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Protein
Submitted name:

NT-3 growth factor receptor

Gene

NTRK3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
NT-3 growth factor receptorImported
Gene namesi
Name:NTRK3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

EuPathDBiHostDB:ENSG00000140538.16
HGNCiHGNC:8033 NTRK3

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000140538

PTM / Processingi

Proteomic databases

PeptideAtlasiR4GMR8

Expressioni

Gene expression databases

BgeeiENSG00000140538 Expressed in 199 organ(s), highest expression level in primary visual cortex
ExpressionAtlasiR4GMR8 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliR4GMR8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 146Protein kinaseInterPro annotationAdd BLAST146

Phylogenomic databases

GeneTreeiENSGT00760000118818

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR001245 Ser-Thr/Tyr_kinase_cat_dom
IPR008266 Tyr_kinase_AS
IPR020635 Tyr_kinase_cat_dom
IPR002011 Tyr_kinase_rcpt_2_CS
PfamiView protein in Pfam
PF07714 Pkinase_Tyr, 1 hit
PRINTSiPR00109 TYRKINASE
SMARTiView protein in SMART
SM00219 TyrKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00109 PROTEIN_KINASE_TYR, 1 hit
PS00239 RECEPTOR_TYR_KIN_II, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

R4GMR8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XGVCGDGDPL IMVFEYMKHG DLNKFLRAHG PDAMILVDGQ PRQAKGELGL
60 70 80 90 100
SQMLHIASQI ASGMVYLASQ HFVHRDLATR NCLVGANLLV KIGDFGMSRD
110 120 130 140
VYSTDYYRYT SAKALEECSD LSDRENTVKD SLYELIPPDR LCRHED
Length:146
Mass (Da):16,321
Last modified:June 26, 2013 - v1
Checksum:i15A048E80FD55196
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q16288NTRK3_HUMAN
NT-3 growth factor receptor
NTRK3 TRKC
839Annotation score:
H0YM90H0YM90_HUMAN
Tyrosine-protein kinase receptor
NTRK3
705Annotation score:
A0A0D9SFP6A0A0D9SFP6_HUMAN
Tyrosine-protein kinase receptor
NTRK3
864Annotation score:
B7Z7U4B7Z7U4_HUMAN
Tyrosine-protein kinase receptor
NTRK3
617Annotation score:
R4GN40R4GN40_HUMAN
NT-3 growth factor receptor
NTRK3
85Annotation score:
R4GNH5R4GNH5_HUMAN
NT-3 growth factor receptor
NTRK3
90Annotation score:
A0A087WX31A0A087WX31_HUMAN
NT-3 growth factor receptor
NTRK3
49Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009711 Genomic DNA No translation available.
AC011966 Genomic DNA No translation available.
AC021677 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000558576; ENSP00000473315; ENSG00000140538
UCSCiuc059mwe.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009711 Genomic DNA No translation available.
AC011966 Genomic DNA No translation available.
AC021677 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliR4GMR8
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiR4GMR8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000558576; ENSP00000473315; ENSG00000140538
UCSCiuc059mwe.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000140538.16
HGNCiHGNC:8033 NTRK3
OpenTargetsiENSG00000140538
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000118818

Miscellaneous databases

ChiTaRSiNTRK3 human

Gene expression databases

BgeeiENSG00000140538 Expressed in 199 organ(s), highest expression level in primary visual cortex
ExpressionAtlasiR4GMR8 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR001245 Ser-Thr/Tyr_kinase_cat_dom
IPR008266 Tyr_kinase_AS
IPR020635 Tyr_kinase_cat_dom
IPR002011 Tyr_kinase_rcpt_2_CS
PfamiView protein in Pfam
PF07714 Pkinase_Tyr, 1 hit
PRINTSiPR00109 TYRKINASE
SMARTiView protein in SMART
SM00219 TyrKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00109 PROTEIN_KINASE_TYR, 1 hit
PS00239 RECEPTOR_TYR_KIN_II, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiR4GMR8_HUMAN
AccessioniPrimary (citable) accession number: R4GMR8
Entry historyiIntegrated into UniProtKB/TrEMBL: June 26, 2013
Last sequence update: June 26, 2013
Last modified: September 12, 2018
This is version 21 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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