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Protein
Submitted name:

DNA-binding protein Ikaros

Gene

IKZF1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
DNA-binding protein IkarosImported
Submitted name:
IKAROS family zinc finger 1 isoform 14Imported
Gene namesi
Name:IKZF1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000185811.16
HGNCiHGNC:13176 IKZF1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000185811

PTM / Processingi

Proteomic databases

PRIDEiR9R4D9

Expressioni

Gene expression databases

BgeeiENSG00000185811

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini78 – 100C2H2-typeInterPro annotationAdd BLAST23

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00550000074392
KOiK09220

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 3 hits
SUPFAMiSSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 2 hits
PS50157 ZINC_FINGER_C2H2_2, 1 hit

Sequencei

Sequence statusi: Complete.

R9R4D9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDADEGQDMS QVSGKESPPV SDTPDEGDEP MPIPEDLSTT SGGQQSSKSD
60 70 80 90 100
RVVVTYGADD FRDFHAIIPK SFSRERPFQC NQCGASFTQK GNLLRHIKLH
110 120 130 140 150
KPLAEGTPRS NHSAQDSAVE NLLLLSKAKL VPSEREASPS NSCQDSTDTE
160 170 180 190 200
SNNEEQRSGL IYLTNHIAPH ARNGLSLKEE HRAYDLLRAA SENSQDALRV
210 220 230 240 250
VSTSGEQMKV YKCEHCRVLF LDHVMYTIHM GCHGFRDPFE CNMCGYHSQD
260
RYEFSSHITR GEHRFHMS
Length:268
Mass (Da):30,031
Last modified:September 18, 2013 - v1
Checksum:i3A4F6647250035C0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124014 Genomic DNA No translation available.
AC233268 Genomic DNA No translation available.
AUXG01000057 Genomic DNA No translation available.
JX459579 mRNA Translation: AGI59420.1
RefSeqiNP_001207694.1, NM_001220765.2
NP_001207696.1, NM_001220767.2
NP_001207697.1, NM_001220768.2
NP_001207699.1, NM_001220770.2
NP_001207700.1, NM_001220771.2
NP_001278766.1, NM_001291837.1
NP_001278767.1, NM_001291838.1
NP_001278768.1, NM_001291839.1
NP_001278769.1, NM_001291840.1
NP_001278770.1, NM_001291841.1
NP_001278771.1, NM_001291842.1
NP_001278772.1, NM_001291843.1
NP_001278773.1, NM_001291844.1
NP_006051.1, NM_006060.5
UniGeneiHs.435949
Hs.488251
Hs.646004
Hs.731495

Genome annotation databases

EnsembliENST00000612658; ENSP00000483016; ENSG00000185811
GeneIDi10320
KEGGihsa:10320
UCSCiuc064dpn.1 human

Similar proteinsi

Entry informationi

Entry nameiR9R4D9_HUMAN
AccessioniPrimary (citable) accession number: R9R4D9
Entry historyiIntegrated into UniProtKB/TrEMBL: September 18, 2013
Last sequence update: September 18, 2013
Last modified: July 18, 2018
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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