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UniProtKB - R9PY40 (R9PY40_DROME)

Entry version 64 (10 Feb 2021)
Sequence version 1 (24 Jul 2013)
Previous versions | rss
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Protein
Submitted name:

Wing blister, isoform G

Gene

wb

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Wing blister, isoform GImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:wbImported
Synonyms:&agr1Imported, 2Imported, 2]]Imported, 2LanImported, A1Imported, alpha2Imported, alpha[[1Imported, BEST:CK02229Imported, BG:DS03792.1Imported, BG:DS03792.2Imported, CG15288Imported, CG32970Imported, CK02229Imported, CT35236Imported, DLAMImported, Dmel\CG42677Imported, fus5Imported, l(2)09437Imported, l(2)34FbImported, l(2)br1Imported, l34FbImported, LanA1Imported, LM-AImported, WbImported
ORF Names:CG42677Imported, Dmel_CG42677Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2L

Organism-specific databases

Drosophila genome database

More...FlyBasei		FBgn0261563, wb

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Extracellular matrixARBA annotation, Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 24Sequence analysisAdd BLAST24
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500448823725 – 3001Sequence analysisAdd BLAST2977

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi475 ↔ 484PROSITE-ProRule annotation
Disulfide bondi526 ↔ 535PROSITE-ProRule annotation
Disulfide bondi570 ↔ 579PROSITE-ProRule annotation
Disulfide bondi871 ↔ 880PROSITE-ProRule annotation
Disulfide bondi944 ↔ 953PROSITE-ProRule annotation
Disulfide bondi991 ↔ 1000PROSITE-ProRule annotation
Disulfide bondi1018 ↔ 1030PROSITE-ProRule annotation
Disulfide bondi1020 ↔ 1037PROSITE-ProRule annotation
Disulfide bondi1039 ↔ 1048PROSITE-ProRule annotation
Disulfide bondi1087 ↔ 1096PROSITE-ProRule annotation
Disulfide bondi1150 ↔ 1162PROSITE-ProRule annotation
Disulfide bondi1152 ↔ 1169PROSITE-ProRule annotation
Disulfide bondi1171 ↔ 1180PROSITE-ProRule annotation
Disulfide bondi1199 ↔ 1211PROSITE-ProRule annotation
Disulfide bondi1201 ↔ 1218PROSITE-ProRule annotation
Disulfide bondi1220 ↔ 1229PROSITE-ProRule annotation
Disulfide bondi1266 ↔ 1275PROSITE-ProRule annotation
Disulfide bondi1294 ↔ 1306PROSITE-ProRule annotation
Disulfide bondi1296 ↔ 1313PROSITE-ProRule annotation
Disulfide bondi1315 ↔ 1324PROSITE-ProRule annotation
Disulfide bondi1365 ↔ 1374PROSITE-ProRule annotation
Disulfide bondi1689 ↔ 1698PROSITE-ProRule annotation
Disulfide bondi1701 ↔ 1715PROSITE-ProRule annotation
Disulfide bondi1742 ↔ 1751PROSITE-ProRule annotation
Disulfide bondi1773 ↔ 1785PROSITE-ProRule annotation
Disulfide bondi1775 ↔ 1792PROSITE-ProRule annotation
Disulfide bondi1794 ↔ 1803PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationARBA annotation, GlycoproteinARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		FBgn0261563, Expressed in embryo and 34 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		R9PY40, baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		R9PY40

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini149 – 399Laminin N-terminalInterPro annotationAdd BLAST251
Domaini452 – 505Laminin EGF-likeInterPro annotationAdd BLAST54
Domaini506 – 549Laminin EGF-likeInterPro annotationAdd BLAST44
Domaini550 – 599Laminin EGF-likeInterPro annotationAdd BLAST50
Domaini620 – 814Laminin IV type AInterPro annotationAdd BLAST195
Domaini852 – 901Laminin EGF-likeInterPro annotationAdd BLAST50
Domaini902 – 973Laminin EGF-likeInterPro annotationAdd BLAST72
Domaini974 – 1017Laminin EGF-likeInterPro annotationAdd BLAST44
Domaini1018 – 1064Laminin EGF-likeInterPro annotationAdd BLAST47
Domaini1065 – 1109Laminin EGF-likeInterPro annotationAdd BLAST45
Domaini1150 – 1198Laminin EGF-likeInterPro annotationAdd BLAST49
Domaini1199 – 1246Laminin EGF-likeInterPro annotationAdd BLAST48
Domaini1247 – 1293Laminin EGF-likeInterPro annotationAdd BLAST47
Domaini1294 – 1339Laminin EGF-likeInterPro annotationAdd BLAST46
Domaini1340 – 1394Laminin EGF-likeInterPro annotationAdd BLAST55
Domaini1435 – 1627Laminin IV type AInterPro annotationAdd BLAST193
Domaini1670 – 1717Laminin EGF-likeInterPro annotationAdd BLAST48
Domaini1718 – 1772Laminin EGF-likeInterPro annotationAdd BLAST55
Domaini1773 – 1820Laminin EGF-likeInterPro annotationAdd BLAST48
Domaini2584 – 2772LAM_G_DOMAINInterPro annotationAdd BLAST189
Domaini2776 – 2995LAM_G_DOMAINInterPro annotationAdd BLAST220

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni65 – 89DisorderedSequence analysisAdd BLAST25
Regioni106 – 134DisorderedSequence analysisAdd BLAST29

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili2034 – 2068Sequence analysisAdd BLAST35
Coiled coili2278 – 2308Sequence analysisAdd BLAST31
Coiled coili2359 – 2379Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Laminin EGF-like domainPROSITE-ProRule annotationARBA annotation, RepeatARBA annotation, SignalSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00940000167067

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_000301_0_0_1

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.60.120.1490, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR013320, ConA-like_dom_sf
IPR000742, EGF-like_dom
IPR002049, Laminin_EGF
IPR001791, Laminin_G
IPR000034, Laminin_IV
IPR008211, Laminin_N
IPR038684, Laminin_N_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00052, Laminin_B, 2 hits
PF00053, Laminin_EGF, 16 hits
PF02210, Laminin_G_2, 2 hits
PF00055, Laminin_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00181, EGF, 9 hits
SM00180, EGF_Lam, 17 hits
SM00281, LamB, 2 hits
SM00282, LamG, 3 hits
SM00136, LamNT, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF49899, SSF49899, 3 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00022, EGF_1, 1 hit
PS01248, EGF_LAM_1, 6 hits
PS50027, EGF_LAM_2, 16 hits
PS50025, LAM_G_DOMAIN, 2 hits
PS51115, LAMININ_IVA, 2 hits
PS51117, LAMININ_NTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

R9PY40-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQIGNFIKWP LGLILILLVT HCQAKRQRKR LRGFSTAKDL QDYSMPLNDN 
        60         70         80         90        100
STELQQNIVS WTGARIASSP DKKKKSPQSS RRHKTKSGLI IESNIADSES 
       110        120        130        140        150
MLAIASSESV TKKKPPQRRR NGKLQKSGGG AGGGALRLLK TEDVYSSSFS 
       160        170        180        190        200
GGLYPPLFNV VPRAQISVNA TCGQNGAEEY CKQVGAKPCG ICNAHSSDRA 
       210        220        230        240        250
KQRSIQSLIS SGSGSGSGSG FEEGWWQSPT LQGGRQFEYV TILLDLKQTF 
       260        270        280        290        300
QIFSVWLKSA NSPRPASWIL EKSLDGINFE PWQYFGLSDA DCQRRWNLSG 
       310        320        330        340        350
QNGKYVFQND TEIICSTQFS KPGPLENGVL HASLLKNRPG ATDQSPELMK 
       360        370        380        390        400
FITTRYIRIR LQGMHSTANQ DNSLDWLLDS PSLEKHSFYS LSQLKVSARL 
       410        420        430        440        450
DCNGHANRSH ESPDDPLMQC ICQHNTCGAQ CEQCCPLFQD RPYQMGGECE 
       460        470        480        490        500
ICQCYGHAES CTYDPFLDKG ICQSCSNNTA GIECEFCEMG FYRELDAPLT 
       510        520        530        540        550
DPCLPCSCNP ARSTGGCQSD GGSCNCLEGF QGKNCEECAP GYYGDDCKRC 
       560        570        580        590        600
ECDERGSLGS TGSCSGVCQC KLNVEGSTCS ECAPGYFDLS AENAEGCTSC 
       610        620        630        640        650
WCSGVSQTCH SAKLQTLAFE TLNDWKITDI QRVKPISIPV DAETNRLIFA 
       660        670        680        690        700
NELDEVEAIY WQASLGYLGN RLTSYGSRLQ LVLSWDVIRG DRSGKPTTGP 
       710        720        730        740        750
NVILVGKNGL KIAFGDESLD GLGINLNVTL TEVGWYHVPP TVVDIKTRLR 
       760        770        780        790        800
RTEGGDYHGE SVTRSQFLSV LVSLDAVLIR AAFHTDQGET SLERAVIYSG 
       810        820        830        840        850
GVELGGKSSS QVEQCLCPAG YTGLSCEGCA FGFKRIYENT SDHQILSKCI 
       860        870        880        890        900
PCPCNGHSNS CDLQSGNCGD CMHNTFGDRC ERCQLGYYGN PLQGTPNDCK 
       910        920        930        940        950
RCACPLSEDS NNFSPSCQLK SYNYMDLNPQ FELIEHAEYI CTQCPEGYTG 
       960        970        980        990       1000
DHCQVCDDGY FGNPRQPGSS CQRCDCAGGP CNVTTGECIT CRGNTEGWHC 
      1010       1020       1030       1040       1050
ERCKLGYWGD PAVGCDPCHC HTEGSESGLC DSTDGQCLCK PRYAGQKCDE 
      1060       1070       1080       1090       1100
CDVGYANVEL RCPSCNCDPL GSLVQDRCDP HTGQCHCKEG VMGAKCHECQ 
      1110       1120       1130       1140       1150
DGYFGMNAVA YRMDDLAALR QNSDSDDDEW ELVPDTEDPN SESTVACEEC 
      1160       1170       1180       1190       1200
HCSSVGSLSS DCDKRTGQCA CLANVTGRRC DKCRPGHWNL TAGEGCRDCR 
      1210       1220       1230       1240       1250
CDPHGSRGHE CNPWTGQCDC KIGVGGQHCN ECTEGFFGFS TEGCQRCSAC 
      1260       1270       1280       1290       1300
RSEGQVCDPH NGRCICPKFT RGLGCGQCVP GTWGWQARLG CRECECDHIG 
      1310       1320       1330       1340       1350
SIGQQCSTGD GQCQCREGYS GRKCDTCAIG YFGYPECRRC GCDAEGSFTQ 
      1360       1370       1380       1390       1400
ADGSIACDSN GQCPCKSLVV GLKCDTCMQS TFGLSAQNPE GCTRCFCFGR 
      1410       1420       1430       1440       1450
SGECEQSDLS WGHIRMAESR NLSVQQIRPH SVPSSDYEYI VVVQMEGSSF 
      1460       1470       1480       1490       1500
HREDAEIQRM NDLSLVPKST GNVSIGAYGQ FYHPLYFQLP PQFYGDRTSS 
      1510       1520       1530       1540       1550
YGGFLYFTLI TEGAHKPLER NILGQYPLVQ LHAHSKLLLD FYEYEEFEYS 
      1560       1570       1580       1590       1600
LNVTHRVPLH ESFWKYHHTS QAVDRNTLMA ALQNIRHIFI RAFAFADFQE 
      1610       1620       1630       1640       1650
VVLQNVHMDA AIYIKGSTNL IAKGVERCKC PKRFDGLSCQ DPGRSFYRWR 
      1660       1670       1680       1690       1700
NTTIVESVFI EDLIGRAAPC HCNGRSSDCD RETGVCQNCR GNTGGDHCHQ 
      1710       1720       1730       1740       1750
CAEGFYGDPN SPHGCQACPC PETNRNFARG CNVWDGEVSC VCKPGYTGRL 
      1760       1770       1780       1790       1800
CERCQAGYFG DPMRYPNTTC QPCNCHPDGI QTEGCDVETG RCYCREGVTG 
      1810       1820       1830       1840       1850
LKCDKCQAER HHLVDNGCKI CDNCTLLLLD YMELVGNKLR RGMHNMDLTG 
      1860       1870       1880       1890       1900
IPAPYRKLSE YESAYEKWNG RHWDFSQTKR RLQDYDSADI LKLEAHAENL 
      1910       1920       1930       1940       1950
KFQSRKAVAT IGKREFAIKS MREDAVTQQH SVGLLRSEIL QTLSDLHGYG 
      1960       1970       1980       1990       2000
KSAHYLSLPT ALKQARFYLQ AIREHDQMVQ GIRSTNDCAW KHFYAMGNAS 
      2010       2020       2030       2040       2050
DASFDESGRL EMLWRDLNQT NHRVVDMRLQ VDRVQEVENE AEDVLEHVRN 
      2060       2070       2080       2090       2100
LSIRVGESHQ ELDELNQRIS DHLDPGYLEQ GEGLLRLTVQ RQIMLNGHLN 
      2110       2120       2130       2140       2150
QLDGYRILLN TTLGVKTEQQ REVRKHWLPK AEKHASHLLA RSNEYARKFQ 
      2160       2170       2180       2190       2200
PTRNGARIAM LASSAHSNIT EAINDARLAS ILAKERVYEA QRTLYPSDGS 
      2210       2220       2230       2240       2250
SMIERAKHSL HRSKQLQQEA LKQMHKSNVL KDKLHRQEQQ VEGIKSTIYD 
      2260       2270       2280       2290       2300
SGLRTNNISG QLQGLSDGSA RRQAKDSLEM ADRTGEQMRA ELQKAKDMQK 
      2310       2320       2330       2340       2350
SIQNMRNSFS NLEPDWEIKL GMAQENISLT QTNLRLANVS LSYLEQQAEK 
      2360       2370       2380       2390       2400
EQQVFEVWNN SMAQQLQQLR DQIAKARHAA EAIDVSLESL GPKCIRSYLP 
      2410       2420       2430       2440       2450
ASYGLSTSNK IRMSFALSNH LESSPLIHLA SSEGRHITLE LYKRRVRLVW 
      2460       2470       2480       2490       2500
NLGGTTATVT HPMVVHTRDP KYDDAWYHVE ANRTLNLGSL VVRRMNNYGE 
      2510       2520       2530       2540       2550
LTPPNPVIIT GSTDTEHTRF YQSRSDRISL GGFASKDLQF TPGLNVVVHQ 
      2560       2570       2580       2590       2600
VEVDNKPLGL WNFVTSEGSC GGSMVGAKES SASSTARHFN GLGYAQLMKT 
      2610       2620       2630       2640       2650
RPRPTRKNLF SVQMTFRTLD ENALLFLAVD DKNNRSVSVT LSRGRIMFRI 
      2660       2670       2680       2690       2700
DYGDESKLEI NTTKKYNVGQ WIKIEAAREF SAKRSTENGM LRVNNDRPIS 
      2710       2720       2730       2740       2750
GAPTLPVNIH LLPDLSKTVY YLGGVPPGFT SGTSKAPGAD NPFLGCMKDV 
      2760       2770       2780       2790       2800
QVNGETYDPL ESSSYYGVEP SCKNMITKAG FSGNGYLELP SQSLRKRSNT 
      2810       2820       2830       2840       2850
ALVFRTLQPD CLLLLAAYPP EILGDYDAKD IKGNFSISLV DGQLHVWVNS 
      2860       2870       2880       2890       2900
GRSFIKMSSN SSQMNDGEFH VVHLIKTGRK LELMVDDELQ EIRNLNGNPT 
      2910       2920       2930       2940       2950
VVSLPRDAGG LYIGGAPPHE SYTPLAPTFV NLEGAIRDVV FNNRTINFND 
      2960       2970       2980       2990       3000
ALTFANVQIG RNGPLMGSLK GGLYDVLLKT EPMIGKSFTA SPEGCKRDFS 

C
Length:3,001
Mass (Da):332,741
Last modified:July 24, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEA20B2603771085A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8IP51Q8IP51_DROME
Wing blister, isoform B
wb &agr1, 2, 2]], 2Lan, A1
3,375Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9MRU0M9MRU0_DROME
Wing blister, isoform C
wb &agr1, 2, 2]], 2Lan, A1
2,567Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF53381.3

NCBI Reference Sequences

More...RefSeqi		NP_476790.3, NM_057442.5

Genome annotation databases

Ensembl metazoan genome annotation project

More...EnsemblMetazoai		FBtr0305063; FBpp0293600; FBgn0261563

Database of genes from NCBI RefSeq genomes

More...GeneIDi		43946

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF53381.3
RefSeqiNP_476790.3, NM_057442.5

3D structure databases

SMRiR9PY40
ModBaseiSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0305063; FBpp0293600; FBgn0261563
GeneIDi43946

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		43946
FlyBaseiFBgn0261563, wb

Phylogenomic databases

GeneTreeiENSGT00940000167067
HOGENOMiCLU_000301_0_0_1

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		43946, 0 hits in 3 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		wb, fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		43946

Gene expression databases

BgeeiFBgn0261563, Expressed in embryo and 34 other tissues
ExpressionAtlasiR9PY40, baseline and differential

Family and domain databases

Gene3Di2.60.120.1490, 1 hit
InterProiView protein in InterPro
IPR013320, ConA-like_dom_sf
IPR000742, EGF-like_dom
IPR002049, Laminin_EGF
IPR001791, Laminin_G
IPR000034, Laminin_IV
IPR008211, Laminin_N
IPR038684, Laminin_N_sf
PfamiView protein in Pfam
PF00052, Laminin_B, 2 hits
PF00053, Laminin_EGF, 16 hits
PF02210, Laminin_G_2, 2 hits
PF00055, Laminin_N, 1 hit
SMARTiView protein in SMART
SM00181, EGF, 9 hits
SM00180, EGF_Lam, 17 hits
SM00281, LamB, 2 hits
SM00282, LamG, 3 hits
SM00136, LamNT, 1 hit
SUPFAMiSSF49899, SSF49899, 3 hits
PROSITEiView protein in PROSITE
PS00022, EGF_1, 1 hit
PS01248, EGF_LAM_1, 6 hits
PS50027, EGF_LAM_2, 16 hits
PS50025, LAM_G_DOMAIN, 2 hits
PS51115, LAMININ_IVA, 2 hits
PS51117, LAMININ_NTER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiR9PY40_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: R9PY40
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 24, 2013
Last sequence update: July 24, 2013
Last modified: February 10, 2021
This is version 64 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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