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Protein
Submitted name:

Leucine rich repeat containing 8 VRAC subunit A

Gene

LRRC8A

Organism
Anas platyrhynchos (Mallard) (Anas boschas)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Leucine rich repeat containing 8 VRAC subunit AImported
Submitted name:
Leucine-rich repeat-containing protein 8AImported
Gene namesi
Name:LRRC8AImported
ORF Names:Anapl_00525Imported
OrganismiAnas platyrhynchos (Mallard) (Anas boschas)Imported
Taxonomic identifieri8839 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeAnseriformesAnatidaeAnatinaeAnas
Proteomesi
  • UP000016666 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei27 – 45HelicalSequence analysisAdd BLAST19
Transmembranei124 – 144HelicalSequence analysisAdd BLAST21
Transmembranei268 – 286HelicalSequence analysisAdd BLAST19
Transmembranei322 – 344HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 340Pannexin_likeInterPro annotationAdd BLAST340

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00920000148937
KOiK22038
OMAiVDTQPAY
OrthoDBiEOG091G01ER

Family and domain databases

Gene3Di3.80.10.10, 2 hits
InterProiView protein in InterPro
IPR001611 Leu-rich_rpt
IPR003591 Leu-rich_rpt_typical-subtyp
IPR032675 LRR_dom_sf
IPR038960 LRRC8
IPR021040 LRRC8_Pannexin-like
PANTHERiPTHR43945 PTHR43945, 1 hit
PfamiView protein in Pfam
PF13855 LRR_8, 3 hits
PF12534 Pannexin_like, 1 hit
SMARTiView protein in SMART
SM00369 LRR_TYP, 8 hits
PROSITEiView protein in PROSITE
PS51450 LRR, 12 hits

Sequencei

Sequence statusi: Fragment.

R0K7Z6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIPVTELRYF ADTQPAYRIL KPWWDVFTDY ISIVMLMIAV FGGTLQVTQD
60 70 80 90 100
KMICLPCKWV TKDSCNDSVR GWTAAAPERT YFNSSLVPSA DTGPTGIRYD
110 120 130 140 150
LDRHQYNYVD AVCYENRLHW FAKYFPYLVL LHTLIFLACS NFWFKFPRTS
160 170 180 190 200
SKLEHFVSIL LKCFDSPWTT RALSETVVEE SDTKPAFGKM NGSMDKKSST
210 220 230 240 250
VSEDVEATVP MLQRTKSRIE QGIVDRSETG VLDKKEGEQA KALFEKVKKF
260 270 280 290 300
RTHVEEGDIV YRLYMRQTII KVIKFILIIC YTVYYVNNIT FDVDCKVDIE
310 320 330 340 350
SLTGYRMYRC AHPLATLFKI LASFYISLVI VYGLICMYTL WWMLRRSLKK
360 370 380 390 400
YSFESIREES SYSDIPDVKN DFAFMLHLID QYDPLYSKRF AVFLSEVSEN
410 420 430 440 450
KLRQLNLNNE WTLEKLRQRI TKNSQDKLEL HLFMLSGIPD TVFDLIELEV
460 470 480 490 500
LKLELIPDVT IPPSIAQLTS LKELWLYHTA AKIEAPALAF LRENLKSLHI
510 520 530 540 550
KFTDIKEIPL WIYSLKTLEE LHLTGNLSAE NNRYIVIDGL RELKRLKVLR
560 570 580 590 600
LKSNLTKLPQ VVTDVGVHLQ KLSINNEGTK LIVLNSLKKM VNLTELELIR
610 620 630 640 650
CDLERIPHSI FSLHNLQEID LKDNNLKTIE EIISFQHLHR LTCLKLWYNH
660 670 680 690 700
IAYIPMQIGN LTNLERLYLN RNKIEKIPTQ LFYCRKLRYL DLSHNNLTFI
710 720 730 740 750
PPDIGLLQNL QNLAVTANRI ESLPPELFQC RKLRTLNLGN NVLQSLPSRV
760 770 780 790 800
GELTNLSQIE LRGNRLECLP VELGECPLLK RSGLVVEEDL FNTLPLEVKE
810
RLWRADKEQA
Length:810
Mass (Da):94,300
Last modified:June 26, 2013 - v1
Checksum:i49F56F91153DEEC5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei810Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ADON01030700 Genomic DNA No translation available.
KB742651 Genomic DNA Translation: EOB05907.1
RefSeqiXP_005013252.1, XM_005013195.2
XP_005013254.1, XM_005013197.2

Genome annotation databases

EnsembliENSAPLT00000005568; ENSAPLP00000004944; ENSAPLG00000005396
GeneIDi101804920
KEGGiapla:101804920

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ADON01030700 Genomic DNA No translation available.
KB742651 Genomic DNA Translation: EOB05907.1
RefSeqiXP_005013252.1, XM_005013195.2
XP_005013254.1, XM_005013197.2

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSAPLT00000005568; ENSAPLP00000004944; ENSAPLG00000005396
GeneIDi101804920
KEGGiapla:101804920

Organism-specific databases

CTDi56262

Phylogenomic databases

GeneTreeiENSGT00920000148937
KOiK22038
OMAiVDTQPAY
OrthoDBiEOG091G01ER

Family and domain databases

Gene3Di3.80.10.10, 2 hits
InterProiView protein in InterPro
IPR001611 Leu-rich_rpt
IPR003591 Leu-rich_rpt_typical-subtyp
IPR032675 LRR_dom_sf
IPR038960 LRRC8
IPR021040 LRRC8_Pannexin-like
PANTHERiPTHR43945 PTHR43945, 1 hit
PfamiView protein in Pfam
PF13855 LRR_8, 3 hits
PF12534 Pannexin_like, 1 hit
SMARTiView protein in SMART
SM00369 LRR_TYP, 8 hits
PROSITEiView protein in PROSITE
PS51450 LRR, 12 hits
ProtoNetiSearch...

Entry informationi

Entry nameiR0K7Z6_ANAPL
AccessioniPrimary (citable) accession number: R0K7Z6
Entry historyiIntegrated into UniProtKB/TrEMBL: June 26, 2013
Last sequence update: June 26, 2013
Last modified: June 20, 2018
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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