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Entry version 64 (10 Feb 2021)
Sequence version 1 (24 Jul 2013)
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Protein
Submitted name:

Wing blister, isoform G

Gene

wb

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Wing blister, isoform GImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:wbImported
Synonyms:&agr1Imported, 2Imported, 2]]Imported, 2LanImported, A1Imported, alpha2Imported, alpha[[1Imported, BEST:CK02229Imported, BG:DS03792.1Imported, BG:DS03792.2Imported, CG15288Imported, CG32970Imported, CK02229Imported, CT35236Imported, DLAMImported, Dmel\CG42677Imported, fus5Imported, l(2)09437Imported, l(2)34FbImported, l(2)br1Imported, l34FbImported, LanA1Imported, LM-AImported, WbImported
ORF Names:CG42677Imported, Dmel_CG42677Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2L

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0261563, wb

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Extracellular matrixARBA annotation, Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 24Sequence analysisAdd BLAST24
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500448823725 – 3001Sequence analysisAdd BLAST2977

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi475 ↔ 484PROSITE-ProRule annotation
Disulfide bondi526 ↔ 535PROSITE-ProRule annotation
Disulfide bondi570 ↔ 579PROSITE-ProRule annotation
Disulfide bondi871 ↔ 880PROSITE-ProRule annotation
Disulfide bondi944 ↔ 953PROSITE-ProRule annotation
Disulfide bondi991 ↔ 1000PROSITE-ProRule annotation
Disulfide bondi1018 ↔ 1030PROSITE-ProRule annotation
Disulfide bondi1020 ↔ 1037PROSITE-ProRule annotation
Disulfide bondi1039 ↔ 1048PROSITE-ProRule annotation
Disulfide bondi1087 ↔ 1096PROSITE-ProRule annotation
Disulfide bondi1150 ↔ 1162PROSITE-ProRule annotation
Disulfide bondi1152 ↔ 1169PROSITE-ProRule annotation
Disulfide bondi1171 ↔ 1180PROSITE-ProRule annotation
Disulfide bondi1199 ↔ 1211PROSITE-ProRule annotation
Disulfide bondi1201 ↔ 1218PROSITE-ProRule annotation
Disulfide bondi1220 ↔ 1229PROSITE-ProRule annotation
Disulfide bondi1266 ↔ 1275PROSITE-ProRule annotation
Disulfide bondi1294 ↔ 1306PROSITE-ProRule annotation
Disulfide bondi1296 ↔ 1313PROSITE-ProRule annotation
Disulfide bondi1315 ↔ 1324PROSITE-ProRule annotation
Disulfide bondi1365 ↔ 1374PROSITE-ProRule annotation
Disulfide bondi1689 ↔ 1698PROSITE-ProRule annotation
Disulfide bondi1701 ↔ 1715PROSITE-ProRule annotation
Disulfide bondi1742 ↔ 1751PROSITE-ProRule annotation
Disulfide bondi1773 ↔ 1785PROSITE-ProRule annotation
Disulfide bondi1775 ↔ 1792PROSITE-ProRule annotation
Disulfide bondi1794 ↔ 1803PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationARBA annotation, GlycoproteinARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0261563, Expressed in embryo and 34 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
R9PY40, baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
R9PY40

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini149 – 399Laminin N-terminalInterPro annotationAdd BLAST251
Domaini452 – 505Laminin EGF-likeInterPro annotationAdd BLAST54
Domaini506 – 549Laminin EGF-likeInterPro annotationAdd BLAST44
Domaini550 – 599Laminin EGF-likeInterPro annotationAdd BLAST50
Domaini620 – 814Laminin IV type AInterPro annotationAdd BLAST195
Domaini852 – 901Laminin EGF-likeInterPro annotationAdd BLAST50
Domaini902 – 973Laminin EGF-likeInterPro annotationAdd BLAST72
Domaini974 – 1017Laminin EGF-likeInterPro annotationAdd BLAST44
Domaini1018 – 1064Laminin EGF-likeInterPro annotationAdd BLAST47
Domaini1065 – 1109Laminin EGF-likeInterPro annotationAdd BLAST45
Domaini1150 – 1198Laminin EGF-likeInterPro annotationAdd BLAST49
Domaini1199 – 1246Laminin EGF-likeInterPro annotationAdd BLAST48
Domaini1247 – 1293Laminin EGF-likeInterPro annotationAdd BLAST47
Domaini1294 – 1339Laminin EGF-likeInterPro annotationAdd BLAST46
Domaini1340 – 1394Laminin EGF-likeInterPro annotationAdd BLAST55
Domaini1435 – 1627Laminin IV type AInterPro annotationAdd BLAST193
Domaini1670 – 1717Laminin EGF-likeInterPro annotationAdd BLAST48
Domaini1718 – 1772Laminin EGF-likeInterPro annotationAdd BLAST55
Domaini1773 – 1820Laminin EGF-likeInterPro annotationAdd BLAST48
Domaini2584 – 2772LAM_G_DOMAINInterPro annotationAdd BLAST189
Domaini2776 – 2995LAM_G_DOMAINInterPro annotationAdd BLAST220

