Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 49 (05 Jun 2019)
Sequence version 1 (18 Sep 2013)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein
Submitted name:

Ankyrin-3

Gene

Ank3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Ankyrin-3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ank3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:88026 Ank3

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
S4R2K9

MaxQB - The MaxQuant DataBase

More...
MaxQBi
S4R2K9

PeptideAtlas

More...
PeptideAtlasi
S4R2K9

PRoteomics IDEntifications database

More...
PRIDEi
S4R2K9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000069601 Expressed in 286 organ(s), highest expression level in ventral horn of spinal cord

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
S4R2K9 baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
S4R2K9

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini40 – 823ANK_REP_REGIONInterPro annotationAdd BLAST784
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati73 – 105ANKPROSITE-ProRule annotationAdd BLAST33
Repeati106 – 138ANKPROSITE-ProRule annotationAdd BLAST33
Repeati139 – 171ANKPROSITE-ProRule annotationAdd BLAST33
Repeati172 – 195ANKPROSITE-ProRule annotationAdd BLAST24
Repeati242 – 274ANKPROSITE-ProRule annotationAdd BLAST33
Repeati275 – 307ANKPROSITE-ProRule annotationAdd BLAST33
Repeati308 – 340ANKPROSITE-ProRule annotationAdd BLAST33
Repeati341 – 373ANKPROSITE-ProRule annotationAdd BLAST33
Repeati374 – 406ANKPROSITE-ProRule annotationAdd BLAST33
Repeati407 – 439ANKPROSITE-ProRule annotationAdd BLAST33
Repeati440 – 472ANKPROSITE-ProRule annotationAdd BLAST33
Repeati473 – 505ANKPROSITE-ProRule annotationAdd BLAST33
Repeati506 – 538ANKPROSITE-ProRule annotationAdd BLAST33
Repeati539 – 571ANKPROSITE-ProRule annotationAdd BLAST33
Repeati572 – 604ANKPROSITE-ProRule annotationAdd BLAST33
Repeati605 – 637ANKPROSITE-ProRule annotationAdd BLAST33
Repeati638 – 670ANKPROSITE-ProRule annotationAdd BLAST33
Repeati671 – 703ANKPROSITE-ProRule annotationAdd BLAST33
Repeati704 – 736ANKPROSITE-ProRule annotationAdd BLAST33
Repeati737 – 769ANKPROSITE-ProRule annotationAdd BLAST33
Repeati770 – 802ANKPROSITE-ProRule annotationAdd BLAST33
Domaini992 – 1147ZU5InterPro annotationAdd BLAST156
Domaini1149 – 1296ZU5InterPro annotationAdd BLAST148
Domaini2335 – 2419DeathInterPro annotationAdd BLAST85

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 44DisorderedSequence analysisAdd BLAST44
Regioni870 – 889DisorderedSequence analysisAdd BLAST20
Regioni1510 – 1539DisorderedSequence analysisAdd BLAST30
Regioni1967 – 1991DisorderedSequence analysisAdd BLAST25
Regioni2098 – 2146DisorderedSequence analysisAdd BLAST49
Regioni2168 – 2200DisorderedSequence analysisAdd BLAST33
Regioni2291 – 2312DisorderedSequence analysisAdd BLAST22
Regioni2568 – 2622DisorderedSequence analysisAdd BLAST55

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 27PolyampholyteSequence analysisAdd BLAST27
Compositional biasi2102 – 2119PolyampholyteSequence analysisAdd BLAST18
Compositional biasi2120 – 2136PolarSequence analysisAdd BLAST17
Compositional biasi2579 – 2622PolyampholyteSequence analysisAdd BLAST44

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

ANK repeatPROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4177 Eukaryota
COG0666 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154939

