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Protein
Submitted name:

Pleckstrin homology domain-containing family A member 1

Gene

PLEKHA1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Pleckstrin homology domain-containing family A member 1Imported
Gene namesi
Name:PLEKHA1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000107679.14
HGNCiHGNC:14335 PLEKHA1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000107679

PTM / Processingi

Proteomic databases

MaxQBiR4GMZ9
PeptideAtlasiR4GMZ9
PRIDEiR4GMZ9

Expressioni

Gene expression databases

BgeeiENSG00000107679 Expressed in 224 organ(s), highest expression level in chorionic villus
ExpressionAtlasiR4GMZ9 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliR4GMZ9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 112PHInterPro annotationAdd BLAST106

Phylogenomic databases

eggNOGiENOG410IF2M Eukaryota
ENOG410ZQEQ LUCA
GeneTreeiENSGT00440000037398

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
PfamiView protein in Pfam
PF00169 PH, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
PROSITEiView protein in PROSITE
PS50003 PH_DOMAIN, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

R4GMZ9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPYVDRQNRI CGFLDIEENE NSGKFLRRYF ILDTREDSFV WYMDNPQNLP
60 70 80 90 100
SGSSRVGAIK LTYISKVSDA TKLRPKAEFC FVMNAGMRKY FLQANDQQDL
110 120 130
VEWVNVLNKA IKITVPKQSD SQPNSDNLSR HGE
Length:133
Mass (Da):15,400
Last modified:June 26, 2013 - v1
Checksum:i30C4564330A8BB13
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9HB21PKHA1_HUMAN
Pleckstrin homology domain-containi...
PLEKHA1 TAPP1
404Annotation score:
Q5RGS4Q5RGS4_HUMAN
Pleckstrin homology domain-containi...
PLEKHA1
383Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei133Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX664700 Genomic DNA No translation available.
BX842242 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000463663; ENSP00000473424; ENSG00000107679
UCSCiuc057wnj.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX664700 Genomic DNA No translation available.
BX842242 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliR4GMZ9
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiR4GMZ9
PeptideAtlasiR4GMZ9
PRIDEiR4GMZ9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000463663; ENSP00000473424; ENSG00000107679
UCSCiuc057wnj.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000107679.14
HGNCiHGNC:14335 PLEKHA1
OpenTargetsiENSG00000107679
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IF2M Eukaryota
ENOG410ZQEQ LUCA
GeneTreeiENSGT00440000037398

Miscellaneous databases

ChiTaRSiPLEKHA1 human

Gene expression databases

BgeeiENSG00000107679 Expressed in 224 organ(s), highest expression level in chorionic villus
ExpressionAtlasiR4GMZ9 baseline and differential

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
PfamiView protein in Pfam
PF00169 PH, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
PROSITEiView protein in PROSITE
PS50003 PH_DOMAIN, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiR4GMZ9_HUMAN
AccessioniPrimary (citable) accession number: R4GMZ9
Entry historyiIntegrated into UniProtKB/TrEMBL: June 26, 2013
Last sequence update: June 26, 2013
Last modified: September 12, 2018
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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