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni65 – 89DisorderedSequence analysisAdd BLAST25
Regioni106 – 134DisorderedSequence analysisAdd BLAST29

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili2034 – 2068Sequence analysisAdd BLAST35
Coiled coili2278 – 2308Sequence analysisAdd BLAST31
Coiled coili2359 – 2379Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Laminin EGF-like domainPROSITE-ProRule annotationARBA annotation, RepeatARBA annotation, SignalSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000167067

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000301_0_0_1

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.1490, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013320, ConA-like_dom_sf
IPR000742, EGF-like_dom
IPR002049, Laminin_EGF
IPR001791, Laminin_G
IPR000034, Laminin_IV
IPR008211, Laminin_N
IPR038684, Laminin_N_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00052, Laminin_B, 2 hits
PF00053, Laminin_EGF, 16 hits
PF02210, Laminin_G_2, 2 hits
PF00055, Laminin_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00181, EGF, 9 hits
SM00180, EGF_Lam, 17 hits
SM00281, LamB, 2 hits
SM00282, LamG, 3 hits
SM00136, LamNT, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49899, SSF49899, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00022, EGF_1, 1 hit
PS01248, EGF_LAM_1, 6 hits
PS50027, EGF_LAM_2, 16 hits
PS50025, LAM_G_DOMAIN, 2 hits
PS51115, LAMININ_IVA, 2 hits
PS51117, LAMININ_NTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