Database of Orthologous Groups

More...
OrthoDBi
1011028at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00204 ANK, 7 hits
cd08803 Death_ank3, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.20, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037971 Ank3_Death
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR040745 Ankyrin_UPA
IPR011029 DEATH-like_dom_sf
IPR000488 Death_domain
IPR000906 ZU5_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00023 Ank, 3 hits
PF12796 Ank_2, 7 hits
PF00531 Death, 1 hit
PF17809 UPA_2, 1 hit
PF00791 ZU5, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01415 ANKYRIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248 ANK, 22 hits
SM00005 DEATH, 1 hit
SM00218 ZU5, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47986 SSF47986, 1 hit
SSF48403 SSF48403, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 21 hits
PS50017 DEATH_DOMAIN, 1 hit
PS51145 ZU5, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

This entry has 1 described isoform and 24 potential isoforms that are computationally mapped.Show allAlign All

S4R2K9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAHAASQLKK NRDLEINAEE ETEKKRKHRK RSRDRKKKSD ANASYLRAAR
60 70 80 90 100
AGHLEKALDY IKNGVDVNIC NQNGLNALHL ASKEGHVEVV SELLQREANV
110 120 130 140 150
DAATKKGNTA LHIASLAGQA EVVKVLVTNG ANVNAQSQNG FTPLYMAAQE
160 170 180 190 200
NHLEVVRFLL DNGASQSLAT EDGFTPLAVA LQQGHDQVVS LLLENDTKGK
210 220 230 240 250
VRLPALHIAA RKDDTKAAAL LLQNDTNADV ESKMVVNRAT ESGFTPLHIA
260 270 280 290 300
AHYGNINVAT LLLNRAAAVD FTARNDITPL HVASKRGNAN MVKLLLDRGA
310 320 330 340 350
KIDAKTRDGL TPLHCGARSG HEQVVEMLLD RSAPILSKTK NGLSPLHMAT
360 370 380 390 400
QGDHLNCVQL LLQHNVPVDD VTNDYLTALH VAAHCGHYKV AKVLLDKKAS
410 420 430 440 450
PNAKALNGFT PLHIACKKNR IRVMELLLKH GASIQAVTES GLTPIHVAAF
460 470 480 490 500
MGHVNIVSQL MHHGASPNTT NVRGETALHM AARSGQAEVV RYLVQDGAQV
510 520 530 540 550
EAKAKDDQTP LHISARLGKA DIVQQLLQQG ASPNAATTSG YTPLHLAARE
560 570 580 590 600
GHEDVAAFLL DHGASLSITT KKGFTPLHVA AKYGKLEVAS LLLQKSASPD
610 620 630 640 650
AAGKSGLTPL HVAAHYDNQK VALLLLDQGA SPHAAAKNGY TPLHIAAKKN
660 670 680 690 700
QMDIATSLLE YGADANAVTR QGIASVHLAA QEGHVDMVSL LLSRNANVNL
710 720 730 740 750
SNKSGLTPLH LAAQEDRVNV AEVLVNQGAH VDAQTKMGYT PLHVGCHYGN
760 770 780 790 800
IKIVNFLLQH SAKVNAKTKN GYTALHQAAQ QGHTHIINVL LQNNASPNEL
810 820 830 840 850
TVNGNTALAI ARRLGYISVV DTLKVVTEEI MTTTTITEKH KMNVPETMNE
860 870 880 890 900
VLDMSDDEVR KASAPEKLSD GEYISDGEEG EDAITGDTDK YLGPQDLKEL
910 920 930 940 950
GDDSLPAEGY VGFSLGARSA SLRSFSSDRS YTLNRSSYAR DSMMIEELLV
960 970 980 990 1000
PSKEQHLTFT REFDSDSLRH YSWAADTLDN VNLVSSPVHS GFLVSFMVDA
1010 1020 1030 1040 1050
RGGSMRGSRH HGMRIIIPPR KCTAPTRITC RLVKRHKLAN PPPMVEGEGL
1060 1070 1080 1090 1100
ASRLVEMGPA GAQFLGPVIV EIPHFGSMRG KERELIVLRS ENGETWKEHQ
1110 1120 1130 1140 1150
FDSKNEDLAE LLNGMDEELD SPEELGTKRI CRIITKDFPQ YFAVVSRIKQ
1160 1170 1180 1190 1200
ESNQIGPEGG ILSSTTVPLV QASFPEGALT KRIRVGLQAQ PVPEETVKKI
1210 1220 1230 1240 1250
LGNKATFSPI VTVEPRRRKF HKPITMTIPV PPPSGEGVSN GYKGDATPNL
1260 1270 1280 1290 1300
RLLCSITGGT SPAQWEDITG TTPLTFIKDC VSFTTNVSAR FWLADCHQVL
1310 1320 1330 1340 1350
ETVGLASQLY RELICVPYMA KFVVFAKTND PVESSLRCFC MTDDRVDKTL
1360 1370 1380 1390 1400
EQQENFEEVA RSKDIEVLEG KPIYVDCYGN LAPLTKGGQQ LVFNFYSFKE
1410 1420 1430 1440 1450
NRLPFSIKIR DTSQEPCGRL SFLKEPKTTK GLPQTAVCNL NITLPAHKKA
1460 1470 1480 1490 1500
EKADRRQSFA SLALRKRYSY LTEPSMKTVE RSSGTARSLP TTYSHKPFFS
1510 1520 1530 1540 1550
