UniProtKB - S4R299 (S4R299_MOUSE)
Protein
Submitted name:
Zinc finger protein 236
Gene
Zfp236
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor activity Source: GO_Central
GO - Biological processi
- regulation of transcription, DNA-templated Source: GO_Central
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Zinc finger protein 236Imported |
Gene namesi | Name:Zfp236Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1926950, Zfp236 |
Subcellular locationi
Nucleus
- nucleus Source: GO_Central
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000041258, Expressed in blood and 255 other tissues |
ExpressionAtlasi | S4R299, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 39 – 67 | C2H2-typeInterPro annotationAdd BLAST | 29 | |
Domaini | 68 – 95 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 95 – 122 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 123 – 150 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 155 – 182 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 199 – 226 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 227 – 254 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 255 – 283 | C2H2-typeInterPro annotationAdd BLAST | 29 | |
Domaini | 287 – 315 | C2H2-typeInterPro annotationAdd BLAST | 29 | |
Domaini | 484 – 511 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 512 – 539 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 540 – 567 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 568 – 598 | C2H2-typeInterPro annotationAdd BLAST | 31 | |
Domaini | 659 – 686 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 687 – 714 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 715 – 742 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 743 – 770 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 970 – 997 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 998 – 1025 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 1026 – 1053 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 1054 – 1081 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 1170 – 1197 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 1198 – 1225 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 1226 – 1253 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 1254 – 1281 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 1660 – 1688 | C2H2-typeInterPro annotationAdd BLAST | 29 | |
Domaini | 1689 – 1716 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 1725 – 1752 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 1753 – 1780 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 1781 – 1805 | C2H2-typeInterPro annotationAdd BLAST | 25 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 21 | DisorderedSequence analysisAdd BLAST | 21 | |
Regioni | 409 – 468 | DisorderedSequence analysisAdd BLAST | 60 | |
Regioni | 853 – 886 | DisorderedSequence analysisAdd BLAST | 34 | |
Regioni | 1089 – 1113 | DisorderedSequence analysisAdd BLAST | 25 | |
Regioni | 1270 – 1297 | DisorderedSequence analysisAdd BLAST | 28 | |
Regioni | 1465 – 1490 | DisorderedSequence analysisAdd BLAST | 26 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 1145 – 1165 | Sequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 15 | PolyampholyteSequence analysisAdd BLAST | 15 | |
Compositional biasi | 416 – 435 | PolarSequence analysisAdd BLAST | 20 | |
Compositional biasi | 441 – 467 | PolyampholyteSequence analysisAdd BLAST | 27 | |
Compositional biasi | 870 – 886 | PolarSequence analysisAdd BLAST | 17 | |
Compositional biasi | 1270 – 1289 | PolyampholyteSequence analysisAdd BLAST | 20 |
Keywords - Domaini
Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
GeneTreei | ENSGT00940000156787 |
OrthoDBi | 1318335at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00096, zf-C2H2, 18 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 30 hits |
SUPFAMi | SSF57667, SSF57667, 15 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 30 hits PS50157, ZINC_FINGER_C2H2_2, 30 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
S4R299-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPRGRPPKPR DGAARGDSDG VLALNDEDID DDCPIPNFHK CEICLLSFPK
60 70 80 90 100
ESQFQRHMRE HEQNDKPHRC DQCPQTFNVE FNLTLHKCTH NAEDPVCPVC
110 120 130 140 150
NKKFSRVASL KAHIMLHEKE ENLICSECGD EFTLHSQLAI HMEEHRQELA
160 170 180 190 200
NTRAHTCKAC KKEFETSPEL KEHMKTHCKV RASGTRSYNR NIDRSSFPYS
210 220 230 240 250
CPHCGKTFQK PSQLTRHIRI HTGERPFKCS ECGKAFNQKG ALQTHMIKHT
260 270 280 290 300
GEKPHACAFC PAAFSQKGNL QSHVQRVHSE VKNGPTYNCT ECSCVFKSLG
310 320 330 340 350
SLNTHISKMH MGGPPNSTTS AETAHVITAT IFQTLPLQQV EAQVSSVSSE