R9PY40-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQIGNFIKWP LGLILILLVT HCQAKRQRKR LRGFSTAKDL QDYSMPLNDN
60 70 80 90 100
STELQQNIVS WTGARIASSP DKKKKSPQSS RRHKTKSGLI IESNIADSES
110 120 130 140 150
MLAIASSESV TKKKPPQRRR NGKLQKSGGG AGGGALRLLK TEDVYSSSFS
160 170 180 190 200
GGLYPPLFNV VPRAQISVNA TCGQNGAEEY CKQVGAKPCG ICNAHSSDRA
210 220 230 240 250
KQRSIQSLIS SGSGSGSGSG FEEGWWQSPT LQGGRQFEYV TILLDLKQTF
260 270 280 290 300
QIFSVWLKSA NSPRPASWIL EKSLDGINFE PWQYFGLSDA DCQRRWNLSG
310 320 330 340 350
QNGKYVFQND TEIICSTQFS KPGPLENGVL HASLLKNRPG ATDQSPELMK
360 370 380 390 400
FITTRYIRIR LQGMHSTANQ DNSLDWLLDS PSLEKHSFYS LSQLKVSARL
410 420 430 440 450
DCNGHANRSH ESPDDPLMQC ICQHNTCGAQ CEQCCPLFQD RPYQMGGECE
460 470 480 490 500
ICQCYGHAES CTYDPFLDKG ICQSCSNNTA GIECEFCEMG FYRELDAPLT
510 520 530 540 550
DPCLPCSCNP ARSTGGCQSD GGSCNCLEGF QGKNCEECAP GYYGDDCKRC
560 570 580 590 600
ECDERGSLGS TGSCSGVCQC KLNVEGSTCS ECAPGYFDLS AENAEGCTSC
610 620 630 640 650
WCSGVSQTCH SAKLQTLAFE TLNDWKITDI QRVKPISIPV DAETNRLIFA
660 670 680 690 700
NELDEVEAIY WQASLGYLGN RLTSYGSRLQ LVLSWDVIRG DRSGKPTTGP
710 720 730 740 750
NVILVGKNGL KIAFGDESLD GLGINLNVTL TEVGWYHVPP TVVDIKTRLR
760 770 780 790 800
RTEGGDYHGE SVTRSQFLSV LVSLDAVLIR AAFHTDQGET SLERAVIYSG
810 820 830 840 850
GVELGGKSSS QVEQCLCPAG YTGLSCEGCA FGFKRIYENT SDHQILSKCI
860 870 880 890 900
PCPCNGHSNS CDLQSGNCGD CMHNTFGDRC ERCQLGYYGN PLQGTPNDCK
910 920 930 940 950
RCACPLSEDS NNFSPSCQLK SYNYMDLNPQ FELIEHAEYI CTQCPEGYTG
960 970 980 990 1000
DHCQVCDDGY FGNPRQPGSS CQRCDCAGGP CNVTTGECIT CRGNTEGWHC
1010 1020 1030 1040 1050
ERCKLGYWGD PAVGCDPCHC HTEGSESGLC DSTDGQCLCK PRYAGQKCDE
1060 1070 1080 1090 1100
CDVGYANVEL RCPSCNCDPL GSLVQDRCDP HTGQCHCKEG VMGAKCHECQ
1110 1120 1130 1140 1150
DGYFGMNAVA YRMDDLAALR QNSDSDDDEW ELVPDTEDPN SESTVACEEC
1160 1170 1180 1190 1200
HCSSVGSLSS DCDKRTGQCA CLANVTGRRC DKCRPGHWNL TAGEGCRDCR
1210 1220 1230 1240 1250
CDPHGSRGHE CNPWTGQCDC KIGVGGQHCN ECTEGFFGFS TEGCQRCSAC
1260 1270 1280 1290 1300
RSEGQVCDPH NGRCICPKFT RGLGCGQCVP GTWGWQARLG CRECECDHIG
1310 1320 1330 1340 1350
SIGQQCSTGD GQCQCREGYS GRKCDTCAIG YFGYPECRRC GCDAEGSFTQ
1360 1370 1380 1390 1400
ADGSIACDSN GQCPCKSLVV GLKCDTCMQS TFGLSAQNPE GCTRCFCFGR
1410 1420 1430 1440 1450
SGECEQSDLS WGHIRMAESR NLSVQQIRPH SVPSSDYEYI VVVQMEGSSF
1460 1470 1480 1490 1500
HREDAEIQRM NDLSLVPKST GNVSIGAYGQ FYHPLYFQLP PQFYGDRTSS
1510 1520 1530 1540 1550
YGGFLYFTLI TEGAHKPLER NILGQYPLVQ LHAHSKLLLD FYEYEEFEYS
1560 1570 1580 1590 1600
LNVTHRVPLH ESFWKYHHTS QAVDRNTLMA ALQNIRHIFI RAFAFADFQE
1610 1620 1630 1640 1650
VVLQNVHMDA AIYIKGSTNL IAKGVERCKC PKRFDGLSCQ DPGRSFYRWR
1660 1670 1680 1690 1700
NTTIVESVFI EDLIGRAAPC HCNGRSSDCD RETGVCQNCR GNTGGDHCHQ
1710 1720 1730 1740 1750
CAEGFYGDPN SPHGCQACPC PETNRNFARG CNVWDGEVSC VCKPGYTGRL
1760 1770 1780 1790 1800
CERCQAGYFG DPMRYPNTTC QPCNCHPDGI QTEGCDVETG RCYCREGVTG
1810 1820 1830 1840 1850
LKCDKCQAER HHLVDNGCKI CDNCTLLLLD YMELVGNKLR RGMHNMDLTG
1860 1870 1880 1890 1900
IPAPYRKLSE YESAYEKWNG RHWDFSQTKR RLQDYDSADI LKLEAHAENL
1910 1920 1930 1940 1950
KFQSRKAVAT IGKREFAIKS MREDAVTQQH SVGLLRSEIL QTLSDLHGYG
1960 1970 1980 1990 2000
KSAHYLSLPT ALKQARFYLQ AIREHDQMVQ GIRSTNDCAW KHFYAMGNAS
2010 2020 2030 2040 2050
DASFDESGRL EMLWRDLNQT NHRVVDMRLQ VDRVQEVENE AEDVLEHVRN
2060 2070 2080 2090 2100
LSIRVGESHQ ELDELNQRIS DHLDPGYLEQ GEGLLRLTVQ RQIMLNGHLN
2110 2120 2130 2140 2150
QLDGYRILLN TTLGVKTEQQ REVRKHWLPK AEKHASHLLA RSNEYARKFQ
2160 2170 2180 2190 2200
PTRNGARIAM LASSAHSNIT EAINDARLAS ILAKERVYEA QRTLYPSDGS
2210 2220 2230 2240 2250
SMIERAKHSL HRSKQLQQEA LKQMHKSNVL KDKLHRQEQQ VEGIKSTIYD
2260 2270 2280 2290 2300
SGLRTNNISG QLQGLSDGSA RRQAKDSLEM ADRTGEQMRA ELQKAKDMQK
2310 2320 2330 2340 2350
SIQNMRNSFS NLEPDWEIKL GMAQENISLT QTNLRLANVS LSYLEQQAEK
2360 2370 2380 2390 2400
EQQVFEVWNN SMAQQLQQLR DQIAKARHAA EAIDVSLESL GPKCIRSYLP
2410 2420 2430 2440 2450
ASYGLSTSNK IRMSFALSNH LESSPLIHLA SSEGRHITLE LYKRRVRLVW
2460 2470 2480 2490 2500
NLGGTTATVT HPMVVHTRDP KYDDAWYHVE ANRTLNLGSL VVRRMNNYGE
2510 2520 2530 2540 2550
LTPPNPVIIT GSTDTEHTRF YQSRSDRISL GGFASKDLQF TPGLNVVVHQ
2560 2570 2580 2590 2600
VEVDNKPLGL WNFVTSEGSC GGSMVGAKES SASSTARHFN GLGYAQLMKT
2610 2620 2630 2640 2650
RPRPTRKNLF SVQMTFRTLD ENALLFLAVD DKNNRSVSVT LSRGRIMFRI
2660 2670 2680 2690 2700
DYGDESKLEI NTTKKYNVGQ WIKIEAAREF SAKRSTENGM LRVNNDRPIS
2710 2720 2730 2740 2750
GAPTLPVNIH LLPDLSKTVY YLGGVPPGFT SGTSKAPGAD NPFLGCMKDV
2760 2770 2780 2790 2800
QVNGETYDPL ESSSYYGVEP SCKNMITKAG FSGNGYLELP SQSLRKRSNT
2810 2820 2830 2840 2850
ALVFRTLQPD CLLLLAAYPP EILGDYDAKD IKGNFSISLV DGQLHVWVNS
2860 2870 2880 2890 2900
GRSFIKMSSN SSQMNDGEFH VVHLIKTGRK LELMVDDELQ EIRNLNGNPT
2910 2920 2930 2940 2950
VVSLPRDAGG LYIGGAPPHE SYTPLAPTFV NLEGAIRDVV FNNRTINFND
2960 2970 2980 2990 3000
ALTFANVQIG RNGPLMGSLK GGLYDVLLKT EPMIGKSFTA SPEGCKRDFS

