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Entry version 52 (02 Jun 2021)
Sequence version 1 (18 Sep 2013)
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Protein
Submitted name:

Rho guanine nucleotide exchange factor 40

Gene

Arhgef40

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Rho guanine nucleotide exchange factor 40Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Arhgef40Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2685515, Arhgef40

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
S4R189

MaxQB - The MaxQuant DataBase

More...
MaxQBi
S4R189

PeptideAtlas

More...
PeptideAtlasi
S4R189

PRoteomics IDEntifications database

More...
PRIDEi
S4R189

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
370035

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000004562, Expressed in uterus and 250 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
S4R189, baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
S4R189

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1092 – 1260DHInterPro annotationAdd BLAST169
Domaini1272 – 1379PHInterPro annotationAdd BLAST108

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni194 – 238DisorderedSequence analysisAdd BLAST45
Regioni254 – 514DisorderedSequence analysisAdd BLAST261
Regioni961 – 1020DisorderedSequence analysisAdd BLAST60
Regioni1473 – 1526DisorderedSequence analysisAdd BLAST54

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili769 – 799Sequence analysisAdd BLAST31
Coiled coili861 – 881Sequence analysisAdd BLAST21
Coiled coili1236 – 1256Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi202 – 216Pro residuesSequence analysisAdd BLAST15
Compositional biasi275 – 290Basic residuesSequence analysisAdd BLAST16
Compositional biasi303 – 318Polar residuesSequence analysisAdd BLAST16
Compositional biasi423 – 473Basic and acidic residuesSequence analysisAdd BLAST51
Compositional biasi474 – 505Polar residuesSequence analysisAdd BLAST32
Compositional biasi961 – 980Basic and acidic residuesSequence analysisAdd BLAST20
Compositional biasi984 – 1002Polar residuesSequence analysisAdd BLAST19
Compositional biasi1496 – 1526Polar residuesSequence analysisAdd BLAST31

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161599

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001356_2_1_1

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.900.10, 1 hit
2.30.29.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR035899, DBL_dom_sf
IPR000219, DH-domain
IPR011993, PH-like_dom_sf
IPR001849, PH_domain

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00621, RhoGEF, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00233, PH, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48065, SSF48065, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50010, DH_2, 1 hit
PS50003, PH_DOMAIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.Show allAlign All

