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Entry version 46 (18 Sep 2019)
Sequence version 2 (07 Jun 2017)
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Protein
Submitted name:

BIVM-ERCC5 readthrough

Gene

BIVM-ERCC5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
BIVM-ERCC5 readthroughImported
Submitted name:
DNA repair protein-complementing XP-G cellsImported
Submitted name:
ERCC5-202 proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BIVM-ERCC5Imported
Synonyms:ERCC5Imported, ERCC5-202Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 13

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:43690 BIVM-ERCC5
HGNC:3437 ERCC5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

NucleusSAAS annotation

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000134899

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
BIVM-ERCC5

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
R4GMW8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000270181 Expressed in 89 organ(s), highest expression level in heart

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000473384

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini469 – 552XPGNInterPro annotationAdd BLAST84
Domaini1231 – 1300XPGIInterPro annotationAdd BLAST70

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 33DisorderedSequence analysisAdd BLAST33
Regioni152 – 184DisorderedSequence analysisAdd BLAST33
Regioni438 – 461DisorderedSequence analysisAdd BLAST24
Regioni760 – 796DisorderedSequence analysisAdd BLAST37
Regioni808 – 839DisorderedSequence analysisAdd BLAST32
Regioni858 – 927DisorderedSequence analysisAdd BLAST70
Regioni964 – 987DisorderedSequence analysisAdd BLAST24
Regioni1121 – 1178DisorderedSequence analysisAdd BLAST58
Regioni1510 – 1535DisorderedSequence analysisAdd BLAST26
Regioni1549 – 1640DisorderedSequence analysisAdd BLAST92

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1187 – 1210Sequence analysisAdd BLAST24

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi11 – 28PolyampholyteSequence analysisAdd BLAST18
Compositional biasi438 – 452PolarSequence analysisAdd BLAST15
Compositional biasi897 – 912PolarSequence analysisAdd BLAST16
Compositional biasi1130 – 1178PolyampholyteSequence analysisAdd BLAST49
Compositional biasi1549 – 1604PolarSequence analysisAdd BLAST56
Compositional biasi1622 – 1640BasicSequence analysisAdd BLAST19

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2520 Eukaryota
COG0258 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00510000048601

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036279 5-3_exonuclease_C_sf
IPR008918 HhH2
IPR029060 PIN-like_dom_sf
IPR006086 XPG-I_dom
IPR006084 XPG/Rad2
IPR001044 XPG/Rad2_eukaryotes
IPR019974 XPG_CS
IPR006085 XPG_DNA_repair_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00867 XPG_I, 1 hit
PF00752 XPG_N, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00853 XPGRADSUPER
PR00066 XRODRMPGMNTG

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00279 HhH2, 1 hit
SM00484 XPGI, 1 hit
SM00485 XPGN, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47807 SSF47807, 1 hit
SSF88723 SSF88723, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00600 rad2, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00841 XPG_1, 1 hit
PS00842 XPG_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