C
Length:3,001
Mass (Da):332,741
Last modified:July 24, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEA20B2603771085A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8IP51Q8IP51_DROME
Wing blister, isoform B
wb &agr1, 2, 2]], 2Lan, A1
3,375Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9MRU0M9MRU0_DROME
Wing blister, isoform C
wb &agr1, 2, 2]], 2Lan, A1
2,567Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF53381.3

NCBI Reference Sequences

More...
RefSeqi
NP_476790.3, NM_057442.5

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0305063; FBpp0293600; FBgn0261563

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
43946

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF53381.3
RefSeqiNP_476790.3, NM_057442.5

3D structure databases

SMRiR9PY40
ModBaseiSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0305063; FBpp0293600; FBgn0261563
GeneIDi43946

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
43946
FlyBaseiFBgn0261563, wb

Phylogenomic databases

GeneTreeiENSGT00940000167067
HOGENOMiCLU_000301_0_0_1

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
43946, 0 hits in 3 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
wb, fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
43946

Gene expression databases

BgeeiFBgn0261563, Expressed in embryo and 34 other tissues
ExpressionAtlasiR9PY40, baseline and differential

Family and domain databases

Gene3Di2.60.120.1490, 1 hit
InterProiView protein in InterPro
IPR013320, ConA-like_dom_sf
IPR000742, EGF-like_dom
IPR002049, Laminin_EGF
IPR001791, Laminin_G
IPR000034, Laminin_IV
IPR008211, Laminin_N
IPR038684, Laminin_N_sf
PfamiView protein in Pfam
PF00052, Laminin_B, 2 hits
PF00053, Laminin_EGF, 16 hits
PF02210, Laminin_G_2, 2 hits
PF00055, Laminin_N, 1 hit
SMARTiView protein in SMART
SM00181, EGF, 9 hits
SM00180, EGF_Lam, 17 hits
SM00281, LamB, 2 hits
SM00282, LamG, 3 hits
SM00136, LamNT, 1 hit
SUPFAMiSSF49899, SSF49899, 3 hits
PROSITEiView protein in PROSITE
PS00022, EGF_1, 1 hit
PS01248, EGF_LAM_1, 6 hits
PS50027, EGF_LAM_2, 16 hits
PS50025, LAM_G_DOMAIN, 2 hits
PS51115, LAMININ_IVA, 2 hits
PS51117, LAMININ_NTER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiR9PY40_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: R9PY40
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 24, 2013
Last sequence update: July 24, 2013
Last modified: February 10, 2021
This is version 64 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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