Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 27 (31 Jul 2019)
Sequence version 1 (16 Oct 2013)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein
Submitted name:

Chromodomain-helicase-DNA-binding protein 1

Gene

D623_10033904

Organism
Myotis brandtii (Brandt's bat)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-bindingImported, HelicaseImported, Hydrolase
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Chromodomain-helicase-DNA-binding protein 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:D623_10033904Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMyotis brandtii (Brandt's bat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri109478 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaChiropteraMicrochiropteraVespertilionidaeMyotis

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
109478.XP_005871594.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini348 – 440ChromoInterPro annotationAdd BLAST93
Domaini465 – 528ChromoInterPro annotationAdd BLAST64
Domaini569 – 739Helicase ATP-bindingInterPro annotationAdd BLAST171
Domaini868 – 1019Helicase C-terminalInterPro annotationAdd BLAST152

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 64DisorderedSequence analysisAdd BLAST64
Regioni89 – 328DisorderedSequence analysisAdd BLAST240
Regioni1156 – 1197DisorderedSequence analysisAdd BLAST42
Regioni1397 – 1573DisorderedSequence analysisAdd BLAST177
Regioni1690 – 1878DisorderedSequence analysisAdd BLAST189

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi16 – 64PolyampholyteSequence analysisAdd BLAST49
Compositional biasi93 – 145PolarSequence analysisAdd BLAST53
Compositional biasi164 – 202PolarSequence analysisAdd BLAST39
Compositional biasi210 – 227PolyampholyteSequence analysisAdd BLAST18
Compositional biasi268 – 283BasicSequence analysisAdd BLAST16
Compositional biasi302 – 328PolyampholyteSequence analysisAdd BLAST27
Compositional biasi1163 – 1184PolyampholyteSequence analysisAdd BLAST22
Compositional biasi1406 – 1420BasicSequence analysisAdd BLAST15
Compositional biasi1421 – 1554PolyampholyteSequence analysisAdd BLAST134
Compositional biasi1693 – 1834PolyampholyteSequence analysisAdd BLAST142
Compositional biasi1835 – 1856PolarSequence analysisAdd BLAST22
Compositional biasi1859 – 1878PolyampholyteSequence analysisAdd BLAST20

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.10810, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR040793 CDH1_2_SANT_HL1
IPR016197 Chromo-like_dom_sf
IPR000953 Chromo/chromo_shadow_dom
IPR023780 Chromo_domain
IPR023779 Chromodomain_CS
IPR025260 DUF4208
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR000330 SNF2_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF18375 CDH1_2_SANT_HL1, 1 hit
PF00385 Chromo, 2 hits
PF13907 DUF4208, 1 hit
PF00271 Helicase_C, 1 hit
PF00176 SNF2_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00298 CHROMO, 2 hits
SM00487 DEXDc, 1 hit
SM01176 DUF4208, 1 hit
SM00490 HELICc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 2 hits
SSF54160 SSF54160, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00598 CHROMO_1, 2 hits
PS50013 CHROMO_2, 2 hits
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

