Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

SH2B adapter protein 3

Gene

SH2B3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
SH2B adapter protein 3Imported
Gene namesi
Name:SH2B3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000111252.10
HGNCiHGNC:29605 SH2B3

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000111252

PTM / Processingi

Proteomic databases

PeptideAtlasiR4GN84
PRIDEiR4GN84

Expressioni

Gene expression databases

BgeeiENSG00000111252 Expressed in 213 organ(s), highest expression level in leukocyte
ExpressionAtlasiR4GN84 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliR4GN84
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000063355

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR011993 PH-like_dom_sf
IPR030523 SH2B
IPR030522 SH2B3
PANTHERiPTHR10872 PTHR10872, 1 hit
PTHR10872:SF1 PTHR10872:SF1, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

R4GN84-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XQFTDLFQRY FCREVRDGRA PGRDYRDTGR GPPAKAEASP EPGPGPAAPG
60 70 80 90 100
LPKARSSEEL APPRPPGPCS FQHFRRSLRH IFRRRSAGEL PAAHTAAAPG
110 120 130 140 150
TPGEAAETPA RPGLAKKFLP WSLAREPPPE ALKEAVLRYS LADEASMDSG
160 170 180 190 200
ARWQRGRLAL RRAPGPDGPD RVLELFDPPK WPEPELSRLR FRLKQGLSCA
210
HVPTRCNLAG ASGIGH
Length:216
Mass (Da):23,567
Last modified:October 5, 2016 - v8
Checksum:i2030F3920F2F17EE
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9UQQ2SH2B3_HUMAN
SH2B adapter protein 3
SH2B3 LNK
575Annotation score:
F5GYM4F5GYM4_HUMAN
SH2B adapter protein 3
SH2B3
373Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei216Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002395 Genomic DNA No translation available.
AC005805 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000550925; ENSP00000473529; ENSG00000111252
UCSCiuc058tgy.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002395 Genomic DNA No translation available.
AC005805 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliR4GN84
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiR4GN84
PRIDEiR4GN84

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000550925; ENSP00000473529; ENSG00000111252
UCSCiuc058tgy.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000111252.10
HGNCiHGNC:29605 SH2B3
OpenTargetsiENSG00000111252
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00530000063355

Miscellaneous databases

ChiTaRSiSH2B3 human

Gene expression databases

BgeeiENSG00000111252 Expressed in 213 organ(s), highest expression level in leukocyte
ExpressionAtlasiR4GN84 baseline and differential

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR011993 PH-like_dom_sf
IPR030523 SH2B
IPR030522 SH2B3
PANTHERiPTHR10872 PTHR10872, 1 hit
PTHR10872:SF1 PTHR10872:SF1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiR4GN84_HUMAN
AccessioniPrimary (citable) accession number: R4GN84
Entry historyiIntegrated into UniProtKB/TrEMBL: June 26, 2013
Last sequence update: October 5, 2016
Last modified: September 12, 2018
This is version 43 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again