R4GMW8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPNVAETERS NDSGNGEHKS ERKSPEENLQ GAVKSFCTSA SGAPLGPKGD
60 70 80 90 100
GHYPWSCPVT HTREKIYAIC SDYAFLNQAT SIYKTPNPSR SPCLPDSTSL
110 120 130 140 150
SAGNNSSRYI GIPTSTSEII YNEENSLENL SNSLGKLPLA WEIDKSEFDG
160 170 180 190 200
VTTNSKHKSG NAKKQVSKRK TSDKKGRYQK ECPQHSPLED IKQRKVLDLR
210 220 230 240 250
RWYCISRPQY KTSCGISSLI SCWNFLYSTM GAGNLPPITQ EEALHILGFQ
260 270 280 290 300
PPFEDIRFGP FTGNTTLMRW FRQINDHFHV KGCSYVLYKP HGKNKTAGET
310 320 330 340 350
ASGALSKLTR GLKDESLAYI YHCQNHYFCP IGFEATPVKA NKAFSRGPLS
360 370 380 390 400
PQEVEYWILI GESSRKHPAI HCKKWADIVT DLNTQNPEYL DIRHLERGLQ
410 420 430 440 450
YRKTKKVGGN LHCIIAFQRL NWQRFGLWNF PFGTIRQESQ PPTHAQGIAK
460 470 480 490 500
SESEDNISKK QHGRLGRSFS ASFHQDSAWK KMSNISIWLN QALKGVRDRH
510 520 530 540 550
GNSIENPHLL TLFHRLCKLL FFRIRPIFVF DGDAPLLKKQ TLVKRRQRKD
560 570 580 590 600
LASSDSRKTT EKLLKTFLKR QAIKTAFRSK RDEALPSLTQ VRRENDLYVL
610 620 630 640 650
PPLQEEEKHS SEEEDEKEWQ ERMNQKQALQ EEFFHNPQAI DIESEDFSSL
660 670 680 690 700
PPEVKHEILT DMKEFTKRRR TLFEAMPEES DDFSQYQLKG LLKKNYLNQH
710 720 730 740 750
IEHVQKEMNQ QHSGHIRRQY EDEGGFLKEV ESRRVVSEDT SHYILIKGIQ
760 770 780 790 800
AKTVAEVDSE SLPSSSKMHG MSFDVKSSPC EKLKTEKEPD ATPPSPRTLL
810 820 830 840 850
AMQAALLGSS SEEELESENR RQARGRNAPA AVDEGSISPR TLSAIKRALD
860 870 880 890 900
DDEDVKVCAG DDVQTGGPGA EEMRINSSTE NSDEGLKVRD GKGIPFTATL
910 920 930 940 950
ASSSVNSAEE HVASTNEGRE PTDSVPKEQM SLVHVGTEAF PISDESMIKD
960 970 980 990 1000
RKDRLPLESA VVRHSDAPGL PNGRELTPAS PTCTNSVSKN ETHAEVLEQQ
1010 1020 1030 1040 1050
NELCPYESKF DSSLLSSDDE TKCKPNSASE VIGPVSLQET SSIVSVPSEA
1060 1070 1080 1090 1100
VDNVENVVSF NAKEHENFLE TIQEQQTTES AGQDLISIPK AVEPMEIDSE
1110 1120 1130 1140 1150
ESESDGSFIE VQSVISDEEL QAEFPETSKP PSEQGEEELV GTREGEAPAE
1160 1170 1180 1190 1200
SESLLRDNSE RDDVDGEPQE AEKDAEDSLH EWQDINLEEL ETLESNLLAQ
1210 1220 1230 1240 1250
QNSLKAQKQQ QERIAATVTG QMFLESQELL RLFGIPYIQA PMEAEAQCAI
1260 1270 1280 1290 1300
LDLTDQTSGT ITDDSDIWLF GARHVYRNFF NKNKFVEYYQ YVDFHNQLGL
1310 1320 1330 1340 1350
DRNKLINLAY LLGSDYTEGI PTVGCVTAME ILNEFPGHGL EPLLKFSEWW
1360 1370 1380 1390 1400
HEAQKNPKIR PNPHDTKVKK KLRTLQLTPG FPNPAVAEAY LKPVVDDSKG
1410 1420 1430 1440 1450
SFLWGKPDLD KIREFCQRYF GWNRTKTDES LFPVLKQLDA QQTQLRIDSF
1460 1470 1480 1490 1500
FRLAQQEKED AKRIKSQRLN RAVTCMLRKE KEAAASEIEA VSVAMEKEFE
1510 1520 1530 1540 1550
LLDKAKGKTQ KRGITNTLEE SSSLKRKRLS DSKGKNTCGG FLGETCLSES
1560 1570 1580 1590 1600
SDGSSSEDAE SSSLMNVQRR TAAKEPKTSA SDSQNSVKEA PVKNGGATTS
1610 1620 1630 1640
SSSDSDDDGG KEKMVLVTAR SVFGKKRRKL RRARGRKRKT
Length:1,640
Mass (Da):184,453
Last modified:June 7, 2017 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4583E676FDE637D6
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P28715ERCC5_HUMAN
DNA repair protein complementing XP...
ERCC5 ERCM2, XPG, XPGC
1,186Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A090HNM7A0A090HNM7_HUMAN
DNA repair protein-complementing XP...
ERCC5 ERCC5-201
1,018Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1W2PS85A0A1W2PS85_HUMAN
BIVM-ERCC5 readthrough
BIVM-ERCC5
1,411Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A494C0S2A0A494C0S2_HUMAN
DNA repair protein-complementing XP...
ERCC5
904Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A494C113A0A494C113_HUMAN
DNA repair protein-complementing XP...
ERCC5
127Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F2Z2A1F2Z2A1_HUMAN
DNA repair protein-complementing XP...
ERCC5
43Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1W2PRR4A0A1W2PRR4_HUMAN
BIVM-ERCC5 readthrough
BIVM-ERCC5
133Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1W2PRU8A0A1W2PRU8_HUMAN
BIVM-ERCC5 readthrough
BIVM-ERCC5
145Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL157769 Genomic DNA No translation available.
LM994822 mRNA Translation: CDY80175.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000602836; ENSP00000473384; ENSG00000134899
ENST00000639435; ENSP00000491742; ENSG00000270181

UCSC genome browser

More...
UCSCi
uc058ycp.1 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL157769 Genomic DNA No translation available.
LM994822 mRNA Translation: CDY80175.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9606.ENSP00000473384

Polymorphism and mutation databases

BioMutaiBIVM-ERCC5

Proteomic databases

PRIDEiR4GMW8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000602836; ENSP00000473384; ENSG00000134899
ENST00000639435; ENSP00000491742; ENSG00000270181
UCSCiuc058ycp.1 human

Organism-specific databases

GeneCards: human genes, protein and diseases

More...
GeneCardsi
BIVM-ERCC5
HGNCiHGNC:43690 BIVM-ERCC5
HGNC:3437 ERCC5
OpenTargetsiENSG00000134899

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG2520 Eukaryota
COG0258 LUCA
GeneTreeiENSGT00510000048601

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
BIVM-ERCC5 human

Gene expression databases

BgeeiENSG00000270181 Expressed in 89 organ(s), highest expression level in heart

Family and domain databases

InterProiView protein in InterPro
IPR036279 5-3_exonuclease_C_sf
IPR008918 HhH2
IPR029060 PIN-like_dom_sf
IPR006086 XPG-I_dom
IPR006084 XPG/Rad2
IPR001044 XPG/Rad2_eukaryotes
IPR019974 XPG_CS
IPR006085 XPG_DNA_repair_N
PfamiView protein in Pfam
PF00867 XPG_I, 1 hit
PF00752 XPG_N, 1 hit
PRINTSiPR00853 XPGRADSUPER
PR00066 XRODRMPGMNTG
SMARTiView protein in SMART
SM00279 HhH2, 1 hit
SM00484 XPGI, 1 hit
SM00485 XPGN, 1 hit
SUPFAMiSSF47807 SSF47807, 1 hit
SSF88723 SSF88723, 1 hit
TIGRFAMsiTIGR00600 rad2, 1 hit
PROSITEiView protein in PROSITE
PS00841 XPG_1, 1 hit
PS00842 XPG_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiR4GMW8_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: R4GMW8
Secondary accession number(s): A0A090J7P6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 26, 2013
Last sequence update: June 7, 2017
Last modified: September 18, 2019
This is version 46 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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