S7PRA9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLDRLGQGYG RPGLRDLREG SQKEDLEKEG EGGRKLQCTK KAILRGESKE
60 70 80 90 100
RKEERTFSTE RDFSGERQFA RVSRFLSKTA VTVELFGWLD QSDDDSGSAS
110 120 130 140 150
GSGSGSSSGS SSDGSSSQSG SSDSDSGSES GSQSESESDT SGENKVQAKP
160 170 180 190 200
PKVDGAEFWK SSPSILAVQR SAMLKKQQQQ QQHQQQQQQQ QQVSSNSGSE
210 220 230 240 250
EDSSSSEDSD DTSSEVKRKK HKDEDWQMSA SGSPSQSGSD SESEEEGDKS
260 270 280 290 300
SCDETESDYE PKNKVKSRKP QNRSKSKNGK KILGQKKRQI DSSEEDDDED
310 320 330 340 350
YDNDKRSSRR QATVNVSYKE DEEMKTDSDD LLEVCGEDVP QPEEEEFETI
360 370 380 390 400
ERFMDCRIGR KGATGATTTI YAVEADGDPN AGFEKNKEPG EIQYLIKWKG
410 420 430 440 450
WSHIHNTWET EETLKQQNVR GMKKLDNYKK KDQETKRWLK NASPEDVEYY
460 470 480 490 500
NCQQELTDDL HKQYQIVERI IAHSNQKSAA GYPDYYCKWQ GLPYSECSWE
510 520 530 540 550
DGALISKKFQ ACIDEYFSRN QSKTTPFKDC KVLKQRPRFV ALKKQPSYIG
560 570 580 590 600
GHEGLELRDY QLNGLNWLAH SWCKGNSCIL ADEMGLGKTI QTISFLNYLF
610 620 630 640 650
NEHQLYGPFL LVVPLSTLTS WQREIQTWAS QMNAVVYLGD INSRNMIRTH
660 670 680 690 700
EWMHPQTKRL KFNILLTTYE ILLKDKAFLG GLNWAFIGVD EAHRLKNDDS
710 720 730 740 750
LLYKTLIDFK SNHRLLITGT PLQNSLKELW SLLHFIMPEK FSSWEDFEEE
760 770 780 790 800
HGKGREYGYA SLHKELEPFL LRRVKKDVEK SLPAKVEQIL RMEMSALQKQ
810 820 830 840 850
YYKWILTRNY KALSKGSKGS TSGFLNIMME LKKCCNHCYL IKPPDNNEFY
860 870 880 890 900
NKQEALQHLI RSSGKLILLD KLLIRLRERG NRVLIFSQMV RMLDILAEYL
910 920 930 940 950
KYRQFPFQRL DGSIKGELRK QALDHFNAEG SEDFCFLLST RAGGLGINLA
960 970 980 990 1000
SADTVVIFDS DWNPQNDLQA QARAHRIGQK KQVNIYRLVT KGSVEEDILE
1010 1020 1030 1040 1050
RAKKKMVLDH LVIQRMDTTG KTVLHTGSAP SSSTPFNKEE LSAILKFGAE
1060 1070 1080 1090 1100
ELFKEPEGEE QEPQEMDIDE ILKRAETHEN EPGPLTVGDE LLSQFKVANF
1110 1120 1130 1140 1150
SNMDEDDIEL EPERSSKNWE EIIPEDQRRR LEEEERQKEL EEIYMLPRMR
1160 1170 1180 1190 1200
NCAKQISFNG SEGRRSRSRR YSGSDSDSIS ERKRPKKRGR PRTIPRENIK
1210 1220 1230 1240 1250
GFSDAEIRRF IKSYKKFGGP LERLDAIARD AELVDKSETD LRRLGELVHN
1260 1270 1280 1290 1300
GCIKALKDNS SGTERTGGRL GKVKGPTFRI SGVQVNAKLV ISHEEELIPL
1310 1320 1330 1340 1350
HKSIPSDPEE RKQYTIPCHT KAAHFDIDWG KEDDSNLLIG IYEYGYGSWE
1360 1370 1380 1390 1400
MIKMDPDLSL THKILPDDPD KKPQAKQLQT RADYLIKLLS RDLAKKEAQR
1410 1420 1430 1440 1450
LSGAGGSKRR KARAKKNKSM KSTKVKEEVK SDSSPLLSEK SDEDDKDKVT
1460 1470 1480 1490 1500
SLKHPNKKIK TERDSEEKPE PDVFIKKEPE EKRESKEKEN KRELKREIEE
1510 1520 1530 1540 1550
KENKKDIKQK DFKEKREKKV KEAIEAMQKE KDIKEEKLSE SKSDSKERSK
1560 1570 1580 1590 1600
KSSVSDPLVH ITASGEPVPI SEESEELDQK TFSICKERMR PVKAALKQLD
1610 1620 1630 1640 1650
RPEKGLSERE QLEHTRQCLI KIGDHITECL KEYTNPEQIK QWRKNLWIFV
1660 1670 1680 1690 1700
SKFTEFDARK LHKLYKHAIK KRQESQQNND QNINMNIQVI RNPDVERLKE
1710 1720 1730 1740 1750
NTNHDDSSRD SYSSDRHLSQ YHDHHKDRHQ GDSYKKSDSR KRPYSSFSNG
1760 1770 1780 1790 1800
KDHRDWDHYK QDSRYYNDRE KHRKLDDHRS RDHRSNLEGS LKDRSHSDHR
1810 1820 1830 1840 1850
SHSDHRLHSD HRSSSEYTHH KSSRDYRYHS DWQMDHRASS SGPRSPLDQR
1860 1870
SPYGSRSPFE HSIEHKSTPE HTWSNRKT
Length:1,878
Mass (Da):217,053
Last modified:October 16, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCA3C23D012815867
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
KE163134 Genomic DNA Translation: EPQ10997.1

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KE163134 Genomic DNA Translation: EPQ10997.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi109478.XP_005871594.1

Family and domain databases

Gene3Di3.40.50.10810, 1 hit
InterProiView protein in InterPro
IPR040793 CDH1_2_SANT_HL1
IPR016197 Chromo-like_dom_sf
IPR000953 Chromo/chromo_shadow_dom
IPR023780 Chromo_domain
IPR023779 Chromodomain_CS
IPR025260 DUF4208
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR000330 SNF2_N
PfamiView protein in Pfam
PF18375 CDH1_2_SANT_HL1, 1 hit
PF00385 Chromo, 2 hits
PF13907 DUF4208, 1 hit
PF00271 Helicase_C, 1 hit
PF00176 SNF2_N, 1 hit
SMARTiView protein in SMART
SM00298 CHROMO, 2 hits
SM00487 DEXDc, 1 hit
SM01176 DUF4208, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
SSF54160 SSF54160, 2 hits
PROSITEiView protein in PROSITE
PS00598 CHROMO_1, 2 hits
PS50013 CHROMO_2, 2 hits
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS7PRA9_MYOBR
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: S7PRA9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 16, 2013
Last sequence update: October 16, 2013
Last modified: July 31, 2019
This is version 27 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again