UniProtKB - S4R3S7 (S4R3S7_HUMAN)
Protein
Submitted name:
Acetyl-CoA carboxylase 2
Gene
ACACB
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
Keywordsi
Ligand | ATP-bindingARBA annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Submitted name: Acetyl-CoA carboxylase 2Imported |
Gene namesi | Name:ACACBImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000076555.15 |
HGNCi | HGNC:85, ACACB |
Expressioni
Gene expression databases
Bgeei | ENSG00000076555, Expressed in parietal pleura and 237 other tissues |
ExpressionAtlasi | S4R3S7, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 57 – 155 | Biotin carboxylationInterPro annotationAdd BLAST | 99 |
Phylogenomic databases
GeneTreei | ENSGT00940000155049 |
HOGENOMi | CLU_077570_1_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR005481, BC-like_N IPR011764, Biotin_carboxylation_dom IPR016185, PreATP-grasp_dom_sf |
Pfami | View protein in Pfam PF00289, Biotin_carb_N, 1 hit |
SUPFAMi | SSF52440, SSF52440, 1 hit |
PROSITEi | View protein in PROSITE PS50979, BC, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All
S4R3S7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSPAKCKICF PDREVKPSMS GLHLVKRGRE HKKLDLHRDF TVASPAEFVT
60 70 80 90 100
RFGGDRVIEK VLIANNGIAA VKCMRSIRRW AYEMFRNERA IRFVVMVTPE
110 120 130 140 150
DLKANAEYIK MADHYVPVPG GPNNNNYANV ELIVDIAKRI PVQAVWAGWG
HASEN
Computationally mapped potential isoform sequencesi
There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketO00763 | ACACB_HUMAN | Acetyl-CoA carboxylase 2 | ACACB ACC2, ACCB | 2,458 | Annotation score: | ||
F8W8T8 | F8W8T8_HUMAN | Acetyl-CoA carboxylase 2 | ACACB | 858 | Annotation score: | ||
H0YGH5 | H0YGH5_HUMAN | Acetyl-CoA carboxylase 2 | ACACB | 859 | Annotation score: | ||
F5H5C3 | F5H5C3_HUMAN | Acetyl-CoA carboxylase 2 | ACACB | 143 | Annotation score: | ||
A0A087WUA1 | A0A087WUA1_HUMAN | Acetyl-CoA carboxylase 2 | ACACB | 112 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 155 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC007637 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000544726; ENSP00000474680; ENSG00000076555 |
UCSCi | uc058sxt.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC007637 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | S4R3S7 |
PeptideAtlasi | S4R3S7 |
PRIDEi | S4R3S7 |
Protocols and materials databases
Antibodypediai | 1321, 182 antibodies |
Genome annotation databases
Ensembli | ENST00000544726; ENSP00000474680; ENSG00000076555 |
UCSCi | uc058sxt.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000076555.15 |
HGNCi | HGNC:85, ACACB |
OpenTargetsi | ENSG00000076555 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000155049 |
HOGENOMi | CLU_077570_1_0_1 |
Miscellaneous databases
ChiTaRSi | ACACB, human |
Gene expression databases
Bgeei | ENSG00000076555, Expressed in parietal pleura and 237 other tissues |
ExpressionAtlasi | S4R3S7, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR005481, BC-like_N IPR011764, Biotin_carboxylation_dom IPR016185, PreATP-grasp_dom_sf |
Pfami | View protein in Pfam PF00289, Biotin_carb_N, 1 hit |
SUPFAMi | SSF52440, SSF52440, 1 hit |
PROSITEi | View protein in PROSITE PS50979, BC, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | S4R3S7_HUMAN | |
Accessioni | S4R3S7Primary (citable) accession number: S4R3S7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 18, 2013 |
Last sequence update: | September 18, 2013 | |
Last modified: | December 2, 2020 | |
This is version 44 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |