EPDGAFRGTV
1910 1920 1930 1940 1950
DIDKEKEMYN KKRGRKDSDT SRKKSDASAD KTGEAKASDA HRKKSGETPP
1960 1970 1980 1990 2000
GDGEEEAGKP GNDEVAEVAA DTNTVEKKKK KAKEKEKHGG ESEETGGETK
2010 2020 2030 2040 2050
KKGKQSQAKR RMSLAGGAAL LAAAAAAKAA EGEPSPNEKE QEEKEETKAG
2060 2070 2080 2090 2100
EMEEKQDKEE TAEKEKKKEK KKKKKKDEDE DAEDKAAEEQ RIDEFRDLVR
2110 2120 2130 2140 2150
GTLKNKYGSI AQAFQQIDGN NSEIVDFDEF AAFVKDLRVQ SLKKKDIQVL
2160 2170 2180 2190 2200
FDDLCQPLKG TLTVANLYRN IDKKDQLSKA EINLRWVEIF GGSRKAFKAV
2210 2220 2230 2240 2250
ANLGGGDECT EENFINVAAA AGVSEENAKS IWTELDKAQT GQMHTKVICS
2260 2270 2280 2290 2300
YMAGELTAEE AAAKEEELAS LGTRLWNFFG GSASDDESAS ASSPTSQGDE
2310 2320 2330 2340 2350
QKIQEALKWE DMAIVQRDDH RTYPTCTKRL VDVLEKKEGF MNLQLLQLRY
2360 2370 2380 2390 2400
VASTMRRECL AKGVRVMEAG DEACMVFCAW GEFKILQAGL FGESEVGVVC
2410 2420 2430 2440 2450
PDECFGLSEL INDSPLTASL VTEVDNSVLW VLERDTYNDL IRDMLEARRA
2460 2470 2480 2490 2500
VVPVIENFLK SVPIVKDMSE TEIQNVARAC KIETFSPHQT VFRAGMAGDM
2510 2520 2530 2540 2550
FCFIFKGEIT MLKPMGAGQE PIELGRLQAG VYFGEMAVIK NQRRTASIIA
2560 2570 2580 2590 2600
ATDLTLFCLD KGSFERVLGR VKGKMIERAE SLYKRQDVAT TDPKEGEEGN
2610 2620 2630 2640 2650
AAASSASAAG AAESFGPGDH FEKKRTRKSS LALLQYTKIR EAGPAEGESE
2660 2670 2680 2690 2700
KKSSEEDEER EARWAMAQDP EIIHRPPPLS AAPKKSALRT TSSKSVGIKN
2710 2720
SVFFDEETLL PSPPSSDEGE
Length:2,720
Mass (Da):307,967
Last modified:October 16, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7B891EAD6A15D606
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
KE138840 Genomic DNA Translation: EPT24641.1

NCBI Reference Sequences

More...
RefSeqi
XP_018634819.1, XM_018779826.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
TGME49_219070-t26_1; TGME49_219070-t26_1; TGME49_219070

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
7893556

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
tgo:TGME49_219070

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KE138840 Genomic DNA Translation: EPT24641.1
RefSeqiXP_018634819.1, XM_018779826.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

PTM databases

SwissPalmiS8EN17

Genome annotation databases

EnsemblProtistsiTGME49_219070-t26_1; TGME49_219070-t26_1; TGME49_219070
GeneIDi7893556
KEGGitgo:TGME49_219070

Organism-specific databases

VEuPathDBiToxoDB:TGME49_219070

Family and domain databases

CDDicd00038, CAP_ED, 5 hits
Gene3Di2.60.120.10, 6 hits
InterProiView protein in InterPro
IPR018490, cNMP-bd-like
IPR018488, cNMP-bd_CS
IPR000595, cNMP-bd_dom
IPR011992, EF-hand-dom_pair
IPR002048, EF_hand_dom
IPR014710, RmlC-like_jellyroll
PfamiView protein in Pfam
PF00027, cNMP_binding, 5 hits
SMARTiView protein in SMART
SM00100, cNMP, 5 hits
SUPFAMiSSF47473, SSF47473, 1 hit
SSF51206, SSF51206, 6 hits
PROSITEiView protein in PROSITE
PS00888, CNMP_BINDING_1, 1 hit
PS00889, CNMP_BINDING_2, 2 hits
PS50042, CNMP_BINDING_3, 6 hits
PS50222, EF_HAND_2, 3 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS8EN17_TOXGM
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: S8EN17
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 16, 2013
Last sequence update: October 16, 2013
Last modified: June 2, 2021
This is version 27 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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