TRPYQSWTTA PITVPGPAKS GSLSSSPSNT PSASPLKSIW SVSTPSPIKS
1560 1570 1580 1590 1600
TLGASTTSSV KSISDVASPI RSFRTVSSPI KTVVSPSPYN PQVASGTLGR
1610 1620 1630 1640 1650
VPTITEATPI KGLAPNSTFS SRTSPVTTAG SLLERSSITM TPPASPKSNI
1660 1670 1680 1690 1700
TMYSSSLPFK SIITSATPLI SSPLKSVVSP TKSAADVIST AKATMASSLS
1710 1720 1730 1740 1750
SPLKQMSGHA EVALVNGSVS PLKYPSSSAL INGCKATATL QDKISTATNA
1760 1770 1780 1790 1800
VSSVVSAASD TVEKALSTTT AMPFSPLRSY VSAAPSAFQS LRTPSASALY
1810 1820 1830 1840 1850
TSLGSSIAAT TSSVTSSIIT VPVYSVVNVL PEPALKKLPD SNSFTKSAAA
1860 1870 1880 1890 1900
LLSPIKTLTT ETRPQPHFNR TSSPVKSSLF LASSALKPSV PSSLSSSQEI
1910 1920 1930 1940 1950
LKDVAEMKED LMRMTAILQT DVPEEKPFQT DLPREGRIDD EEPFKIVEKV
1960 1970 1980 1990 2000
KEDLVKVSEI LKKDVCVESK GPPKSPKSDK GHSPEDDWTE FSSEEIREAR
2010 2020 2030 2040 2050
QAAASHAPSL PERVHGKANL TRVIDYLTND IGSSSLTNLK YKFEEAKKDG
2060 2070 2080 2090 2100
EERQKRILKP AMALQEHKLK MPPASMRPST SEKELCKMAD SFFGADAILE
2110 2120 2130 2140 2150
SPDDFSQHDQ DKSPLSDSGF ETRSEKTPSA PQSAESTGPK PLFHEVPIPP
2160 2170 2180 2190 2200
VITETRTEVV HVIRSYEPSS GEIPQSQPED PVSPKPSPTF MELEPKPTTS
2210 2220 2230 2240 2250
SIKEKVKAFQ MKASSEEEDH SRVLSKGMRV KEETHITTTT RMVYHSPPGG
2260 2270 2280 2290 2300
ECASERIEET MSVHDIMKAF QSGRDPSKEL AGLFEHKSAM SPDVAKSAAE
2310 2320 2330 2340 2350
TSAQHAEKDS QMKPKLERII EVHIEKGPQS PCERTDIRMA IVADHLGLSW
2360 2370 2380 2390 2400
TELARELNFS VDEINQIRVE NPNSLISQSF MLLKKWVTRD GKNATTDALT
2410 2420 2430 2440 2450
SVLTKINRID IVTLLEGPIF DYGNISGTRS FADENNVFHD PVDGWQNETP
2460 2470 2480 2490 2500
SGSLESPAQA RRLTGGLLDR LDDSSDQARD SITSYLTGEP GKIEANGNHT
2510 2520 2530 2540 2550
AEVIPEAKAK PYFPESQNDI GKQSIKENLK PKTHGCGRTE EPVSPLTAYQ
2560 2570 2580 2590 2600
KSLEETSKLV IEDAPKPCVP VGMKKMTRTT ADGKARLNLQ EEEGSTRSEP
2610 2620
KQGEGYKVKT KKEIRNVEKK TH
Length:2,622
Mass (Da):284,644
Last modified:September 18, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8CF50483243C216A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 24 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G5E8K5ANK3_MOUSE
Ankyrin-3
Ank3
1,961Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G5E8K2G5E8K2_MOUSE
Ankyrin 3, epithelial, isoform CRA_...
Ank3 mCG_14429
1,940Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R2S8S4R2S8_MOUSE
Ankyrin-3
Ank3
1,985Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G5E8K3G5E8K3_MOUSE
Ankyrin 3, epithelial, isoform CRA_...
Ank3 mCG_14429
1,943Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R236S4R236_MOUSE
Ankyrin-3
Ank3
1,181Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R1S2S4R1S2_MOUSE
Ankyrin-3
Ank3
1,807Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R165S4R165_MOUSE
Ankyrin-3
Ank3
1,174Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R2J6S4R2J6_MOUSE
Ankyrin-3
Ank3
1,157Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1W2P812A0A1W2P812_MOUSE
Ankyrin-3
Ank3
1,758Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R208S4R208_MOUSE
Ankyrin-3
Ank3
556Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei2622Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC100427 Genomic DNA No translation available.
AC129018 Genomic DNA No translation available.
AC131795 Genomic DNA No translation available.
AC132435 Genomic DNA No translation available.
AC156836 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_006513196.1, XM_006513133.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000182992; ENSMUSP00000138686; ENSMUSG00000069601