360 370 380 390 400
QSSQAVSDVI QQLLELSEPG PVEAQQSPQS GRQLSVTVGI NQDILQQALE
410 420 430 440 450
NSGLSSLPVA APPSDCSHAQ TATVSTQSPH ASSVSAEQAD PMDAEQEKGQ
460 470 480 490 500
ESPEKTDKKE KKLLKKKSPF LPGSIREENG VRWHVCPYCT KEFRKPSDLV
510 520 530 540 550
RHIRIHTHEK PFKCPQCFRA FAVKSTLTAH IKTHTGIKAF KCQYCMKSFS
560 570 580 590 600
TSGSLKVHIR LHTGVRPFAC PHCDKKFRTS GHRKTHVASH FKHTELRKLR
610 620 630 640 650
QQRKPVKGRV GKSSVPVPDI PLQEPILITD LGLIQPIPKN QFFQNYFNNS
660 670 680 690 700
FGNEADRPYK CFYCHRAYKK SCHLKQHIRS HTGEKPFKCS QCGRGFVSAG
710 720 730 740 750
VLKAHVRTHT GLKSFKCLIC NGAFTTGGSL RRHMGIHNDL RPYMCPYCQK
760 770 780 790 800
TFKTSLNCKK HMKTHRYELA QQLQQHQEAS SMDDDSTVDQ QSMHVAAPMP
810 820 830 840 850
VEIESAELQQ TPETVAADPE SILELGPQHV VGTEDAALGQ QLADQPLEAD
860 870 880 890 900
EDGFTASQAP LPGHMDQFEE QGTPQPSFES AGLPQGFTVT DTYSQQTSFP
910 920 930 940 950
PVQQLQDSST LESQALSTSF HQQNLLQVPN SDAINVATRL LPESSQEDLD
960 970 980 990 1000
LQTQGPQFLE DSEDQSRRSY RCDYCNKGFK KSSHLKQHVR SHTGEKPYKC
1010 1020 1030 1040 1050
KLCGRAFVSS GVLKSHEKTH TGVKAFSCSI CNASFTTNGS LTRHMATHMS
1060 1070 1080 1090 1100
MKPYKCPFCE EGFRTAVHCR KHMKRHQAVS SAAAAAAETE GGDTCVEEDE
1110 1120 1130 1140 1150
ENSDRSASRK PRPEVITFTE EETAQLAKIQ PQESATVSEK VLVQSAAEKD
1160 1170 1180 1190 1200
RISEMKDKQA ELEAEPKHAN CCTYCPKSFK KPSDLVRHVR IHTGEKPYKC
1210 1220 1230 1240 1250
DECGKSFTVK STLDCHVKTH TGQKLFSCHV CSNAFSTKGS LKVHMRLHTG
1260 1270 1280 1290 1300
AKPFKCPHCE LRFRTSGRRK THMQFHYKSD PKKARKPVTR SSSESLQSVN
1310 1320 1330 1340 1350
LLNSSSTDPN VFIMNNSVLT GQFDQNVLQP GLVGQAILPA SVSAGGDLTV
1360 1370 1380 1390 1400
SLTDGSLATL EGIQLQLAAN LVGPNVQISG IDASSINNIT LQIDPSILQQ
1410 1420 1430 1440 1450
TLQQGSLLAQ PITGESSTAS QNSSLQTSDS TVPASVVIQP LSGLSLQPTV
1460 1470 1480 1490 1500
TSANLTIGPL SEQDSVLTTS SSGSQDLSQV MTSQGLVSTS TGPHEITLTI
1510 1520 1530 1540 1550
NNSSLSQVLA QAAGPTASSS SGSPQEITLT ISELNPSSGS LPSTAPMSPS
1560 1570 1580 1590 1600
AISAQNLVMS SSGVGADASV TLTLADTQGV LSGGLDTVTL NITSQGQQFP
1610 1620 1630 1640 1650
ALLTDPSLSG QGGAGSPQVI LVSHTPQSSS AAGEEIAYQV TDVPAQLTPH
1660 1670 1680 1690 1700
SQPEKEGLSH QCLDCDRAFS SAAVLMHHSK EVHGKERIHG CRVCRKAFKR
1710 1720 1730 1740 1750
ATHLKEHMLT HQAGPSLSSQ KPRVFKCDSC EKAFAKPSQL ERHSRIHTGE
1760 1770 1780 1790 1800
RPFHCTLCDK AFNQKSALQV HLKKHTGERP YRCDYCVMGF TQKSNMKLHM
1810 1820 1830 1840
KRAHSFVGTL QAATVVQEQD GDELRTLHLE EVVPEAAGEW QTLTNVF
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketB2RR24 | B2RR24_MOUSE | Zinc finger protein 236 | Zfp236 | 1,799 | Annotation score: | ||
S4R1D8 | S4R1D8_MOUSE | Zinc finger protein 236 | Zfp236 | 485 | Annotation score: | ||
S4R1R9 | S4R1R9_MOUSE | Zinc finger protein 236 | Zfp236 | 429 | Annotation score: | ||
S4R1Z3 | S4R1Z3_MOUSE | Zinc finger protein 236 | Zfp236 | 43 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC119259 Genomic DNA No translation available. AC158975 Genomic DNA No translation available. |
RefSeqi | XP_006526553.1, XM_006526490.3 |
Genome annotation databases
Ensembli | ENSMUST00000182122; ENSMUSP00000138557; ENSMUSG00000041258 |
GeneIDi | 329002 |
UCSCi | uc012bfp.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC119259 Genomic DNA No translation available. AC158975 Genomic DNA No translation available. |
RefSeqi | XP_006526553.1, XM_006526490.3 |
3D structure databases
SMRi | S4R299 |
ModBasei | Search... |
Proteomic databases
MaxQBi | S4R299 |
Protocols and materials databases
Antibodypediai | 1786, 39 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000182122; ENSMUSP00000138557; ENSMUSG00000041258 |
GeneIDi | 329002 |
UCSCi | uc012bfp.1, mouse |
Organism-specific databases
CTDi | 329002 |
MGIi | MGI:1926950, Zfp236 |
Phylogenomic databases
GeneTreei | ENSGT00940000156787 |
OrthoDBi | 1318335at2759 |
Miscellaneous databases
BioGRID-ORCSi | 329002, 4 hits in 12 CRISPR screens |
ChiTaRSi | Zfp236, mouse |
RNActi | S4R299, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000041258, Expressed in blood and 255 other tissues |
ExpressionAtlasi | S4R299, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00096, zf-C2H2, 18 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 30 hits |
SUPFAMi | SSF57667, SSF57667, 15 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 30 hits PS50157, ZINC_FINGER_C2H2_2, 30 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | S4R299_MOUSE | |
Accessioni | S4R299Primary (citable) accession number: S4R299 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 18, 2013 |
Last sequence update: | September 18, 2013 | |
Last modified: | February 10, 2021 | |
This is version 56 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |