We will be switching to the new UniProt website soon. Please explore and share your feedback.
Take me to the new website.
UniProtKB - S6B677 (S6B677_SULDS)
Protein
Protein translocase subunit SecD
Gene
secD
Organism
Sulfuricella denitrificans (strain DSM 22764 / NBRC 105220 / skB26)
Status
Functioni
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
UniRule annotationCaution
Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation
GO - Molecular functioni
- protein-transporting ATPase activity Source: InterPro
GO - Biological processi
- intracellular protein transmembrane transport Source: UniProtKB-UniRule
- protein targeting Source: UniProtKB-UniRule
- protein transport by the Sec complex Source: UniProtKB-UniRule
Keywordsi
Biological process | Protein transport, TranslocationUniRule annotationARBA annotation, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Protein translocase subunit SecDUniRule annotation |
Gene namesi | Name:secDUniRule annotation ORF Names:SCD_n02208Imported |
Organismi | Sulfuricella denitrificans (strain DSM 22764 / NBRC 105220 / skB26)Imported |
Taxonomic identifieri | 1163617 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Betaproteobacteria › Nitrosomonadales › Sulfuricellaceae › Sulfuricella › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 448 – 465 | HelicalUniRule annotationAdd BLAST | 18 | |
Transmembranei | 472 – 491 | HelicalUniRule annotationAdd BLAST | 20 | |
Transmembranei | 497 – 517 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 538 – 560 | HelicalUniRule annotationAdd BLAST | 23 | |
Transmembranei | 566 – 590 | HelicalUniRule annotationAdd BLAST | 25 |
Keywords - Cellular componenti
Cell membraneUniRule annotationARBA annotation, MembraneInteractioni
Subunit structurei
Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
UniRule annotationProtein-protein interaction databases
STRINGi | 1163617.SCD_n02208 |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 103 | SecD-TM1InterPro annotationAdd BLAST | 103 |
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixUniRule annotationARBA annotationPhylogenomic databases
eggNOGi | COG0342, Bacteria |
HOGENOMi | CLU_007894_4_3_4 |
OrthoDBi | 121331at2 |
Family and domain databases
HAMAPi | MF_01463_B, SecD_B, 1 hit |
InterProi | View protein in InterPro IPR005791, SecD IPR027398, SecD-TM IPR022813, SecD/SecF_arch_bac IPR022645, SecD/SecF_bac IPR022646, SecD/SecF_CS |
PANTHERi | PTHR30081, PTHR30081, 1 hit |
Pfami | View protein in Pfam PF07549, Sec_GG, 1 hit PF13721, SecD-TM1, 1 hit PF02355, SecD_SecF, 1 hit |
TIGRFAMsi | TIGR00916, 2A0604s01, 1 hit TIGR01129, secD, 1 hit |
i Sequence
Sequence statusi: Complete.
S6B677-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNRYPLWKYI LIAAAMLFGL IYTLPNFFGE SPAVQVSPLR GMTKVDQGLM
60 70 80 90 100
KQVEEVLKQN NLAFQGIAFD SSGVKVRFAD ADTQIKAKDI LQSNLGENFV
110 120 130 140 150
VALNLLSSSP KWLSSMGALP MYLGLDLRGG VHFLLQVDMK GAITKALDRY
160 170 180 190 200
NGDIRTSLRE KRIAYAGISR QDQAVEIKFR DAESRQKAMD ELQKTSPDLL
210 220 230 240 250
LKEVDAGAEF KLVATLKLGA QKRIQEFALQ QNITTLRNRI NELGVAEPII
260 270 280 290 300
QQQGIDRVVV QLPGVQDTAK AKDILGRTAT LEIRMVDEEH DVTAAVQSGQ
310 320 330 340 350
IPFGSELYTE RKGLPLLVKK GVVLTGDYIS DAQPGFEGQS GEPAVHINLD
360 370 380 390 400
GRGARIFKQL TRDNVGKRMA ILLIEKGKGE VITAPVIREE IGGGRVQISG
410 420 430 440 450
RMTTMEASDV SLLLRAGALA APMEIIEERT VGPSMGAENI AKGFNSNIYG
460 470 480 490 500
FVAIAAFMMF YYRFFGVVST TALAVNVLLL VAILSLLQAT LTLPGMAGIA
510 520 530 540 550
LTVGMAIDSN VLINERIREE IRNGLSPQAA IHSGYERAFA TILDSNITTL
560 570 580 590 600
IAGVALFWLG SGPVRGFAVV LCLGILTSMF SAVVVSRGMV NLTYGRKARL
EKVSI
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP013066 Genomic DNA Translation: BAN36017.1 |
RefSeqi | WP_009205213.1, NC_022357.1 |
Genome annotation databases
EnsemblBacteriai | BAN36017; BAN36017; SCD_n02208 |
KEGGi | sdr:SCD_n02208 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP013066 Genomic DNA Translation: BAN36017.1 |
RefSeqi | WP_009205213.1, NC_022357.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 1163617.SCD_n02208 |
Genome annotation databases
EnsemblBacteriai | BAN36017; BAN36017; SCD_n02208 |
KEGGi | sdr:SCD_n02208 |
Phylogenomic databases
eggNOGi | COG0342, Bacteria |
HOGENOMi | CLU_007894_4_3_4 |
OrthoDBi | 121331at2 |
Family and domain databases
HAMAPi | MF_01463_B, SecD_B, 1 hit |
InterProi | View protein in InterPro IPR005791, SecD IPR027398, SecD-TM IPR022813, SecD/SecF_arch_bac IPR022645, SecD/SecF_bac IPR022646, SecD/SecF_CS |
PANTHERi | PTHR30081, PTHR30081, 1 hit |
Pfami | View protein in Pfam PF07549, Sec_GG, 1 hit PF13721, SecD-TM1, 1 hit PF02355, SecD_SecF, 1 hit |
TIGRFAMsi | TIGR00916, 2A0604s01, 1 hit TIGR01129, secD, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | S6B677_SULDS | |
Accessioni | S6B677Primary (citable) accession number: S6B677 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 16, 2013 |
Last sequence update: | October 16, 2013 | |
Last modified: | September 29, 2021 | |
This is version 41 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |