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Entry version 27 (10 Feb 2021)
Sequence version 1 (24 Jul 2013)
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Protein

CCDC66 domain-containing protein

Gene

CAPTEDRAFT_217825

Organism
Capitella teleta (Polychaete worm)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
CCDC66 domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:CAPTEDRAFT_217825Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCapitella teleta (Polychaete worm)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri283909 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaSpiraliaLophotrochozoaAnnelidaPolychaetaSedentariaScolecidaCapitellidaeCapitella
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000014760 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini470 – 604CCDC66InterPro annotationAdd BLAST135

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni58 – 125DisorderedSequence analysisAdd BLAST68
Regioni145 – 396DisorderedSequence analysisAdd BLAST252
Regioni410 – 592DisorderedSequence analysisAdd BLAST183
Regioni621 – 788DisorderedSequence analysisAdd BLAST168
Regioni800 – 826DisorderedSequence analysisAdd BLAST27

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi98 – 125PolarSequence analysisAdd BLAST28
Compositional biasi149 – 169PolyampholyteSequence analysisAdd BLAST21
Compositional biasi170 – 189PolarSequence analysisAdd BLAST20
Compositional biasi205 – 220PolyampholyteSequence analysisAdd BLAST16
Compositional biasi229 – 249PolyampholyteSequence analysisAdd BLAST21
Compositional biasi410 – 439PolyampholyteSequence analysisAdd BLAST30
Compositional biasi465 – 486PolarSequence analysisAdd BLAST22
Compositional biasi497 – 592PolyampholyteSequence analysisAdd BLAST96
Compositional biasi638 – 656PolarSequence analysisAdd BLAST19
Compositional biasi676 – 713PolyampholyteSequence analysisAdd BLAST38
Compositional biasi727 – 750PolyampholyteSequence analysisAdd BLAST24
Compositional biasi762 – 786PolyampholyteSequence analysisAdd BLAST25

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_010332_0_0_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
KNSNYER

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039183, CCD66
IPR040467, CCDC66_dom

The PANTHER Classification System

More...
PANTHERi
PTHR22736, PTHR22736, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15236, CCDC66, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

R7TN75-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSDSPLIVPA TCPRHSYANS YATSAALTYS TSSTTFATSS VGGKPLIFWD
60 70 80 90 100
QQAQNAKNAK KKFGYKSKEL QHPLRSRNMP EPQAPPPQRG RRKPANQKKA
110 120 130 140 150
NPVSNGNGRT TSKKPESAVD PNSVTLTQKE FDTILETIGH LAIETENLKS
160 170 180 190 200
PRQGEELHED PKPKTTNSRG DAQEETIFNL ASQPNKPDTS HDIPPKALEK
210 220 230 240 250
PPIAPQNRHN ERRNEPEKQT PKPEPAPNFL SKAERKRLQW EKERAQQSEE
260 270 280 290 300
WNPWGRPGCG APVKDREGNT LTDYSIRQDR NEILSEPFED GGKLSINQKS
310 320 330 340 350
VLLQEEMQKL GITPSPRQPK TPVANPSTSA FEYSKDDPLL PHQRAALQAR
360 370 380 390 400
EPQPPPAVAS QRQPPPSTQR QKSEEPAAIR SSFVVGNGTP DDDRFVSAKE
410 420 430 440 450
RKRLLWLQEL EQQREEDRQR KAKEKSYGRQ DEETHWADKF SNYQPKGLPA
460 470 480 490 500
QDSIAPPPPN DTAARISSAP VQTMDSTSNK LEDATYLRGQ NTRIDPVTLR
510 520 530 540 550
ELEDKRKKEQ QHQDFIRQQI EEKARLKREE RERRVREELE EEKQLQKERT
560 570 580 590 600
HGLTHREDAK QKEKDEAERK RALEEAIERA QEAAEMDKHQ KRLLKLQQGG
610 620 630 640 650
HDVSNFETKT PRNMLPAQFN TGTIVEPSHV PGLDSSPRDV ETRNQGCYTE
660 670 680 690 700
NRVLTPTDQR TARKEFGVQT ESDITLGNRE ETDIEYQGPF SKKVRIKSGP
710 720 730 740 750
KDGRPKKPVK INERPKWGYQ NAAKKKAVKQ SARDPHYEQK KQRAEIMKQE
760 770 780 790 800
RQQAMLKMQQ EQRRTVTRET AASRSRSHEP KSPMIPKHQD YDQYARQNLK
810 820 830 840 850
DTSHKSQTPP PSVPTKHRSP SPPVPTIKHM IRECDDQYKQ TSSRVGGSKY
860 870 880 890 900
ADMDPTYNNS DFIPFVRTTD LLDPSKADES VPVSREQSAV QRGRKVYQQE
910 920 930 940 950
LNPAKYGKKM ANIKDKNESY TKDPILQPNL VTEHPTSRQG QILQQLSSLR
960 970
RGLMLKQREL EMNDGALGLA
Length:970
Mass (Da):110,617
Last modified:July 24, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDAAA1D58411E59A9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AMQN01012050 Genomic DNA No translation available.
KB309260 Genomic DNA Translation: ELT94987.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
CapteT217825; CapteP217825; CapteG217825

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AMQN01012050 Genomic DNA No translation available.
KB309260 Genomic DNA Translation: ELT94987.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblMetazoaiCapteT217825; CapteP217825; CapteG217825

Phylogenomic databases

HOGENOMiCLU_010332_0_0_1
OMAiKNSNYER

Family and domain databases

InterProiView protein in InterPro
IPR039183, CCD66
IPR040467, CCDC66_dom
PANTHERiPTHR22736, PTHR22736, 1 hit
PfamiView protein in Pfam
PF15236, CCDC66, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiR7TN75_CAPTE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: R7TN75
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 24, 2013
Last sequence update: July 24, 2013
Last modified: February 10, 2021
This is version 27 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteomeImported
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