S4R189-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEPEPVEDCV QSTLAALYPP FEATAPTLLG QVFQVVERTY QEDALRYTLD
60 70 80 90 100
FLVPAKHLLA KVQQEACAQY SGFLFFHEGW PLCLHEQVVV QLAALPWQLL
110 120 130 140 150
RPGDFYLQVV PSAAQAPRLA LKCLAPGGGR VQELPVPSEA CAYLFTPEWL
160 170 180 190 200
QGINKDRPTG RLSTCLLSAP SGIQRLPWAE LVCPRFVHKE GLMVGHQPST
210 220 230 240 250
LPPELPSGPP GLPSSPLPEE VLGTRSPGDG HNAPAEGPEG EYVELLEVTL
260 270 280 290 300
PVRGSPVDAE ASGLSRTRTV PARKSTGGKG RHRRHRAWMN QKGLGSRDQD
310 320 330 340 350
GTRPPGEGSS TGASSDSPSG AEADPDATAL QASEPPAEAL GEAPESCLLS
360 370 380 390 400
GEAVGGVGQG AEGPPGTPRR TGKGNRRKKR AAGRGAGSRG GEGTSLSPRD
410 420 430 440 450
KEETRQQEVL VSLPSPSEQE PAECSLVKEK EDSGKQESES KEELKPADEK
460 470 480 490 500
EPARPEDYEP PEEEIRESEK EELTPQCTAG STGPEWFPSE PSTQPLETVQ
510 520 530 540 550
NVKGDSLPEE TPPVSVLDDP VVAWDLMASG FFVLTGGVDQ TGRALLTITP
560 570 580 590 600
PPPCLPEESS PSQETLSTAL RYLHSLLRPD LQLLGLTILL DLRKAPPLPP
610 620 630 640 650
ALLPALSQLQ CRDILLCPQD SGEPPLIQRL VILIHEDPPA ELCGFQGAEL
660 670 680 690 700
LSEKDLKRVA KPEELQWDLG GHRDLSPNHW AEIHQEVARL CTLCQGVLTS
710 720 730 740 750
VRQAIEELEG TAEPKEEEAV GMPEPLQKVL ADPRLTALQR NGGAILMRLR
760 770 780 790 800
SAHSSKLEGP GPAELYQEVD EAIHQLVRLS NLRVQQQEER QRLRQVQQVL
810 820 830 840 850
QWLSGPGEEQ LASFSMPGNS LSVLQETELR FRAFSTEVQE RLVQAREALA
860 870 880 890 900
LEEDLTSQKV LDIFEQRLEQ AESGLHRALR LQRFFQQAHE WVDEGSARLA
910 920 930 940 950
GAGSGREALL AALALRRAPE PSAGTFQEMR ALALDLGSPA ALREWGRCRA
960 970 980 990 1000
RCQELERRIQ QQLGEEASPR SHRRRRADSA SSAGAQHGAH SPSPSLSSLL
1010 1020 1030 1040 1050
LPSSPGPRAA PSHCSLTPCG EDYEEEGLEL APETDGRPPR AVLIRGLEVT
1060 1070 1080 1090 1100
STEVVDRTCS PREHVLLGRA GGPDGPWGIG TPRMERKRSI SAQQRLVSEL
1110 1120 1130 1140 1150
IACEQEYVTT LNEPVPLPGP ELTPELRCTW AAALSVRERL RSFHGTHFLQ
1160 1170 1180 1190 1200
ELQGCAAHPL RIGACFLRHG DQFNLYAQFV KHRHKLESGL AALTPSVKGS
1210 1220 1230 1240 1250
MESSPCLPRA LQQPLEQLAR YGQLLEELLR EAGPELSSER QALRAAVQLL
1260 1270 1280 1290 1300
QEQEARGRDL LAVEAVRGCE IDLKEQGQLL HRDPFTVICG RKKCLRHVFL
1310 1320 1330 1340 1350
FEDLLLFSKL KGSEGGSETF VYKQAFKTAD MGLTENIGDS GLCFELWFRR
1360 1370 1380 1390 1400
RRAREAYTLQ ATSPETKLKW TSSIAQLLWR QAAHNKELRV QQMVSMGIGN
1410 1420 1430 1440 1450
KPFLDIKALG ERTLSALLTG RAARTRASVA VSSFEHAGPS LPGLSPGACS
1460 1470 1480 1490 1500
LPARVEEEAW DLDVKQISLA SETLDSSGDV SPGPRNSPSL QPPSPGSSTP
1510 1520
ALTSGGILGL SRQSHSRALS DPTTPL
Length:1,526
Mass (Da):166,175
Last modified:September 18, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD3EFA176CB27A8EC
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q3UPH7ARH40_MOUSE
Rho guanine nucleotide exchange fac...
Arhgef40 Solo
1,517Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R2U9S4R2U9_MOUSE
Rho guanine nucleotide exchange fac...
Arhgef40
1,191Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R1Y4S4R1Y4_MOUSE
Rho guanine nucleotide exchange fac...
Arhgef40
179Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R1S6S4R1S6_MOUSE
Rho guanine nucleotide exchange fac...
Arhgef40
500Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R2A6S4R2A6_MOUSE
Rho guanine nucleotide exchange fac...
Arhgef40
115Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R1R5S4R1R5_MOUSE
Rho guanine nucleotide exchange fac...
Arhgef40
73Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R2R3S4R2R3_MOUSE
Rho guanine nucleotide exchange fac...
Arhgef40
89Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R1X0S4R1X0_MOUSE
Rho guanine nucleotide exchange fac...
Arhgef40
45Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R237S4R237_MOUSE
Rho guanine nucleotide exchange fac...
Arhgef40
85Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R2G8S4R2G8_MOUSE
Rho guanine nucleotide exchange fac...
Arhgef40
44Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000182760; ENSMUSP00000138125; ENSMUSG00000004562

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

SMRiS4R189
ModBaseiSearch...

Proteomic databases

jPOSTiS4R189
MaxQBiS4R189
PeptideAtlasiS4R189
PRIDEiS4R189
ProteomicsDBi370035

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
22091, 31 antibodies

Genome annotation databases

EnsembliENSMUST00000182760; ENSMUSP00000138125; ENSMUSG00000004562

Organism-specific databases

MGIiMGI:2685515, Arhgef40

Phylogenomic databases

GeneTreeiENSGT00940000161599
HOGENOMiCLU_001356_2_1_1

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Arhgef40, mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000004562, Expressed in uterus and 250 other tissues
ExpressionAtlasiS4R189, baseline and differential

Family and domain databases

Gene3Di1.20.900.10, 1 hit
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR035899, DBL_dom_sf
IPR000219, DH-domain
IPR011993, PH-like_dom_sf
IPR001849, PH_domain
PfamiView protein in Pfam
PF00621, RhoGEF, 1 hit
SMARTiView protein in SMART
SM00233, PH, 1 hit
SUPFAMiSSF48065, SSF48065, 1 hit
PROSITEiView protein in PROSITE
PS50010, DH_2, 1 hit
PS50003, PH_DOMAIN, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS4R189_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: S4R189
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 18, 2013
Last sequence update: September 18, 2013
Last modified: June 2, 2021
This is version 52 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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