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
11735

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC100427 Genomic DNA No translation available.
AC129018 Genomic DNA No translation available.
AC131795 Genomic DNA No translation available.
AC132435 Genomic DNA No translation available.
AC156836 Genomic DNA No translation available.
RefSeqiXP_006513196.1, XM_006513133.2

3D structure databases

SMRiS4R2K9
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

jPOSTiS4R2K9
MaxQBiS4R2K9
PeptideAtlasiS4R2K9
PRIDEiS4R2K9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000182992; ENSMUSP00000138686; ENSMUSG00000069601
GeneIDi11735

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
288
MGIiMGI:88026 Ank3

Phylogenomic databases

eggNOGiKOG4177 Eukaryota
COG0666 LUCA
GeneTreeiENSGT00940000154939
OrthoDBi1011028at2759

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Ank3 mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000069601 Expressed in 286 organ(s), highest expression level in ventral horn of spinal cord
ExpressionAtlasiS4R2K9 baseline and differential

Family and domain databases

CDDicd00204 ANK, 7 hits
cd08803 Death_ank3, 1 hit
Gene3Di1.25.40.20, 3 hits
InterProiView protein in InterPro
IPR037971 Ank3_Death
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR040745 Ankyrin_UPA
IPR011029 DEATH-like_dom_sf
IPR000488 Death_domain
IPR000906 ZU5_dom
PfamiView protein in Pfam
PF00023 Ank, 3 hits
PF12796 Ank_2, 7 hits
PF00531 Death, 1 hit
PF17809 UPA_2, 1 hit
PF00791 ZU5, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 22 hits
SM00005 DEATH, 1 hit
SM00218 ZU5, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
SSF48403 SSF48403, 3 hits
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 21 hits
PS50017 DEATH_DOMAIN, 1 hit
PS51145 ZU5, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS4R2K9_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: S4R2K9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 18, 2013
Last sequence update: September 18, 2013
Last modified: June 5, 2019
This is version 49 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again